Penn Veterinary Medicine | University of Pennsylvania

Description of Research Expertise

Research Interests:
a) Oral pathology of small animals, with a focus on oral neoplasms.
b) Neuropathology of small animals.
c) Virology, with a focus on natural and experimental viral diseases.

Description of Clinical Expertise

Diagnostic pathology on our surgical biopsy service with an interest in oral pathology and neuropathology as well as participation in our autopsy (necropsy) service.

Selected Publications

Piviani Martina, Sánchez Melissa D, Patel Reema T: Cytologic features of clear cell adnexal carcinoma in 3 dogs. Veterinary clinical pathology / American Society for Veterinary Clinical Pathology 41(3): 405-11, Sep 2012.

Desoutter A V, Goldschmidt M H, Sánchez M D: Clinical and Histologic Features of 26 Canine Peripheral Giant Cell Granulomas (Formerly Giant Cell Epulis). Veterinary pathology Mar 2012.

Sænchez Melissa D, Orita Vivian M, Nolan Thomas J: Pathology in practice. Focally extensive granulomatous and eosinophilic conjunctivitis with numerous intralesional nematodes, consistent with Onchocerca spp. Journal of the American Veterinary Medical Association 240(4): 385-7, Feb 2012.

Flood-Knapik K E, Durham A C, Gregor T P, Sánchez M D, Durney M E, Sorenmo K U: Clinical, histopathological and immunohistochemical characterization of canine indolent lymphoma. Veterinary and comparative oncology Feb 2012.

Sánchez Melissa D, Goldschmidt Michael H, Mauldin Elizabeth A: Herpesvirus dermatitis in two cats without facial lesions. Veterinary dermatology 23(2): 171-3, e35, Apr 2012.

Koch Michael W, Sánchez Melissa D, Long Sam: Multifocal oligodendroglioma in three dogs. Journal of the American Animal Hospital Association 47(5): e77-85, Sep-Oct 2011.

Kallewaard Nicole L, Zhang Lili, Chen Jin-Wen, Guttenberg Marta, Sanchez Melissa D, Bergelson Jeffrey M: Tissue-specific deletion of the coxsackievirus and adenovirus receptor protects mice from virus-induced pancreatitis and myocarditis. Cell host & microbe 6(1): 91-8, Jul 2009.

Hobson-Peters Jody, Toye Philip, Sánchez Melissa D, Bossart Katharine N, Wang Lin-Fa, Clark David C, Cheah Wai Yuen, Hall Roy A: A glycosylated peptide in the West Nile virus envelope protein is immunogenic during equine infection. The Journal of general virology 89(Pt 12): 3063-72, Dec 2008.

Magee B B, Sanchez Melissa D, Saunders David, Harris David, Berriman M, Magee P T: Extensive chromosome rearrangements distinguish the karyotype of the hypovirulent species Candida dubliniensis from the virulent Candida albicans. Fungal genetics and biology : FG & B 45(3): 338-50, Mar 2008.

Sánchez Melissa D, Pierson Theodore C, Degrace Marciela M, Mattei Lisa M, Hanna Sheri L, Del Piero Fabio, Doms Robert W: The neutralizing antibody response against West Nile virus in naturally infected horses. Virology 359(2): 336-48, Mar 2007.

Davis Carl W, Nguyen Hai-Yen, Hanna Sheri L, Sánchez Melissa D, Doms Robert W, Pierson Theodore C: West Nile virus discriminates between DC-SIGN and DC-SIGNR for cellular attachment and infection. Journal of virology 80(3): 1290-301, Feb 2006.

Pierson Theodore C, Sánchez Melissa D, Puffer Bridget A, Ahmed Asim A, Geiss Brian J, Valentine Laura E, Altamura Louis A, Diamond Michael S, Doms Robert W: A rapid and quantitative assay for measuring antibody-mediated neutralization of West Nile virus infection. Virology 346(1): 53-65, Mar 2006.

Hanna Sheri L, Pierson Theodore C, Sanchez Melissa D, Ahmed Asim A, Murtadha Mariam M, Doms Robert W: N-linked glycosylation of west nile virus envelope proteins influences particle assembly and infectivity. Journal of virology 79(21): 13262-74, Nov 2005.

Sánchez Melissa D, Pierson Theodore C, McAllister Douglas, Hanna Sheri L, Puffer Bridget A, Valentine Laura E, Murtadha Mariam M, Hoxie James A, Doms Robert W: Characterization of neutralizing antibodies to West Nile virus. Virology 336(1): 70-82, May 2005.

Milstone Aaron M, Petrella JenniElizabeth, Sanchez Melissa D, Mahmud Mariam, Whitbeck J Charles, Bergelson Jeffrey M: Interaction with coxsackievirus and adenovirus receptor, but not with decay-accelerating factor (DAF), induces A-particle formation in a DAF-binding coxsackievirus B3 isolate. Journal of virology 79(1): 655-60, Jan 2005.

Puffer Bridget A, Pöhlmann Stefan, Edinger Aimee L, Carlin Dan, Sanchez Melissa D, Reitter Julie, Watry Debbie D, Fox Howard S, Desrosiers Ronald C, Doms Robert W: CD4 independence of simian immunodeficiency virus Envs is associated with macrophage tropism, neutralization sensitivity, and attenuated pathogenicity. Journal of virology 76(6): 2595-605, Mar 2002.

Pöhlmann S, Baribaud F, Lee B, Leslie G J, Sanchez M D, Hiebenthal-Millow K, Münch J, Kirchhoff F, Doms R W: DC-SIGN interactions with human immunodeficiency virus type 1 and 2 and simian immunodeficiency virus. Journal of virology 75(10): 4664-72, May 2001.