James MacLeod
Professor of Veterinary Science
John S. and Elizabeth A. Knight Chair
Director, Equine Initiative
Unviersity of Kentucky
VMD: 1984
PhD: 1990
Graduate Group: Pathology
Thesis Topic: Hormonal regulation of hepatic P450 monooxygenases
Dr. MacLeod's laboratory studies biological and biomedical aspects of the musculoskeletal system, with an emphasis on the growth and maturation of articular cartilage, the development of osteoarthritis, repair of cartilage lesions, and the effects of intra-articular glucocorticoid medications on chrondrocyte function. Experiments are conducted primarily on a cellular and molecular level. In addition to articular cartilage, recent projects have been initiated on tendons, cervical stenosis myelopathy, and broad analyses of the equine transcriptome.