Penn Veterinary Medicine | University of Pennsylvania

Description of Research Expertise

My primary expertise and research interest is orthopedic pathology with focus on equine laminitis. A current project involves collaboration with UPENN's Laminitis Institute at the School of Veterinary Medicine, New Bolton Center. The goal of the project is to systematically characterize and grade the histopathological changes that occur within the pedal bone and sensitive lamina of the hoof during and after naturally occurring episodes of laminitis. This data is to be correlated with pathological molecular (genomic & proteomic) data analyzed by Dr. Hannah Gallantino-Homer's Laboratory.

A secondary focus involves collaboration with Dr. Thomas Schaer at the New Bolton Center's Comparative Orthopedic Research Laboratory (CORL), which utilizes various animal models to evaluate experimental orthopedic surgical implant devices and biomaterials.

A tertiary research interest pertains to gastrointestinal pathology in horses (post ischemic injury, inflammation and post-surgical enteric wound healing). This is a collaboration with Dr. Louise Southwood, Dept. of Clinical Studies- New Bolton Center.

Orthopedic research affiliations
Drs. Christopher Pollitt, James Orsini, Hanah Galatino-Homer, Andrew Van Eps, Patrick Reilly- Laminitis Institute, New Bolton Center
Dr. Tomas Schaer- CORL (Comparative Orthopedic Research Laboratory), NBC

Gastrointestinal research affiliations
Dr. Louise Southwood- Dept. of Clinical Studies, NBC

Selected Publications

Stewart Suzanne, Barr Stephanie, Engiles Julie, Hickok Noreen J, Shapiro Irving M, Richardson Dean W, Parvizi Javad, Schaer Thomas P: Vancomycin-modified implant surface inhibits biofilm formation and supports bone-healing in an infected osteotomy model in sheep: a proof-of-concept study. The Journal of bone and joint surgery. American volume 94(15): 1406-15, Aug 2012.

Morello Samantha, Southwood Louise L, Engiles Julie, Slack Joann, Crack Aaron, Springate Christopher M K: Effect of intraperitoneal PERIDAN™ concentrate adhesion reduction device on clinical findings, infection, and tissue healing in an adult horse jejunojejunostomy model. Veterinary surgery : VS 41(5): 568-81, Jul 2012.

Stock ML, Smith BI, Engiles JB: Disseminated hemangiosarcoma in a cow Canadian Veterinary Journal 52: 409-413, April 2011.

R.A. Carter, J.B. Engiles, S.O. Megee, M. Senoo, H.L. Galantino-Homer. : Decreased expression of p63, a regulator of epidermal stem cells, in the chronic laminitic equine hoof. Equine Veterinary Journal. Page: Epub., Mar 2011.

Mason JB, Cargill SL, Griffey SM, Reader JR, Anderson GB, Carey JR: Transplantation of young ovaries restored cardioprotective influence in postreproductive-aged mice Aging Cell Page: Epub, Mar 2011.

GA Tyner, RD Nolen-Walston, T Hall, JP Palmero, L Coutëil, L Javsicas, A Stack, H Schott, A Johnson, L Hardefeldt, A Gruntman, C Sommardahl, N Menzies-Gow, P dePedro, T Norman, LC Fennell, JE Axon, S Lindborg, H Aceto, R Boston, J Engiles.: A multicenter retrospective study of 151 renal biopsies in horses Journal of Veterinary Internal Medicine Page: Epub., Jan 2011.

James, Frances M. Engiles, Julie B. Beech, Jill.: Meningitis, cranial neuritis, and radiculoneuritis associated with Borrelia burgdorferi infection in a horse. Journal of the American Veterinary Medical Association 237(10): 1180-5, Nov 15 2010.

Engiles, Julie B.: Pathology of the distal phalanx in equine laminitis: more than just skin deep. [Review] [43 refs] Veterinary Clinics of North America - Equine Practice 26(1): 155-65, Apr 2010.

Ahern, B. J. Engiles, J. Smith, J. J. Parente, E. J.: Paranasal sinus fibromatosis in a horse. Equine Veterinary Education. 22(1): 23-28, 2010.

Nolen-Walston, R D. Parente, E J. Madigan, J E. David, F. Knafo, S E. Engiles, J B.: Branchial remnant cysts of mature and juvenile horses. Equine Veterinary Journal 41(9): 918-23, Dec 2009.

H.L. Reesink*, E.J. Parente, P.L. Sertich, J.B. Engiles*. : Malignant fibrous histiocytoma of the mammary gland in a mare. Equine Veterinary Education. 2009..

M. A. Smith*, D. G. Levine, L. M. Getman, E. J. Parente, J. B. Engiles.*: Vulvar squamous cell carcinoma in situ within viral papillomas in an aged Quarter Horse mare. Equine Veterinary Education. 21:1: 11-16, 2009.