Scientists Report First Transgenic Animal Developed Via Retroviral DNA Insertion Into Male Germ-Line Stem Cells
Saturday, September 22, 2001
PHILADELPHIA - Scientists at the University of Pennsylvania School of Veterinary Medicine have successfully used a retrovirus to modify genes in spermatogonial stem cells in a mouse - the first instance, in any species, of a transgenic animal created by inserting a gene into male germ-line stem cells.
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Penn's School of Veterinary Medicine is one of the world's premier veterinary schools. Founded in 1884, the School was built on the concept of Many Species, One Medicine™. The birthplace of veterinary specialties, the School serves a distinctly diverse array of animal patients, from pets to horses to farm animals at our two campuses. In Philadelphia, on Penn's campus, are the Matthew J. Ryan Veterinary Hospital for companion animals, as well as classrooms, laboratories and the School's administrative offices. The large-animal facility, New Bolton Center, in Kennett Square, Pa., encompasses hospital facilities for the care of horses and food animals as well as diagnostic laboratories serving the agriculture industry. The School has successfully integrated scholarship and scientific discovery with all aspects of veterinary medical education.
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