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|
Contents
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Shelf Life
|
Preparation
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| Fresh whole blood (FWB) |
RBC, plasma proteins, all coagulation factors, WBC, platelets (approx. Hct 40%)
|
Less than 8 hours
after initial collection |
Use immediately following collection (refrigeration compromises platelet function) |
Stored whole blood (SWB)
|
RBC, plasma proteins (approx. Hct 40%) |
Greater than 8 hours
old & up to 35 days
(dependent on anticoagulant-preservative solution used); refrigerate at 1-6°C |
Allow to come to room temp (temps exceeding 37ºC will result in hemolysis & bacterial proliferation)
|
| Packed red blood cells (PRBC) |
RBC (approx. Hct 80%), reduced plasma |
Dependent on anticoagulant-preservative
solution used;
refrigerate at 1-6° C |
Allow to come to room temp (temps exceeding 37°C will result in hemolysis & bacterial proliferation); may reconstitute with 0.9% NaCl prior to administration
|
| Packed red blood cells (PRBC), adenine-saline added |
RBC (approx. Hct
60%), reduced plasma, 100 ml additive solution |
30-35 days;
refrigerate at 1-6° C |
Allow to come to room temp (temps exceeding 37°C will result in hemolysis & bacterial proliferation)
|
| Platelet-rich plasma/platelet concentrate |
Platelets, few RBC and WBC, some plasma |
5 days at 22°C;
intermittent agitation
required |
Should administer immediately following collection and preparation
|
| Fresh frozen plasma (FFP) |
Plasma, albumin, all coagulation factors |
12 months frozen
at -20°C or below |
Thaw in 37°C warm water bath (temps exceeding 37°C will result in protein denaturation & bacterial proliferation)
|
| Frozen plasma (FP) |
Plasma, albumin, stable coagulation factors |
5 years frozen
at -20°C or below |
Thaw in 37°C warm water bath (temps exceeding 37°C will result in protein denaturation & bacterial proliferation)
|
Cryoprecipitate
(CRYO) |
Factor VIII, vWF, fibrinogen, fibronectin |
12 months frozen
at -20°C or below |
Thaw in 37°C warm water bath (temps exceeding 37°C will result in protein denaturation & bacterial proliferation) |