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New Bolton Center
Research Laboratories & Centers


Our faculty at New Bolton Center are engaged in ongoing groundbreaking research in topics ranging from Laminitis to Botulism. Here are examples of research centers and laboratories and the projects being investigated at New Bolton Center.

Center for Animal Health and Productivity (CAHP)

  • The Center for Animal Health and Productivity (CAHP) was established in 1986 to implement teaching, research and service programs directed toward the improvement of health and productivity in food animal herds and flocks. These programs involve an integrated approach employing expertise in disciplines such as clinical nutrition, reproduction, health economics and computer science in addition to conventional specialties in veterinary medicine. The focus of the CAHP is the maintenance of physical and economic health in the whole animal population rather than clinical treatment of individual sick animals.

    Our Mission: To develop, communicate and apply knowledge needed for improvement of the health and productivity of food animal populations.

    History
    The Center for Animal Health and Productivity (CAHP) was established in 1986 to implement teaching, research and service programs directed toward the improvement of health and productivity in food animal herds and flocks. These programs involve an integrated approach employing expertise in disciplines such as clinical nutrition, reproduction, health economics and computer science in addition to conventional specialties in veterinary medicine. The focus of the CAHP is the maintenance of physical and economic health in the whole animal population rather than clinical treatment of individual sick animals.

    Read More About The Center for Animal Health and Productivity (CAHP)

Comparative Orthopaedic Research Laboratory

  • Penn Vet, surgery at New Bolton CenterThe Translational Services Program (non-clinical and clinical) is one of the core capabilities of the Penn Vet CORL Group in the Section of Surgery, Department of Clinical Studies New Bolton Center. It is comprised of the Surgical Models Services, Non-Clinical (GLP) and Clinical (VICH-GL9) Trials Design and Management, Imaging and Histological Services.

    The focus of the Translational Services Program is directed towards supporting product development at any level providing a “one-stop-and-shop” R&D platform within and outside the University of Pennsylvania biomedical community. This program has the skills, experience and knowledge to assist researchers, product developers and project managers in a modular manner starting with project design and ending with data analysis, study audits, final report, regulatory filings and publication. The main partners for collaborative projects are scientists from the greater Philadelphia area, national and international clinicians, material scientists and industrial partners. The investigations are typically of an applied nature and are conducted under a research agreement or a fee for services arrangement.

    The PENN VET CORL Group in its current make-up has been a partner in pivotal studies for 10 years, assisting device manufacturers in the successful translation of novel therapeutic interventions and its submission of regulatory filings.

    Read More About The Comparative Orthopaedic Research Laboratory

Swine Teaching and Research Unit

  • Penn Vet's Swine facilityToday the US swine industry finds itself confronted with rapidly changing public opinion and policy on how gestating sows should be housed. Penn Vet is uniquely positioned to provide the industry with relevant scientific data collected from this living laboratory.
    Read More About The Swine Teaching and Research Unit

ASMG Laboratory - Microbial Genomics

  • The Agricultural ASMG Lab, New Bolton CenterSystems and Microbial Genomics Laboratory (ASMG Laboratory) was established to support Dr. Dou and Dr. Pitta in their research endeavors.  

    Dr. Pitta is the ruminant nutrition and microbiologist at the Center for Animal Health and Productivity (CAHP), New Bolton Center, University of Pennsylvania.

    Microbial Genomics

    Research in the Microbial Genomics section of the ASMG lab focuses primarily on the New Bolton Center, ASMG Lab-Microbial Genomicsgut microbial composition of ruminants, utilizing both culture-based and advanced molecular methodologies. The alimentary tract of a ruminant is colonized by millions of microbes living in a symbiotic relationship with the host. Therefore, knowledge of the microbial composition of the entire gut can provide insights into improving the overall health and productivity of the animal.

    Microbiology Component

    The recent advent of next generation sequencers has greatly enhanced the ability to explore community microbial populations. The ASMG lab has the capabilities to perform metagenomic studies including sample preparation, genomic DNA extraction and generating 16S amplicon libraries for sequencing on next generation platforms. The sequenced data is analyzed at the ASMG laboratory utilizing the appropriate bioinformatics tools for data interpretation. The lab is in the process of streamlining the protocols for generating 18S libraries for protozoa and fungal communities.

    Read More About The ASMG Laboratory - Microbial Genomics

Reference Andrology Laboratory

  • The Reference Andrology Laboratory provides complete testing of neat, cooled and frozen-thawed semen from mammalian and avian species. The primary purpose of these services is to aid practitioners in their differential diagnosis of individual/herd/flock reproductive problems.

    These services are also frequently used by practitioners and studs as a third-party quality control component in an ongoing stud auditing process.

    The laboratory strives to perform objective, validated techniques for assessing samples for the basic spermiogram parameters of sample volume, motility, morphology, and concentration. With advanced notification, we will also try to accommodate requests for supplemental assessment techniques on sperm subcellular structures. We also offer semen extender analysis and microbiological testing of the extended semen product and purified water used in extenders.
    Read More About The Reference Andrology Laboratory

Marshak Dairy

  • Marshak Dairy, New Bolton CenterThe Marshak Dairy is named in honor of Robert Marshak, the ninth dean of the School of Veterinary Medicine whose support was instrumental in establishing the farm. Built in 1996, the greenhouse dairy was the first of its kind and was recognized as a dairy of distinction in 1998. The greenhouse design uses natural lighting and excellent ventilation within the barn to promote a healthy environment for the cows.

    The Marshak Dairy provides an easily accessible working dairy farm for research trials. In addition, the Dairy serves as a laboratory for teaching students on topics related to cow healthcare, preventive medicine, nutrition and food safety.

    Read More About The Marshak Dairy

Equine Pharmacology Laboratory

  • Equine Pharmacology at New Bolton CenterIn 2006, Dr. Lawrence R. Soma, VMD, and professor of Large Animal Medicine at New Bolton Center, and Dr. Cornelius E. Uboh, director of the Pennsylvania Equine Toxicology and Research Laboratory (PETRL) in West Chester, PA, and their respective teams at Penn Vet and PETRL became the first research group in the world to develop and establish a method for confirming blood-doping agents in racehorse serum.

    Previously only the antibodies caused by the drug, not the drug itself, were detectable in the blood. Used in human and small animal veterinary medicine to treat conditions that produce anemia such as cancer and renal disease, erythropoetin (EPO) is a natural hormone protein produced in the kidneys that stimulates red blood cell production. Recombinant human eythropoietin (rhEPO) and darbepoetin-alfa (DPO) are genetically engineered versions of EPO.

    Read More About The Equine Pharmacology Laboratory