Penn Veterinary Medicine | University of Pennsylvania

Description of Research Expertise

bone biology
mesenchymal stem cell
orthopaedic tissue engineering
Bone regeneration and repair
Osteoporosis
Extracellular Matrix
Stem Cells
Bone regeneration/repair
Mesenchymal Stem Cell
Osteoporosis
Orthopaedic tissue engineering

Selected Publications

Singh Lakshman, Brennan Tracy A, Kim Jung-Hoon, Egan Kevin P, McMillan Emily A, Chen Qijun, Hankenson Kurt D, Zhang Yi, Emerson Stephen G, Johnson F Brad, Pignolo Robert J: Long-term functional engraftment of mesenchymal progenitor cells in a mouse model of accelerated aging. Stem cells (Dayton, Ohio) 31(3): 607-11, Mar 2013.

Zhu Fengchang, Sweetwyne Mariya T, Hankenson Kurt D: Pkcd Is Required for Jagged-1 Induction of hMSC Osteogenic Differentiation. Stem cells (Dayton, Ohio) Feb 2013.

Zhu Fengchang, Friedman Michael S, Luo Weijun, Woolf Peter, Hankenson Kurt D: The transcription factor osterix (SP7) regulates BMP6-induced human osteoblast differentiation. Journal of cellular physiology 227(6): 2677-85, Jun 2012.

Miedel Emily, Dishowitz Michael I, Myers Marc H, Dopkin Derek, Yu Yan-Yiu, Miclau Ted S, Marcucio Ralph, Ahn Jaimo, Hankenson Kurt D: Disruption of thrombospondin-2 accelerates ischemic fracture healing. Journal of orthopaedic research : official publication of the Orthopaedic Research Society Dec 2012.

Volk Susan W, Wang Yanjian, Hankenson Kurt D: Effects of donor characteristics and ex vivo expansion on canine mesenchymal stem cell properties: implications for MSC-based therapies. Cell transplantation 21(10): 2189-200, 2012.

Dishowitz Michael I, Terkhorn Shawn P, Bostic Sandra A, Hankenson Kurt D: Notch signaling components are upregulated during both endochondral and intramembranous bone regeneration. Journal of orthopaedic research : official publication of the Orthopaedic Research Society 30(2): 296-303, Feb 2012.

Hankenson Kurt D, Dishowitz Michael, Gray Chancellor, Schenker Mara: Angiogenesis in bone regeneration. Injury 42(6): 556-61, Jun 2011.

Laurita Jason, Koyama Eiki, Chin Bianca, Taylor Jesse A, Lakin Gregory E, Hankenson Kurt D, Bartlett Scott P, Nah Hyun-Duck: The Muenke syndrome mutation (FgfR3P244R) causes cranial base shortening associated with growth plate dysfunction and premature perichondrial ossification in murine basicranial synchondroses. Developmental dynamics : an official publication of the American Association of Anatomists 240(11): 2584-96, Nov 2011.

Scheller Erica L, Leinninger Gina M, Hankenson Kurt D, Myers Martin G, Krebsbach Paul H: Ectopic expression of Col2.3 and Col3.6 promoters in the brain and association with leptin signaling. Cells, tissues, organs 194(2-4): 268-73, 2011.

Lin Grace L, Hankenson Kurt D: Integration of BMP, Wnt, and notch signaling pathways in osteoblast differentiation. Journal of cellular biochemistry 112(12): 3491-501, Dec 2011.

Scheller Erica L, Hankenson Kurt D, Reuben Jayne S, Krebsbach Paul H: Zoledronic acid inhibits macrophage SOCS3 expression and enhances cytokine production. Journal of cellular biochemistry 112(11): 3364-72, Nov 2011.

Luo Weijun, Friedman Michael S, Hankenson Kurt D, Woolf Peter J: Time series gene expression profiling and temporal regulatory pathway analysis of BMP6 induced osteoblast differentiation and mineralization. BMC systems biology 5: 82, 2011.