Penn Veterinary Medicine | University of Pennsylvania

Selected Publications

Read Jennifer R, Boston Raymond C, Abraham Getu, Bauquier Sebastien H, Soma Lawrence R, Nolen-Walston Rose D: Effect of prolonged administration of clenbuterol on airway reactivity and sweating in horses with inflammatory airway disease. American journal of veterinary research 73(1): 140-5, Jan 2012.

Guan Fuyu, Uboh Cornelius E, Soma Lawrence R, You Youwen, Li Xiaoqing, McDonnell Sue: Ex vivo spontaneous generation of 19-norandrostenedione and nandrolone detected in equine plasma and urine. The Journal of steroid biochemistry and molecular biology 128(1-2): 1-11, Jan 2012.

Liu Ying, Uboh Cornelius E, Soma Lawrence R, Li Xiaoqing, Guan Fuyu, You Youwen, Chen Jin-Wen: Efficient use of retention time for the analysis of 302 drugs in equine plasma by liquid chromatography-MS/MS with scheduled multiple reaction monitoring and instant library searching for doping control. Analytical chemistry 83(17): 6834-41, Sep 2011.

Soma Lawrence R, Uboh Cornelius E, You Yowen, Guan Fuyu, Boston Raymond C: Pharmacokinetics of intra-articular, intravenous, and intramuscular administration of triamcinolone acetonide and its effect on endogenous plasma hydrocortisone and cortisone concentrations in horses. American journal of veterinary research 72(9): 1234-42, Sep 2011.

Liu Ying, Uboh Cornelius E, Soma Lawrence R, Li Xiaoqing, Guan Fuyu, You Youwen, Rudy Jeffrey A, Chen Jin-Wen: Detection and confirmation of 60 anabolic and androgenic steroids in equine plasma by liquid chromatography-tandem mass spectrometry with instant library searching. Drug testing and analysis 3(1): 54-67, Jan 2011.

Mangal Dipti, Uboh Cornelius E, Soma Lawrence R: Analysis of bioactive eicosanoids in equine plasma by stable isotope dilution reversed-phase liquid chromatography/multiple reaction monitoring mass spectrometry. Rapid communications in mass spectrometry : RCM 25(5): 585-98, Mar 2011.

Liu Ying, Uboh Cornelius E, Soma Lawrence R, Li Xiaoqing, Guan Fuyu, You Youwen, Rudy Jeffrey A, Chen Jin-Wen: Analysis of gabapentin in equine plasma with measurement uncertainty estimation by liquid chromatography-tandem mass spectrometry. Journal of analytical toxicology 35(2): 75-84, Mar 2011.

Guan Fuyu, Uboh Cornelius E, Soma Lawrence R, Rudy Jeffrey: Sequence elucidation of an unknown cyclic peptide of high doping potential by ETD and CID tandem mass spectrometry. Journal of the American Society for Mass Spectrometry 22(4): 718-30, Apr 2011.

Guan Fuyu, Uboh Cornelius E, Soma Lawrence R, Maylin George, Jiang Zibin, Chen Jinwen: Confirmatory Analysis of Continuous Erythropoietin Receptor Activator and Erythropoietin Analogues in Equine Plasma by LC-MS for Doping Control. Analytical chemistry Oct 2010.

You Youwen, Uboh Cornelius E, Soma Lawrence R, Guan Fuyu, Li Xiaoqing, Liu Ying, Rudy Jeffrey A, Chen Jinwen, Tsang Deborah: Simultaneous separation and determination of 16 testosterone and nandrolone esters in equine plasma using ultra high performance liquid chromatography-tandem mass spectrometry for doping control. Journal of chromatography. A 1218(26): 3982-93, Jul 2011.

Guan Fuyu, Uboh Cornelius E, Soma Lawrence R, You Youwen, Liu Ying, Li Xiaoqing: High-throughput UHPLC-MS/MS method for the detection, quantification and identification of fifty-five anabolic and androgenic steroids in equine plasma. Journal of mass spectrometry : JMS 45(11): 1270-9, Nov 2010.

Chen Jin-Wen, Uboh Cornelius E, Soma Lawrence R, Li Xiaoqing, Guan Fuyu, You Youwen, Liu Ying: Determining the source of equine bloodstains by dinucleotide repeats. Journal of forensic sciences 55(6): 1610-4, Nov 2010.

Chen Jin-Wen, Uboh Cornelius E, Soma Lawrence R, Li Xiaoqing, Guan Fuyu, You Youwen, Liu Ying: Identification of racehorse and sample contamination by novel 24-plex STR system. Forensic science international. Genetics 4(3): 158-67, Apr 2010.

Soma LR, Guan F, Uboh CE, Luo Y, Driessen B: Pharmacokinetics of hemoglobin-based oxygen carrier-200 (HBOC-200; Oxyglobin®) in the Horse. Anesthesia & Analgesia 100: 1570-1575, 2005.

Luo Y, Uboh CE, Soma LR, Guan F, Rudy JA, Tsang DS: Simultaneous analysis of twenty-one glucocorticoids in equine plasma by liquid chromatography/tandem mass spectrometry. Rapid Communications in Mass Spectrometry 19: 1245-1256, 2005.

Guan F, Uboh CE, Soma LR, Luo Y, Rudy J, Tobin T: Detection, quantification and confirmation of anabolic steroids in equine plasma by liquid chromatography and tandem mass spectrometry. Journal of Chromatography B 829: 56-59, 2005.

Soma LR, Uboh CE, Luo Y, Guan F, Moat PJ, Boston RC: Pharmacokinetics of Intra-articular Administration of Methylprednisolone Acetate: Effect on Endogenous Hydrocortisone and Cortisone in the Horse. American Journal of Veterinary Research 67(4): 654-662 , 2006.

Guan F, CE Uboh, LR Soma, Y Luo, and S Petterman: Collision-induced decomposition of anabolic steroids by electrospray ionization quadrupole time-of-flight (QTOF). Mass Spectrometry 17(4): 477-489, 2006.

Lankveld DPK, Driessen B, Soma LR, Moate PJ, Rudy J, Uboh CE, van Dijk P & Hellebrekers LJ: Pharmacodynamic effects and pharmacokinetic profile of a long-term continuous rate infusion of racemic ketamine in healthy conscious horses. Journal of Veterinary Pharmacology & Therapeutics 29 : 477-488 , 2006.

Orsini JA, Moate PJ, Kuersten K, Soma LR, Boston RC: Pharmacokinetics of fentanyl delivered transdermally in healthy adult horses-variability among horses and clinical implications. Journal of Veterinary Pharmacology & Therapeutics 29: 539-546, 2006.

Soma LR, Uboh CE, Guan F, McDonnell S, Pack J: Pharmacokinetics of Boldenone and Stanozolol and the Results of Screening for Anabolic and Androgenic Steroids and in Race Horses and Non-Race Horses. Journal of Veterinary Pharmacology & Therapeutics 30: 101-108, 2006.

Guan F, Uboh CE, Soma LR, Birks E, Chen J, You Y, Xu F, Mbuy G: Extraction and Confirmation of Recombinant Human Epo and Darbepoetin-Alpha in Equine Plasma by LC-MS. Anal Chem 79: 4627-4635 , 2007.

You Y, Uboh CE, Soma LR, Guan F, Rudy J: Determination of Alcohol Administration Biomarkers: Ethyl Glucuronide and Ethyl Sulfate in Equine Urine by Liquid Chromatography-Tandem Mass Spectrometry. Rapid Communications Mass Spectrometry 21: 3785-3794, 2007.