Penn Veterinary Medicine | University of Pennsylvania

Funded Projects - 2012

Student:  Michelle Acierno
Title of Project:  Differentiation of DEA 1 expression on canine erythrocytes: Analysis of genetic and temporal effects on antigen levels by tube, strip, and flow cytometry techniques
Mentor:  Urs Giger
Department:  Clinical Studies, Philadelphia, Veterinary Medicine

Student:  Robyn Allen
Title of Project:  Mitochondrial DNA as a Determinant of Outcomes after Heart Attack and a Possible Target for Improving Reperfusion Therapy
Mentor:  Brett Kaufman
Department:  Animal Biology, Veterinary medicine

Student:  Elizabeth Golden (nee Boush)
Title of Project:  The role of wound healing macrophages in the resolution of leishmaniasis
Mentor:  Phil Scott
Department:  Pathobiology, Veterinary Medicine

Student:  Stephen Cole
Title of Project:  Allelic substitutions of host-specific adhesins of Salmonella
Mentor:  Dieter Schifferli
Department:  Pathobiology, Veterinary Medicine

Student:  Chelsea del Alcazar
Title of Project:  Characterization of spinal lesions in the canine model of Mucopolysaccharidosis VII
Mentor:  Mark Haskins
Department:  Pathobiology, Veterinary Medicine

Student:  Kreig Embriano
Title of Project:  Alteration of the Hematopoietic Niche in Perlecan Hypomorphic Mice
Mentor:  Olena Jacenko
Department:  Animal Biology, Veterinary Medicine

Student:  Kristin Gardiner
Title of Project:  Determination of the Mechanisms of Early Retinal Degeneration in the Canine Models  erd, XLPRA2, and rcd1
Mentor:  Gustavo Aguirre
Department:  Clinical Studies, Philadelphia, Veterinary Medicine

Student:  Sam Gilbert
Title of Project:  PennHIP Hands-Free Device
Mentor:  Gail Smith
Department:  Clinical Studies, Philadelphia, Veterinary Medicine

Student:  Lauren Harris
Title of Project:  The Role of Type III Collagen in Post-Injury Renal Fibrosis
Mentor:  Susan Volk
Department:  Clinical Studies, Philadelphia, Veterinary Medicine

Student:  Rebecca King
Title of Project:  Host-Oriented Therapeutics to Inhibit Budding and Spread of Arenaviruses
Mentor:  Ronald Harty
Department:  Pathobiology, Veterinary Medicine

Student:  Britt Levy
Title of Project:  The Molecular Characterization of Congenital Follicular Parakeratosis in the Labrador Retriever Dog
Mentor:  Margret Casal
Department:  Clinical Studies, Philadelphia, Veterinary Medicine

Student:  Austin Luskin
Title of Project:  The Evolution of Original Antigenic Sin in Lyme Disease
Mentor:  Dustin Brisson
Department:  Biology

Student:  Bridget Lyons
Title of Project:  Development of a point-of-care isothermal nucleic acid amplification assay for the rapid diagnosis of bacteremia in septic dogs and cats
Mentor:  Shelly Rankin
Department:  Pathobiology, Veterinary Medicine

Student:  Katelyn MacGillivray
Title of Project:  Regulation of NFAT and NF-kB transcriptional Activity by Ca2+ Signals in Lymphocytes
Mentor:  Bruce Freedman
Department:  Pathobiology, Veterinary Medicine

Student:  Andrea Moffitt
Title of Project:  The effects of liver-specific nicotinamide phosphoribosyltransferase (Nampt) overexpression in transgenic mice with respect to NAD+ concentration and protection from high-fat diet
Mentor:  Joseph Baur
Department:  Physiology

Student:  Marc Myers
Title of Project:  Evaluating Hypoxia in Ischemic Tibial Fractures
Mentor:  Kurt Hankenson
Department:  Animal Biology, Veterinary Medicine

Student:  Shannon Palermo
Title of Project:  Prehydration Requirements of Working Dogs
Mentor:  Cynthia Otto
Department:  Clinical Studies, Philadelphia, Veterinary Medicine

Student:  Diana Richerson
Title of Project:  The Role of Smac Mimetic Compounds in the Regulation of the Classical NFkB Activation
Mentor:  Michael May
Department:  Animal Biology, Veterinary Medicine

Student:  Peri Rosenstein
Title of Project:  Multispecies transmission dynamics of the raccoon rabies ecotype in Pennsylvania
Mentor:  Gary Smith
Department:  Clinical Studies, New Bolton Center, Veterinary Medicine

Student:  John Sopronyi
Title of Project:  Characterization of the Role of Placental Leptin Signaling on Long-term Neurobehavioral Function
Mentor:  Tracy Bale
Department:  Animal Biology, Veterinary Medicine                                                                                                                                                                     

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Funded Projects - 2011                                                                                                                                           Back to Top               

Student:  Nadia Azam
Title of Project:   Evaluation of Neuropeptide Expression in Feline Hypothalami and Correlation with Body Weight and Fed Status
Mentor:  Kendra Bence and Erika Krick
Department:  Clinical Studies, Philadelphia, Veterinary Medicine

Student:  Benoit Clerc-Renaud
Title of Project:   Antiviral Activity of Innate Immune Protein Viperin on Filovirus Assembly/Budding
Mentor:  Ronald Harty
Department:  Pathobiology, Veterinary Medicine

Student:  Suzanne DiNello
Title of Project:   The Effect of AICAR (5-amino-4-imidazolecarboxamide riboside) on AMP-activated Protein Kinase in Equine Red Blood Cells and Skeletal Muscle Cells
Mentor:  Mary Robinson
Department:  Clinical Studies, New Bolton Center, Veterinary Medicine

Student:  Hope Douglas
Title of Project:   The use of PARP1 inhibitors for the prevention of intestinal ischemia-reperfusion injury in horses with colic
Mentor:  Louise Southwood
Department:  Clinical Studies, New Bolton Center, Veterinary Medicine

Student:  Lauren Duffee
Title of Project:   The Role of Nitric Oxide in Laminitis
Mentor:  Hannah Galantino-Homer
Department:  Clinical Studies, New Bolton Center, Veterinary Medicine

Student:  Kristin Lee Gardiner
Title of Project:   Photoreceptor cell proliferation in canine early retinal degeneration models
Mentor:  Gustavo Aguirre
Department:  Clinical Studies, Philadelphia, Veterinary Medicine

Student:  Hadley Gleason
Title of Project:   Demonstrating a Role for Collagen 3 in Murine Fracture Repair
Mentor:  Susan Volk
Department:  Clinical Studies, Philadelphia, Veterinary Medicine

Student:  Su Li
Title of Project:   Neuropathologic studies of brain in a feline model of Niemann-Pick type C disease
Mentor:  Charles Vite
Department:  Clinical Studies, Philadelphia, Veterinary Medicine

Student:  Richard Lyons
Title of Project:   Isolation and Characterization of an EBV-Related Herpesvirus From Dogs with B Cell Lymphoma
Mentor:  Nicola Mason
Department:  Clinical Studies, Philadelphia, Veterinary Medicine

Student:  Anna Nomura
Title of Project:   Elucidation of the Molecular Basis of Lethal Acrodermatitis in Bull Terriers
Mentor:  Margaret Casal
Department:  Clinical Studies, Philadelphia, Veterinary Medicine

Student:  Annie Oh
Title of Project:   Molecular Mechanisms of CNTF-Induced Photoreceptor Deconstruction
Mentor:  Andreas Komaromy
Department:  Clinical Studies, Philadelphia, Veterinary Medicine

Student:  Thomas Parmentier
Title of Project:   Research project in the field of gene therapy for the neurogenetic disease, using a animal model of human disease.
Mentor:  John Wolfe
Department:  Pathobiology, Veterinary Medicine

Student:  Carolyn Powell
Title of Project:   The role of corticotropin releasing factor receptor-1 (CRFR1) in the dorsal raphe nucleus on stress responsivity
Mentor:  Tracy Bale
Department:  Animal Biology, Veterinary Medicine

Student:  Diana Richerson
Title of Project:   The Role of Smac Mimetic Compounds in the Regulation of the Classical and Non-canonical NFkB Pathways
Mentor:  Michael May
Department:  Animal Biology, Veterinary Medicine

Student:  Tiffany L. Sikalas
Title of Project:   Evaluation of a Cardiovascular Function in Canine Mucopolysaccharidosis Type I and VII Heterozygotes
Mentor:  Margaret Sleeper
Department:  Clinical Studies, Philadelphia, Veterinary Medicine

Student:  Kristine Stellato
Title of Project:   Signs or no signs – to what degree are wild Mid-Atlantic birds carrying anticoagulant rodenticides?
Mentor:  Lisa Murphy
Department:  Clinical Studies, New Bolton Center, Veterinary Medicine

Student:  Joel Takacs
Title of Project:   Regulation of osteoblast differentation by Jagged-1 Notch signaling
Mentor:  Kurt Hankenson
Department:  Animal Biology, Veterinary Medicine

Student:  Marjorie van Saun
Title of Project:   Assessments of Fluid Therapy and Body Temperature Monitoring for Establishing Humane Endpoints in Rodent Models of Infectious Disease
Mentor:  F. Claire Hankenson
Department:  Pathobiology, Veterinary Medicine

Student:  Bryan Vorbach
Title of Project:   Efficacy of Bacterial LPS, Peptidoglycan and ß-glucan as Immunostimulants for fish mucosal surfaces
Mentor:  Oriol Sunyer
Department:  Pathobiology, Veterinary Medicine

Student:  Claire Wiley
Title of Project:   Genome-wide Association Study of PLE/PLN (Protein-losing Enteropathy/Nephropathy) in Soft-coated Wheaten Terriers
Mentor:  Paula Henthorn
Department:  Clinical Studies, Philadelphia, Veterinary Medicine

Student:  Ashley Nikki Wright
Title of Project:   Isolation and characterization of a canine derived Single Chain Variable Fragment that binds canine CD20.
Mentor:  Nicola Mason
Department:  Clinical Studies, Philadelphia, Veterinary Medicine

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Funded Projects - 2010                                                                                                              

Student:  Morgan Agnew
Title of Project:   The Use of Exogenous Oxytocin to Prolong Corpora Luteal Function and Suppress Estrous Behavior in Mars During the Natural Breeding Season
Mentor:  Dirk Vanderwall
Department:  Clinical Studies, Philadelphia, Veterinary Medicine

Student:  Sandra Bostic
Title of Project:   Role of Jagged-1 in Fracture Healing
Mentor:  Kurt Hankenson
Department:  Animal Biology, Veterinary Medicine

Student:  Nancy Callori
Title of Project:   Adherence of Methicillin Resistant Staphylococcus aureus to Equine Corneocytes
Mentor:  Shelly Rankin and Dan Morris
Department:  Pathobiology, Veterinary Medicine

Student:  Natalie Fickel
Title of Project:   Establishing Perlecan Hypomorphic Mice as a Unique Model for Avascular Necrosis of the Femoral Head
Mentor:  Olena Jacenko                    
Department:  Animal Biology, Veterinary Medicine
 
Student:  Lauren Hakkinen
Title of Project:   Rescue of Sex-Specific Prenatal Stress Programming by Anti-Inflammatory Treatment
Mentor:  Tracy Bale
Department:  Animal Biology, Veterinary Medicine

Student:  Megan A. Hays
Title of Project:   The Role of Wnt11 in Mesenchymal Stem Cell Differentiation
Mentor:  Kurt Hankenson
Department:  Animal Biology, Veterinary Medicine

Student:  Kaitlyn Hellner-Burris
Title of Project:   Maternal High Fat Diet on Offspring Macronutrient Choice Preferences
Mentor:  Tracy Bale
Department:  Animal Biology, Veterinary Medicine

Student:  Shannon Kerrigan
Title of Project:   The Effect of Substance P on Cellular Responses Induced by HIV Viral Proteins in U373MG Astrocytoma Cells
Mentor:  Steven D. Douglas
Department:  Children’s Hospital of Philadelphia, School of Medicine

Student:  Russ Lapierre
Title of Project:   Assessment of Heart Rate Variability for Prognostic Value Relating  to Underlying Physical Stress and Decreased Performance in Thoroughbred Race Horses
Mentor:  Meg Sleeper
Department:  Clinical Studies, Philadelphia, Veterinary Medicine

Student:  Jessica W. Lee
Title of Project:   Biochemical and Molecular Characterization of Cystinuria in Irish Terriers and Miniature Pinschers
Mentor:  Urs Giger
Department:  Clinical Studies, Philadelphia, Veterinary Medicine

Student:  John Litterine-Kaufman
Title of Project:   Understanding Mitochondrial DNA Damage During Myocardial Infarction of the Heart
Mentor:  Brett Kaufman
Department:  Animal Biology, Veterinary Medicine

Student:  Sarah Mainardi
Title of Project:   Selective Culture of Equine Corneal Epidermal Stem Cells
Mentor:  Hannah Galantino-Homer
Department:  Clinical Studies, New Bolton Center, Veterinary Medicine

Student:  Diane McDonald
Title of Project:  Osteolysis and Lamellar Wedge Formation in Chronic Laminitis
Mentor:  Hannah Galantino-Homer
Department:  Clinical Studies, New Bolton Center, Veterinary Medicine

Student:  Erin McGowan
Title of Project:   Evaluation of Ex Vivo Expansion Techniques to Generate Functional, Immunosuppressive Regulatory T Cells for Use in Clinical Transportation Medicine
Mentor:  Nicola Mason and Lily Aronson
Department:  Clinical Studies, Philadelphia, Veterinary Medicine

Student:  Travis Seymour
Title of Project:   Defining a Role for Collagen 3 in the Tumor Microenvironment
Mentor:  Susan Volk
Department:  Clinical Studies, Philadelphia, Veterinary Medicine

Student:  Sarah Ward
Title of Project:   Effect of 2-Hydroxypropyl-beta-cyclodextrin on Neuropathology in a Feline Model of Neimann-Pick Type C Disease
Mentor:  Charles Vite
Department:  Clinical Studies, Philadelphia, Veterinary Medicine

Student:  Jacqueline Wilhemy
Title of Project:  Development of BiMC and bead-based AlphaScreen assays for the investigation of HSV fusion and glycoprotein-receptor interactions
Mentor:  Roselyn J. Eisenberg
Department:  Department of Pathobiology, Veterinary Medicine

Student:  Schuyler Winstead
Title of Project:   Development of the Canine Short Wavelength-Sensitive Cone Electroretinogram
Mentor:  Andras Komaromy
Department:  Clinical Studies, Philadelphia, Veterinary Medicine

Student:  Adam Yoskowitz
Title of Project:   The Effect of Up-regulating Tissue Inhibitor of Metalloproteinase-3 in Healthy and Diseased Equine Articular Cartilage
Mentor:  Dean Richardson
Department:  Clincial Studies, New Bolton Center, Veterinary Medicine

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Funded Projects - 2008

Student:  Rachel Baek
Title of Project:  Functional Immunology of Hematopoietic Embryonic Stem Cells
Mentor:  John McLaughlin
Department:  Animal Biology, Veterinary Medicine

Student: Caroline Cantner
Title of Project:  Molecular Characterization of Ichthyosis in the American Bulldog
Mentor:  Margaret Casal
Department:  Clinical Studies, Philadelphia, Veterinary Medicine

Student: Denise Chang
Title of Project: Evaluation of Novel Alloantibody and Autoantibody Diagnostics to Predict Blood Incompatibilities Prior to and Post Transfusion in Dogs
Mentor: Urs Giger
Department: Clinical Studies, Philadelphia, Veterinary Medicine

Student: Ann Elizabeth Cooper
Title of Project: Mapping of Cone Photoreceptors in the Canine Retina
Mentor: Andras Komaromy
Department: Clinical Studies, Philadelphia, Veterinary Medicine

Student: Heather Fowler
Title of Project: The Effect of Global Warming on the Distribution of Plasmodium relictum in the Hawiian Islands
Mentor: Gary Smith
Department: Clinical Studies, New Botlon Center, Veterinary Medicine

Student: Jessica Fragola
Title of Project: Characteristics of Membrane Fusion of Crimean-Congo Hemorrhagic Fever Virus via Gn and Gc Glycoproteins
Mentor: Robert Doms
Department: Microbiology, School of Medicine

Student: Jennifer Frohlich
Title of Project: Demonstration of an Oct4-Granulin Signaling Axis Regulating Trophoblast Stem Cells
Mentor: George Gerton
Department: OB/GYN, School of Medicine

Student: Maureen Carolyn Gates
Title of Project: The Influence of Prophylactic Medications on Endoparasite Prevalence in Companion Animals: A Time Series Analysis of Cases from a Veterinary Teaching Hospital Between 1984 and 2007
Mentor: Tom Nolan
Department: Pathobiology, Veterinary Medicine

Student: Moira Kelleher
Title of Project: Characterization of NF-?B Activity and the Effects of Its Inhibition by NEMO Binding Domain Peptide in Canine Cancer Cells
Mentor: Nicola Mason
Department: Clinical Studies, Philadelphia, Veterinary Medicine

Student: Alexander Koenigstein
Title of Project: Mechanism of Mitochondrial Respiratory Stress Induced Osteoclast Differentiation
Mentor: Narayan Avadhani
Department: Animal Biology, Veterinary Medicine

Student: Melissa Lewis
Title of Project: Pathotropic Migration of Endogenous Neural Progenitor Cells
Mentor: Charles Vite
Department: Clinical Studies, Philadelphia, Veterinary Medicine

Student: Amanda McCullough
Title of Project: Analysis of the Effects of Lead and/or Mercury Toxicity in Avian Species
Mentor: Lisa Murphy
Department: Clinical Studies, New Bolton Center, Veterinary Medicine

Student: Alexandra O’Keefe
Title of Project: Characterization of Antimicrobial Resistance Genes from Canine and Feline E. coli Isolates Associated with Urinary Tract Infections
Mentor: Dieter Schifferli
Department: Pathobiology, Veterinary Medicine

Student: Bradley Rosato
Title of Project: Canine Myocardial Oxidative Stress Under Normal, Anesthetized and Cardiomyopathic Conditions
Mentor: Meg Sleeper and Narayan Avadhania
Department: Clinical Studies, Philadelphia, Veterinary Medicine

Student: Carrie Lynn Santare
Title of Project: Volumetric Carbon Dioxide to Determine the Efficacy of Chest Compressions During Cardiopulmonary Resuscitation
Mentor: Manuel Boller
Department: Clinical Studies, Philadelphia, Veterinary Medicine

Student: Carolyn Santore
Title of Project: Determining the Effects of Selective Inhibition of NF-?B Signaling on Atherosclerosis In Vivo
Mentor: Michael May
Department: Animal Biology, Veterinary Medicine

Student: Erin Scott
Title of Project: Characterization of Photoreceptor Loss and Inner Retinal Remodeling in a Canine Model of Cone-Rod Dystrophy
Mentor: William Beltran
Department: Clinical Studies, Philadelphia, Veterinary Medicine

Student: Abigail Shearin
Title of Project: Molecular Basis of Canine Cystinuria
Mentor: Paula Henthorn
Department: Clinical Studies, Philadelphia, Veterinary Medicine

Student: Kelly Slattery
Title of Project: Evaluation and Validation of a Method for Microcirculatory Image in a Porcine Cardiac Arrest Model
Mentor: Manuel Boller
Department: Clinical Studies, Philadelphia, Veterinary Medicine

Student: David Vafek
Title of Project: Cause of Death in Myocytes Due to Exposure to Hypoxic Conditions
Mentor: Cindy Otto
Department: Clinical Studies, Philadelphia, Veterinary Medicine

Student: Cory Waxman
Title of Project: In Vitro Maturation of Canine, Feline, Ovine and Human Ovarian Follicles
Mentor: Christos Coutifaris
Department: OB/GYN, School of Medicine

Student: Ashley Yanchik
Title of Project: Meiotic Rescue of ß-Thalassemia
Mentor: John McLaughlin
Department: Animal Biology, Veterinary Medicine

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Funded Projects - 2007

Student: Aimee Colbath
Title of Project: Geographic Risk Factors for Escherichia coli Infection in Cattle in Pennsylvania and New York State
Mentor: Gary Smith
Department: Clinical Studies, New Bolton Center, Veterinary Medicine

Student: Heather Fowler
Title of Project: Characterization of Novel Type 1 and II Transforming Growth Factor-Beta Receptors in Schistosoma mansoni
Mentor: Ed Pearce
Department: Pathobiology, Veterinary Medicine

Student: Maureen Gates
Title of Project: Analyzing the Spread of West Nile Virus Through Mosquito Vectors: A Meta-Analysis
Mentor: Raymond Boston
Department: Clinical Studies, New Bolton Center, Veterinary Medicine

Student: Randi Gold
Title of Project: Pathophysiology of Canine Hip Dysplasia: Does Capsular Fibrosis Serve as Biological Compensation for Hip Laxity and Osteoarthritis
Mentor: Gail Smith
Department: Clinical Studies, Philadelphia, Veterinary Medicine

Student: Michael Jennings
Title of Project: Optimization and Clinical Implementation of Stem Cell-Seeded Nanofiber-Based Tissue Engineered Constructs for Meniscus Repair
Mentor: Robert Mauck
Department: Orthopaedic Surgery, Medicine

Student: Melissa Lewis
Title of Project: Characterization of Cerebrocortical Dysfunction in Feline Niemann-Pick Type C (NPC) Disease
Mentor: Charles Vite
Department: Clinical Studies, Philadelphia, Veterinary Medicine

Student: Peter Midgley
Title of Project: A Mathematical Model for the Transmission Dynamics and Control of Canine Distemper Virus (CDV) Infection in Wild Ethiopian Wolves (Canis simensis)
Mentor: Gary Smith
Department: Clinical Studies, New Bolton Center, Veterinary Medicine

Student: Jamie Minnella
Title of Project: Development and Assessment of a Real-Time PCR Assay for Rapid Detection of Salmonella in Clinical Diagnostic Laboratory Settings
Mentor: Shelley Rankin
Department: Clinical Studies, Philadelphia, Veterinary Medicine

Student: Michelle Nelson
Title of Project: Yersinia pestis Virulence Protein Purification and Experimental Mutant Production
Mentor: Dieter Schifferli
Department: Pathobiology, Veterinary Medicine

Student: Brianne O'Loughlin
Title of Project: Cross Species Comparison of Congenital Heart Defects Involving the Genes Edg2 and MAPK1
Mentor: Sulagna Saitta
Department: Pediatrics, Medicine

Student: Laura Pell
Title of Project: Generation of Canine Single Chain Fragment Variable Antibody Libraries for the Identification and Targeting of Tumor-Associated Antigens in the Dog
Mentor: Nicola Mason
Department: Clinical Studies, Philadelphia, Veterinary Medicine

Student: Miriam Sadek
Title of Project: Mitochondrial Respiratory Stress Induced Tumor Invasion Through Activation of a Novel NF?B Pathway
Mentor: Narayan Avadhani
Department: Animal Biology, Veterinary Medicine

Student: Abigail Shearin
Title of Project: Cystinuria in Dogs
Mentor: Paula Henthorn
Department: Clinical Studies, Philadelphia, Veterinary Medicine

Student: Marissa Sue
Title of Project: Positive Serodiagnosis for Toxoplasma gondii and Leptospira spp. And its Correlation to Serum Biochemical Parameters in Medium and Large Carnivores of Emas National Park, Brazil
Mentor: Karen Rosenthal
Department: Clinical Studies, Philadelphia, Veterinary Medicine

Student: Nancy Hyun Joo Sung
Title of Project: Identification of Correlations Between Canine Behavioral Traits and Specific Health Problems
Mentor: James Serpell
Department: Clinical Studies, Philadelphia, Veterinary Medicine

Student: Samuel Tucker
Title of Project: Innervation of the Canine Intervertebral Disc: An Immunohistochemical Study
Mentor: Thomas Schaer
Department: Clinical Studies, New Bolton Center, Veterinary Medicine

Student: Melissa Vetter
Title of Project: L1 Retrotransportation in a Transgenic Rat Model
Mentor: Haig Kazazian
Department: Genetics, Medicine

Student: Andrea Weissman
Title of Project: A Time Interval Study of the Effect of Intermittent Hypoxia on Nitrate and Nitrite Concentrations in Drosophila melanogaster
Mentor: Cindy Otto
Department: Clinical Studies, Philadelphia, Veterinary Medicine

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Funded Projects - 2006

Student: Lisa Berman
Title of Project: Characterization of the Role of Intestinal Epithelial Cells in the Regulation of CD4+T Helper Cell Responses Following Gut Nematode Infection.
Mentor: David Artis
Department: Pathobiology, Veterinary Medicine

Student: Megan Brace
Title of Project: Multi-Drug Resistant Slmonella Newport in Equine Colic Patients: Can Outcomes and Cluster Analysis Aid in the Development of Better Infection Control and Therapeutic Strategies.
Mentor: Helen Aceto
Department: Clinical Studies, New Bolton Center, Veterinary Medicine

Student: Cara Catanese
Title of Project: Studies on Binding and Invasive Properties of Yersinia pestis Autotransporters.
Mentor: Dieter Schifferli
Department: Pathobiology, Veterinary Medicine

Student: Jennifer Dietz
Title of Project: Longevity of Motility of Spermand Bacteria Present in Equine Semen Stored in Semen Extender Containing Pipercillin.
Mentor: Patricia Sertich, Charles Benson
Department: Clinical Studies, New Bolton Center, Veterinary Medicine and Pathobiology, Veterinary Medicine

Student: Carrie Ellis
Title of Project: Expression and Identification of Yersinia pestis Surface Proteins for Future Vaccine Development Against Plague
Mentor: Dieter Schifferli
Department: Pathobiology, Veterinary Medicine

Student: Jennie Kim
Title of Project: The Effects of L-NAME and Hypoxia on Drosophila Melanogaster.
Mentor: Cindy Otto
Department: Clinical Studies, Philadelphia, Veterinary Medicine

Student: Melissa King
Title of Project: An Analysis of the Oral Rabies Vaccination (ORV) Program in New York State.
Mentor: Gary Smith
Department: Clinical Studies, New Bolton Center, Veterinary Medicine

Student: Diana Knight
Title of Project: Assessing the Effects of Cued Fear Conditioning and the Role of the Amygdala in REM Sleep Patterns of Male S-D Rats.
Mentor: Adrian Morrison
Department: Animal Biology, Veterinary Medicine

Student: Catherine Kusiak
Title of Project: Lysosomal Storage Diseases: An Evaluation of Cardiovascular Function.
Mentor: Meg Sleeper, Mark Haskins
Department: Pathobiology, Veterinary Medicine

Student: Simon Long
Title of Project: The Functional Role of the Membrane Glycoprotein and Small Envelope Protein in the Mouse Hepatitis Virus.
Mentor: Susan Weiss
Department: Microbiology, Medicine

Student: Katherine McKeown
Title of Project: Utilizing cDNA Subtraction to Examine the Effects of MacroH2A Deletion in a Colony of Knockout Mice.
Mentor: John Pehrson
Department: Animal Biology, Veterinary Medicine

Student: Catherine Morrow
Title of Project: Factor XI Deficiency in Kerry Blue Terriers: Frequency and Impact of SINE Insertion.
Mentor: Urs Giger
Department: Clinical Studies, Philadelphia, Veterinary Medicine

Student: Diana Niculescu
Title of Project: Gene Expression in Cone Photoreceptors of Normal Dogs with Achromatopsia.
Mentor: Andras Komaromy
Department: Clinical Studies, Philadelphia, Veterinary Medicine

Student: Sharon Parker
Title of Project: Meloxicam Use in Avian Rehabilitation: Dosage Requirements and Efficacy, as Compared to Aspirin and Butorphanol.
Mentor: Erica Miller, Lisa Murphy
Department: Clinical Studies, Philadelphia, Veterinary Medicine, and Pathobiology, Veterinary Medicine

Student: Maria Raymond
Title of Project: Effects of Co-Engagement of Toll-Like Receptors (TLRs) and Complement Receptors.
Mentor: Oriol Sunyer
Department: Pathobiology, Veterinary Medicine

Student: Michael Reese
Title of Project: Assessment of Cryocapacitation and Its Relation to Fertility of Frozen Bovine Sperm.
Mentor: Ina Dobrinski
Department: Clinical Studies, New Bolton Center, Veterinary Medicine

Student: Brigid Reilly
Title of Project: Use of a Novel Yeast Two-Hybrid System to Identify Homotypic and Heterotypic Interactions of Herpes Simplex Virus Glycoproteins.
Mentor: Roselyn Eisenberg, Gary Cohen
Department: Pathobiology, Veterinary Medicine

Student:
Title of Project: Cell fate of Notochordal Cells During Late Embryonic and Postnatal Life in Rodent Model.
Mentor: Tom Schaer
Department: Clinical Studies, New Bolton Center, Veterinary Medicine

Student: Miriam Sadek
Title of Project: Role of Mitochondrial Stress Signaling in the Pancreatic Tumor Invasion.
Mentor: Narayan Avadhani, Gopa Biswas
Department: Animal Biology, Veterinary Medicine

Student: Lindsay Thalheim
Title of Project: Transcriptional Regulation of the Intra-S-Phase Regulator of CDC7 in Human Myeloid Leukemic Cells: A New Downstream Target of the C-Myb Protooncogene.
Mentor: Alan Gewirtz
Department: Hematology-Oncology, Medicine

Student: Amanda Theodore
Title of Project: The Role of Regulatory T Cell Function in Leishmania mexicana Infection.
Mentor: Phil Scott
Department: Pathobiology, Veterinary Medicine

Student: Rachel Toaff-Rosenstein
Title of Project: Evaluation of the Insulin Gene and DLA-DRB2 Alleles as Genetic Markers for Diabetes Mellitus in Samoyed and Australian Terrier Dogs.
Mentor: Rebecka Hess, Paula Henthorn
Department: Clinical Studies, Philadelphia, Veterinary Medicine

Student: Angharad Knight Waite
Title of Project: Molecular Cloning of Canine OX40L and Functional Evaluation of its Co-Stimulatory Effects on Canine T Cell Subsets.
Mentor: Nicola Mason
Department: Clinical Studies, Philadelphia, Veterinary Medicine

Student: Connie Yeh
Title of Project: Functional Study of the Insulin Receptor Kinase IRK-1 from Strongyloides stercoralis Using Caenorhabditis elegans as a Genetic Surrogate.
Mentor: James Lok
Department: Pathobiology, Veterinary Medicine

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Funded Projects - 2005

Student: Donniel Astor
Title of Project: Induction of the Unfolded Protein Response in Flies with Long-Term Intermittent Hypoxia
Mentor: Cindy Otto
Department: Clinical Studies, Philadelphia , Veterinary Medicine

Student: Lisa Berman
Title of Project: Characterization of the Novel Canine and Feline Erythrocyte Antigens Dal and Mik
Mentor: Urs Giger
Department: Clinical Studies, Philadelphia, Veterinary Medicine

Student: Megan Brace
Title of Project: A Mathematical Model for the Transmission Dynamics and Control of Hepatitis B Virus Infection in Wild Chimpanzees (Pan Troglodytes)
Mentor: Gary Smith
Department: Clinical Studies, New Bolton Center, Veterinary Medicine

Student: Amy Brazil
Title of Project: Impact of Stress and Dietary High Fat on Learning and Memory
Mentor: Tracy Bale
Department: Animal Biology, Veterinary Medicine

Student: Janik Gasiorowski
Title of Project: Electrotransfer of Plasmid DNA in the Equine Flexor Tendon
Mentor: Dean Richardson
Department: Clinical Studies, New Bolton Center, Veterinary Medicine

Student: Kelly Giunta
Title of Project: Generation and Characterization of Equine Embryonic Stem Cell Lines
Mentor: John McLaughlin
Department: Clinical Studies, New Bolton Center, Veterinary Medicine

Student: Ryan Gorman
Title of Project: Development of Real-Time 16S rRNA Gene Polymerase Chain Reaction Assay to Diagnose Septic Peritonitis
Mentor: Shelley Rankin
Department: Clinical Studies, Philadelphia, Veterinary Medicine

Student: Asal Homayouni
Title of Project: The Role of TSR Proteins in Myc-Overexpressed Cells of Mouse Colon Cancer
Mentor: Andrei Thomas-Tikhonenko
Department: Pathobiology, Veterinary Medicine

Student: Tyler Hotaling
Title of Project: Molecular Characterization of Staphylococcus aureus Strains from the University of Pennsylvania and the University of Delaware Heifers Before, During and After Co-Mingling
Mentor: Shelley Rankin, Charles Benson, Mike Kristula
Department: Clinical Studies, Philadelphia, Veterinary Medicine

Student: Ann Klocke
Title of Project: Molecular and Cellular Regulation of Boar Sperm Motility
Mentor: Regina Turner
Department: Clinical Studies, New Bolton Center, Veterinary Medicine

Student: Jennifer Magilton
Title of Project: Effect of PaO2 Oscillations on the Correlation of Non-Invasive Measurements of SpO2 with Direct Measurements of PaO2 in Mechanically Ventilated Patients
Mentor: Rebecca Syring
Department: Clinical Studies, Philadelphia, Veterinary Medicine

Student: Isaac Maxmen
Title of Project: Identification and Typing of the Ehlers-Danlos Syndrome in the Canine Model
Mentor: Margaret Casal
Department: Clinical Studies, Philadelphia, Veterinary Medicine

Student: Emily Miedel
Title of Project: Role of Astrocytes in Resistance to Toxoplasic Encephalitis
Mentor: Chris Hunter
Department: Pathobiology, Veterinary Medicine

Student: Jennifer Scheidt
Title of Project: Characterization and Identification of the Disease-Causing Mutation of Lupoid Dermatosis in the German Shorthaired Pointer
Mentor: Margaret Casal
Department: Clinical Studies, Philadelphia, Veterinary Medicine

Student: Lindsay Thalheim
Title of Project: Myb Modulation of CDC7 Expression in Hematopoietic Cells
Mentor: Alan Gewirtz
Department: Medicine and Pathology, Medicine

Student: LeAndra Thompson
Title of Project: The Effects of Cytoplasmic Dynein Disruption on the De-Stabilization of the Mammalian Neuromuscular Junction
Mentor: Erika Holzbaur
Department: Physiology, Medicine

Student: Tracy Zeldis
Title of Project: Defining the Effects of Specific NEMO Mutations on Pro-Inflammatory NF-?B Activation
Mentor: Michael May
Department: Animal Biology, Veterinary Medicine

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Funded Projects - 2004

Student: Jeffrey Burdick
Title of Project: Reparative vs. Regenerative Tendon Healing in an Animal Model.
Mentor: Louis J. Soslowsky
Department: Bioengineering, School of Medicine

Student: Cynthia Clendenin
Title of Project: Identification of Genes Causing Lupoid Dermatosis in the German Shorthaired Pointer.
Mentors: Paula Henthorn, Margaret Casal
Department: Clinical Studies, Philadelphia, Veterinary Medicine

Student: Modesty Dallmeyer
Title of Project: Improving Sow Fertility Through Novel Semen Extender Components.
Mentor: Ina Dobrinski
Department: Clinical Studies, New Bolton Center, Veterinary Medicine

Student: Eva Furrow
Title of Project: How Does Vincristine Cause Neuropathy in Normal and Mutant Mice?
Mentor: Christiane Massicotte
Department: Clinical Studies, Philadelphia, Veterinary Medicine

Student: Rachael Joseph
Title of Project: The Role of B-Cell Transcription Factors, EBF and Pax5, in the Spontaneous Transformation of B lymphoma Cells to Myeloid Cells In Vitro.
Mentor: Michael Atchison
Department: Animal Biology, Philadelphia, Veterinary Medicine

Student: Lyndsey Larson
Title of Project: Mitochondrial Targeting of Amyloid Protein in Feline Islet Amyloidosis.
Mentor: Narayan Avadhani
Department: Animal Biology, Philadelphia, Veterinary Medicine

Student: Maureen Luschini
Title of Project: Do Cats HarborBorrelia burgdorferi and Is Its Presence linked to Lyme Disease Pathology?
Mentor: Thomas Nolan
Department: Pathobiology, Philadelphia, Veterinary Medicine

Student: Grace Anne Mengel
Title of Project: Is There a Role for T-type Calcium Channels in Sperm Motility?
Mentor: Regina Turner
Department: Clinical Studies, New Bolton Center, Veterinary Medicine

Student: Craig Meredith
Title of Project: Changes in Primary Hemostasis and Clot Formation in Dogs Treated with Cycooxygenase Inhibitors with Varying Isoenzyme Selectivity.
Mentors: Cynthia Otto, Beth Callan, Benjamin Brainard
Department: Clinical Studies, Philadelphia, Veterinary Medicine

Student: Catalina Montealagre
Title of Project: Vascular Endothelial Growth Factor Levels and Activity in Conjunction with Multifrequency Bioimpendance Analysis in Critically Ill Dogs.
Mentor: Cynthia Otto
Department: Clinical Studies, Philadelphia, Veterinary Medicine

Student: Heidi L. Reesnick
Title of Project: Detection of Recombinant Human Erythropoietin (rhEPO) and Analysis of Performance Indices Following rhEPO Administration in Racehorses.
Mentor: Eric Birks
Department: Clinical Studies, New Bolton Center, Veterinary Medicine

Student: Scott Roberts
Title of Project: Identification of Leukocidin Genes in Stphylococcus schleiferi Subspecies coagulans by Real-Time Polymerase Chain Reaction.
Mentor: Shelley Rankin
Department: Pathobiology, New Bolton Center, Veterinary Medicine

Student: Sara Rybolt
Title of Project: Pharmacokinetic Study of Non-Steroidal Anti-Inflammatory Drugs in Rehabilitation Birds.
Mentor: Robert Poppenga
Department: Pathobiology, New Bolton Center, Veterinary Medicine

Student: Heather Simon
Title of Project: The In Vitro Effects of Shape on Elution Characteristics from Gentamicin-Impregnated PMMA.
Mentors: Amy Kapatkin, Karen Rosenthal, Avery Bennett, Robert Poppenga Department: Clinical Studies, Philadelphia, Veterinary Medicine

Student: Rebecca Spivack
Title of Project: Effects of Cyclical Lung recruitment and Pa O2 Oscillations on Multiple Organ Dysfunction.
Mentors: Rebecca Syring, Cynthia Otto
Department: Clinical Studies, Philadelphia, Veterinary Medicine

Student: Kirsten Steele
Title of Project: Mechanisms of the Anti-Tumor Effect of Tumor Necrosis Factor (TNF) in Pre-Clinical Models.
Mentor: Douglas Fraker
Department: Surgical Oncology, School of Medicine

Student: Heather Wall
Title of Project: Modafinil and msrA Expression in Drosophila.
Mentor: Joan Hendricks
Department: Clinical Studies, Philadelphia, Veterinary Medicine


Student: Koranda Wallace
Title of Project: Immunohistochemical Investigation of Laminin 5 and Other Basement Membrane Zone Proteins in a Litter of Labrador Retrievers with Inherited Epidermolysis Bullosa.
Mentor: Margaret Casal
Department: Clinical Studies, Philadelphia, Veterinary Medicine

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Funded Projects - 2003

Student: Greg Arbitter
Title of Project: Kinetic Gait Analysis of Healthy Dogs on Various Surfaces.
Mentor: Amy Kapatkin
Department: Clinical Studies, Philadelphia, Veterinary Medicine

Student: Jennifer Ascano
Title of Project: A Direct Interaction Between Dynein Intermediate Chain and Neurofilament subunits M and L May Mediate Retrograde Trafficking of Neurofilaments.
Mentor: Erika Holzbaur
Department: Physiology, School of Medicine

Student: Jessica Bertout
Title of Project: Steroid Regulation of EMP2 Localization and Expression in Human Endometrial Cells.
Mentor: Carmen Williams
Department: OB/GYN

Student: Alexandre Daley
Title of Project: Anchoring of CA 2+ Signaling Pathway in the Sperm Flagellum.
Mentor: Regina Turner
Department: Clinical Studies, New Bolton Center, Veterinary Medicine

Student: Keira Geithman
Title of Project: Canine Parvovirus: A Case-Control Study on Factors Influencing Disease Incidence.
Mentor: Gary Smith
Department: Clinical Studies, New Bolton Center, Veterinary Medicine

Student: Jennifer Kim
Title of Project: Drug Metabolism by Recominant Cytochrome P450 2D6
Mentor: Narayan Avadhani, Gary Smith
Department: Animal Biology, Veterinary Medicine

Student: Maureen Luschini
Title of Project: Prevalence of Ehrlichia canis, Anaplasma phagocytophila, and Bartonella spp. In Dogs Determined by PCR and Serology.
Mentor: Shelley Rankin
Department: Clinical Studies, Philadelphia, Veterinary Medicine

Student: Kari Lyon
Title of Project: Gait Analysis in Dynamitin Mice: Correlation with Early Axonal Transport Defects.
Mentor: Erika Holzbaur
Department: Physiology, School of Medicine

Student: Xuan Pan
Title of Project: Temporal Requirements of YY1 Expression for PcG-Dependent Transcriptional Repression.
Mentor: Michael Atchison
Department: Animal Biology, Veterinary Medicine

Student: Lora Perl
Title of Project: Comparison of Mouse and Cat Oct4.
Mentor: Hans Scholer
Department: Animal Biology, New Bolton Center, Veterinary Medicine

Student: Zoe Ramagnano
Title of Project: An In Vitro Study on the Role of CD46 in the Differentiation and Propagation of Murine Tr1 Cells.
Mentor: Philip Scott and Oriol Sunyer
Department: Pathobiology, Veterinary Medicine

Student: Ellen Rickey
Title of Project: Strain Characteristics of the Equine Cruciate Ligaments.
Mentor: David Nunamaker
Department: Clinical Studies, New Bolton Center, Veterinary Medicine

Student: Jennifer Stevens
Title of Project: Development of a Rapid Dot Blot Immunoassay for the Detection of Salmonella enterica Serotype Newport.
Mentor: Helen Aceto and Shelley Rankin
Department: Clinical Studies, New Bolton Center, Veterinary Medicine

Student: Alanna Toll
Title of Project: Lymphocyte/Enterocyte Interactions in Canine Inflammatory Bowel Disease.
Mentor: Robert Washabau
Department: Clinical Studies, Philadelphia, Veterinary Medicine

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Funded Projects - 2002

Student: Beth Appleman
Title of Project: Characterization of the Altered Glycosaminoglycans and Proteoglycans in Collagen X Transgenic and Null Mice.
Mentor: Olena Jacenko
Department: Animal Biology, Veterinary Medicine

Student: Diana Chang
Title of Project: Regulation of Glut3, a Glucose Transporter, During Sperm Capacitation and Germ Cell Development
Mentor: George Gerton
Department: OB/GYN

Student: Rachel Cianciolo
Title of Project: Dynamics of Membrane Rafts During Sperm Capacitation.
Mentor: Carmen Williams
Department: OB/GYN

Student: Daniel Clayton
Title of Project: Mechanisms of Immunopathology in Canine Inflammatory Bowel Disease.
Mentor: Robert Washabau
Department: Clinical Studies, Philadelphia, Veterinary Medicine

Student: Kathy Heym
Title of Project: Expression Optimization of a Fish DNA Vaccine against Infectious Hematopoietic Necrosis Virus
Mentor: Oriol Sunyer
Department: Pathobiology, Veterinary Medicine

Student: Melissa Java
Title of Project: The Effects of pO 2 Oscillations on the Production of Cytokines.
Mentor: Cindy Otto
Department: Clinical Studies, Philadelphia, Veterinary Medicine

Student: Kimberly Kovath
Title of Project: The Effects of Intermittent Hypoxia on Coagulation and Inflammatory Mediators in Mice.
Mentor: Sigrid Veasey
Department: Neurosciences, School of Medicine

Student: Rebecca Linke
Title of Project: Demonstration of Functional Competence in Pig Sperm from Testis Xenographs.
Mentor: Ina Dobrinski
Department: Clinical Studies, New Bolton Center, Veterinary Medicine

Student: Jennifer Luff
Title of Project: The Spatial Dynamics of West Nile Virus Infection in Birds in the USA.
Mentor: Gary Smith
Department: Clinical Studies, New Bolton Center, Veterinary Medicine

Student: Lauren May
Title of Project: Role of Mitochondrial Stress Signaling in Tumor Progression and Invasion.
Mentor: Narayan Avadhani, Gary Smith
Department: Animal Biology, Veterinary Medicine

Student: James Rhodes
Title of Project: Sequence Generation and Analysis of Canine ED1 and NEMO: Two Suspect Genes in Canine X-linked Hypohidrotic Ectodermal Dysplasia.
Mentor: Margaret Casal
Department: Clinical Studies, Philadelphia, Veterinary Medicine

Student: John Rossi
Title of Project: The Role of Platelets in Circulating Tumor Cell Survival and Proliferation in Pulmonary Metastasis.
Mentor: Ruth Muschel
Department: Psychology, School of Medicine

Student: Kelli Russel
Title of Project: Feline Hyperthyroidism: Determination of Differential Activation of G s a and G i a Proteins in Response to Thyrotropin Treatment.
Mentor: Cindy Ward
Department: Clinical Studies, Philadelphia, Veterinary Medicine

Student: Sara Ryan
Title of Project: Immune Function in Canine X-linked Hypohidrotic Ectodermal Dysplasia.
Mentor: Margaret Casal
Department: Clinical Studies, Philadelphia, Veterinary Medicine

Student: Todd Strochlic
Title of Project: A Possible Nuclear Role for a Msb3p-Tci1p Complex in the Development of Cell Polarity.
Mentor: Erfei Bi
Department: Cell and Developmental Biology, School of Medicine

Student: Kathryn Vickery
Title of Project: An In Vitro and In Vivo Study on the Role of Various Cytokines in Promoting IL-10 Producing Cells in Leishmania major Infections.
Mentor: Philip Scott
Department: Pathobiology, Veterinary Medicine

Student: Fred Wininger
Title of Project: Biomechanical Optimization of Dynamic Compression Plate Fixation for Arthrodesis of the Carpal Joint in the Dog.
Mentor: Gail Smith
Department: Clinical Studies, Philadelphia, Veterinary Medicine

Student: Steven Zedler
Title of Project: AAV Transduction of Condrocytes in Equine Cartilage Explant Culture.
Mentor: Dean Richardson
Department: Clinical Studies, New Bolton Center, Veterinary Medicine

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Funded Projects - 2001

Student: Beth Appleman
Title of Project: Characterization of the Altered Glycosaminoglycans and Proteoglycans in Collagen X Transgenic and Null Mice.
Mentor: Olena Jacenko
Department: Animal Biology, Veterinary Medicine

Student: Raul Casas-Dolz
Title of Project: Differential Gene Expression in Stallions with Testicular Degeneration.
Mentor: Regina Turner
Department: Clinical Studies, New Bolton Center, Veterinary Medicine

Student: Rebecca Garabed
Title of Project: Zoopork – Prevalence of Zoonotic Pathogens in Different Housing Systems for Fattening Pigs.
Mentor: Helen Wheeler-Aceto and Shelley Rankin
Department: Clinical Studies, New Bolton Center, Veterinary Medicine

Student: Daniel Hall
Title of Project: Demonstration of Viscerotropy Within Barrington’s Nucleus in Rats.
Mentor: Richard Miselis
Department: Animal Biology, Veterinary Medicine

Student: Deborah Hirschmann
Title of Project: A Minimal Genome-Wide Scan for Patent Ductus Arteriosus (PDA) Using DNA from a Large Informative Canine Family.
Mentor: Paula Henthorn
Department: Clinical Studies, Philadelphia, Veterinary Medicine

Student: Alice Hsu
Title of Project: Endocrine Regulation of a Novel Form of Adenylyl Cyclase in the Male Reproductive Tract.
Mentor: Gregory Kopf
Department: OB-GYN, Medicine

Student: Jennifer Kaae
Title of Project: Analysis of the Immune Status in Collagen X Defective Mice.
Mentor: Olena Jacenko
Department: Animal Biology, Veterinary Medicine

Student: Colleen Kane
Title of Project: Role of NF-kB in T Cell Survival.
Mentor: Chris Hunter
Department: Pathobiology, Veterinary Medicine

Student: Kimberly Kovath
Title of Project: An Evaluation of Thromboelastography in Dogs with Immune-Mediated Hemolytic Anemia.
Mentor: Cindy Otto
Department: Clinical Studies, Philadelphia, Veterinary Medicine

Student: Emily Kupprion
Title of Project: Coal Flyash as Dairy Bedding Amendments for Mastitis Bacteria Control.
Mentor: Zhengxia Dou
Department: Clinical Studies, New Bolton Center, Veterinary Medicine

Student: Chung Lee
Title of Project: Mechanism of E47-Pip DNA Binding and Transcriptional Synergy.
Mentor: Michael Atchison
Department: Animal Biology, Veterinary Medicine

Student: Mark Lopez
Title of Project: The Anatomy and Function of Specific Sensory Neurons in Three Species of Parasitic Nematodes and One Free-Living Nematode Species.
Mentor: Gerry Schad
Department: Pathobiology, Veterinary Medicine

Student: Julie McDade
Title of Project: The Effect of Fimbriae Expression Salmonella enteric Serovar Enteritidis on Heeterophil and Monocyte Response in Chickens.
Mentor: Dieter Schifferli and Wil Weber
Department: Pathobiology, Veterinary Medicine

Student: Anne Skope
Title of Project: Cloning and Expression of Non-Human Primate DC-SIGNR.
Mentor: Robert Doms
Department: Pathology, Medicine

Student: Amy Snedaker
Title of Project: Investigation of the Developmental Potential of Porcine Spermatogenic Cells in Organ Culture and Tissue Grafts.
Mentor: Ina Dobrinski
Department: Clinical Studies, New Bolton Center, Veterinary Medicine

Student: Todd Strochlic
Title of Project: Analysis of the Interaction Between PLAC-24 and CLIP-115.
Mentor: Erika Holzbaur
Department: Animal Biology, Veterinary Medicine

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Funded Projects - 2000

Student: Brady Beale
Title of Project: Improving fertility of cryopreserved canine semen.
Mentor: Cindy Ward
Department: Clinical Studies, Philadelphia, Veterinary Medicine

Student: Danalyn Dess
Title of Project: Role of soluble adenylyl cyclase in regulating metabolic changes during sperm capacitation.
Mentor: Stuart Moss
Department: Cell and Developmental Biology

Student: Tracy Anne Filler
Title of Project: Identification of erythrocyte pyruvate kinase deficiency in long hair Dachshund, Chihuahua, and Toy Eskimo dogs.
Mentor: Urs Giger
Department: Clinical Studies, Philadelphia, Veterinary Medicine

Student: Alfredo Geigel
Title of Project: Identification, localization, and binding specificity of trout C3b receptors.
Mentor: Oriol Sunyer
Department: Pathobiology

Student: Dan Hall
Title of Project: Generation of cDNA libraries from male germ cells in goats.
Mentor: Ina Dobrinski
Department: Clinical Studies, New Bolton Center, Veterinary Medicine

Student: Alexander Hamberg
Title of Project: Adeno-associated virus induction of alpha-L-iduronidase cDNA in Mucopolysaccharidosis I kittens.
Mentor: Mark Haskins
Department: Pathobiology

Student: Colleen Kane
Title of Project: Immunocompetence of murine fetal liver cells in mixed lymphcyte reactions.
Mentor: Margaret Casal
Department: Clinical Studies, Philadelphia, Veterinary Medicine

Student: Eric Lombardini
Title of Project: Zoonotic transmission of helminth parasitism from the consumption of wildlife in Bioko, Equatorial Guinea
Mentor: Gerry Schad
Department: Pathobiology

Student: Katherine Masek
Title of Project: Expression and localization of soluable adenylyl cyclase in murine oocytes.
Mentor: Carmen Williams
Department: OB/GYN

Student: Julie McDade
Title of Project: Effect of fimbriae expression in Salmonella enteritidis on heterophil and moncyte response in chickens.
Mentor: Dieter Schifferli
Department: Pathobiology

Student: Catherine McManus
Title of Project: In vitro mucosal effects of short chain fatty acids in the canine and feline colon.
Mentor: Robert Washabau
Department: Clinical Studies, Philadelphia, Veterinary Medicine

Student: Courtney North
Title of Project: Identification of Rab3 proteins involved in sperm acrosomal exocytosis.
Mentor: Cindy Ward
Department: Clinical Studies, Philadelphia, Veterinary Medicine

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Funded Projects - 1999

Student: Christine Adreani
Title of Project: The Cloning and Expression of a Functional Equine Tissue Inhibitor of Matrix Metalloproteinase - 1.
Mentor: Dr. Dean Richardson
Department: Clinical Studies, New Bolton Center, Veterinary Medicine

Student: Amy Bucher
Title of Project: Effects of Drug Therapies on Blood Flow to the Equine Hoof.
Mentor: Dr. Eric Birks
Department: Clinical Studies, New Bolton Center, Veterinary Medicine

Student: David J. Champaigne
Title of Project: Benzodiazepine Influences on Amygdalar Modulation of Sleep.
Mentor: Dr. Larry D. Sanford
Department: Animal Biology, Veterinary Medicine

Student: Catherine Cheng
Title of Project: REM-A as a Model of REM Behavior Disorder (RBD).
Mentor: Dr. Adrian Morrison
Department: Animal Biology, Veterinary Medicine

Student: Rosalind S. Chow
Title of Project: The use of reduced and oxidized glutathione levels in serum and erythrocytes as indicators of reperfusion injury following blunt vehicular trauma in dogs.
Mentor: Dr. Cynthia M. Otto
Department: Clinical Studies, Philadelphia, Veterinary Medicine

Student: Sherri S. Cokefair
Title of Project: Serum Tumor Necrosis Factor Levels in Dogs Following Blunt Vehicular Trauma.
Mentor: Dr. Cynthia Otto
Department: Clinical Studies, Philadelphia, Veterinary Medicine

Student: Jennifer W. Gschwend
Title of Project: Estimates of Heritability of Hip Scores in Golden Retrievers.
Mentor: Dr. Gail K. Smith
Department: Clinical Studies, Philadelphia, Veterinary Medicine

Student: Meryl Gupta
Title of Project: Cdc42-Responsive Elements in the Cyclin A Promoter.
Mentor: Dr. Margaret M. Chou
Department: Cell and Developmental Biology, Medicine

Student: Aspen A. Hammond
Title of Project: The Effect of Training on Bone Modulus in Thoroghbred Racehorses: A Biochemical Study.
Mentor: Dr. David Nunamaker
Department: Clinical Studies, New Bolton Center, Veterinary Medicine

Student: Kristina Lu
Title of Project: Genetic Imprinting in Androgenetic Mouse Chimeras.
Mentor: Dr. K. John McLaughlin
Department: Animal Biology, Veterinary Medicine

Student: Katherine Masek
Title of Project: Expression and Localization of Glucose Transporter Proteins in Murine Sperm and Developing Male Germ Cells.
Mentor: Prof. Gregory S. Kopf
Department: OB-GYN, Medicine

Student: Catherine M. McManus
Title of Project: Effects of Fiber Fermentation Metabolites on Feline Gastrointestinal Function: Smooth Muscle Contractility and Mucosal Transport.
Mentor: Drs. Kathryn Michel
and Robert Washabau
Department: Clinical Studies, Philadelphia, Veterinary Medicine

Student: Aliza Moldofsky
Title of Project: Health and Productivity of Dairy Cows Following Rumenocentesis: A Risk Assessment Study.
Mentor: Dr. Helen Wheeler-Aceto and Dr. James Ferguson
Department: Clinical Studies, New Bolton Center, Veterinary Medicine

Student: Robert Richardson
Title of Project: Osteonal Trajectories in Equine Cortical Bone: Relationships of Primary and Secondarty Osteons with Exercise.
Mentor: Dr. David Nunamaker
Department: Clinical Studies, New Bolton Center, Veterinary Medicine

Student: Katherine Wentworth
Title of Project: The Effects of Cryopreservation on Hyaluronidase Activity in Equine Sperm.
Mentor: Dr. Stuart Meyers
Department: Clinical Studies, New Bolton Center, Veterinary Medicine

Student: Steve West
Title of Project: Immunomagnetic Separation (IMS) as a Method for Isolating Mycobacterium paratuberculosis (M.ptb) from Ruminant Fecal Samples.
Mentor: Dr. Robert Whitlock
Department: Clinical Studies, New Bolton Center, Veterinary Medicine