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| Qualifications |
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1988: D.V.M. |
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| Memberships |
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- German Veterinary Medical Association - German Society of Experimental and Clinical Pharmacology and Toxicology - International Anesthesia Research Society - German Society of Equine Medicine - German Veterinary Medical Society - European College of Veterinary Pharmacology and Toxicology (ECVPT) - American College of Veterinary Anesthesiologists (ACVA) - International Veterinary Academy of Animal Pain Management (IVAPM) - The Shock Society |
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| Clinical Interests |
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- Anesthesia of large animals, especially horses - Cardiopulmonary function in the horse under anesthesia and during mechanical ventilation - Balanced anesthesia/analgesia in the horse - Pain treatment in large animals, especially horses |
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| Research Interests |
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| - Pharmacology & rheology of hemoglobin-based oxygen carriers (HBOCs or blood substitutes) - Microcirculation and tissue oxygenation - Hemorrhagic shock - Pharmacology of new anesthetics |
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| Selected Publications |
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| (Last 3 years)
1.Chan FP, Jahr JS, Driessen B, Daunt DA, Li KCP (2001) Validation of MR in-vivo measurement of oxygen saturation after resuscitation with a hemoglobin-based oxygen carrier in a rabbit model. Acad Radiol 8:583-590 2.Driessen B, Jahr JS, Lurie F, Gunther RA (2001) Inadequacy of low-volume resuscitation with hemoglobin-based oxygen carrier Hemoglobin glutamer-200 (bovine) in canine hypovolemia. J Vet Pharmacol Therap 24:61-71 3.Jahr JS, Driessen B, Lurie F, Tang Z, Louie RF, Kost G (2001) Oxygen saturation measurements in canine blood containing hemoglobin glutamer-200 (bovine): in-vitro validation of the NOVA CO-Oximeter. Vet Clin Path 30:39-45 4.Jahr JS, Lurie F, Xi S, Golkaryeh MS, Kuznetsova OA, Kullar R, Driessen B (2001) A novel approach to measuring circulating blood volume: the use of a hemoglobin-based oxygen carrier in a rabbit model. Anesth Analg 92:609-614 5.Driessen B, Jahr JS, Lurie F, Griffey SM, Gunther RA (2001) Effects of haemoglobin-based oxygen carrier Hemoglobin glutamer-200 (bovine) on intestinal perfusion and oxygenation in a canine hypovolaemia model. Br J Anaesth 86:683-692 6.Cheung ATW, Jahr JS, Driessen B, Duong PL, Chew JT, Chan MS, Lurie F, Golkaryeh MS, Kullar RK, Gunther RA (2001) The effects of a hemoglobin-based oxygen carrier (Hemoglobin glutamer-200 bovine) on the microcirculation in a canine hypovolemia model: a non-invasive computer-assisted intravital microscopy study. Anesth Analg 93:832-838 7.Jahr JS, Lurie F, Driessen B, Davis JA, Gosselin R, Gunther RA (2002) The HemoCue®, a point of care B-hemoglobin photometer, measures hemoglobin concentrations accurately when mixed in vitro with canine plasma and three hemoglobin-based oxygen carriers (HBOC). Can J Anaesth 49:243-248 8.Jahr JS, Lurie F, Driessen B (2002) The novel HemoCue® plasma/low hemoglobin system accurately measures low concentrations of three different hemoglobin-based oxygen carriers (HBOC) in plasma: Hemoglobin glutamer-200 (bovine) (Oxyglobin®), Hemoglobin glutamer-250 (bovine) (Hemopure®), and Hemoglobin-raffimer (HemolinkTM). Anesth Analg 95:870-873 9.Lurie F, Jahr JS, Driessen B (2002) Changes in circulating blood and plasma volume after hemoglobin-based oxygen carrier infusion and additional infusion of colloid solutions. AJT 9: 425-430 10.Driessen B, Zarucco L, Steffey EP, McCullough C, Del Piero F, Melton L, Puschner B, Stover SM (2002) Serum fluoride concentrations, biochemical and histopathological changes associated with prolonged sevoflurane anaesthesia in horses. J Vet Med A 49:337-347 11.Cheung ATW, Jahr JS, Duong PL, Driessen B, Gunther RA (2002) A quantitative study on microvascular changes sin hypovolemia and resuscitation. In: The microcirculation and vascular biology. Eds. Tooke J, Shore A, Whatmore J, Medimond Inc., Bologna, Italy, pp165-168 12.Zarucco L, Swanstrom MS, Driessen B, Hawkins D, Hubbard M, Steffey EP, Stover SM (2003) An in vivo equine forelimb limb model for short-term recording of peak isometric force in the superficial and deep digital flexor muscles. Vet Surg 32:439-450 13.Driessen B, Jahr JS, Lurie F, Golkaryeh M, Gunther RA (2003) Arterial oxygenation and oxygen delivery after hemoglobin-based oxygen carrier infusion in canine hypovolemic shock: a dose-response study. Crit Care Med: 31: 1771-1779 14.Lurie F, Driessen B, Jahr JS, Reynoso R, Gunther RA (2003) Validity of arterial and mixed venous oxygen saturation measurements in a canine hemorrhage model after resuscitation with varying concentrations of Hemoglobin-based Oxygen Carrier (HBOC). Anesth Analg 96: 46-50 15.Khan AK, Jahr JS, Nesargi S, Rothenberg SJ, Tang Z, Herrmann K, Louie R, Manalo MA, Reynoso R, Gunther RA, Kost GJ, Driessen B (2003) Does lead interfere with hemoglobin-based oxygen carrier (HBOC) function: lead levels in three currently tested HBOCs, and oxyhemoglobin dissociation with HBOCs and/or bovine blood with varying lead levels. Anesth Analg 96: 1813-1820 16.Jahr JS, Lurie F, Driessen B, Tang Z, Louie RF, Kost G (2003) Validation of the oxygen saturation measurements in a canine model of hemoglobin-based oxygen carrier (HBOC) infusion. AJT 10:21-28. 17.Swanstrom MS, Zarucco L, Stover SM, Hubbard M, Hawkins D, Driessen B, Steffey EP (2004) In vivo passive and active mechanical properties of the superficial and deep digital flexor muscles in the Thoroughbred equine forelimb. J Biomech: in print 18.Guan F, Uboh C, Soma L, Luo Y, Driessen B (2004) Unique tryptic peptides specific for bovine and human hemoglobin in the detection and confirmation of hemoglobin-based oxygen carriers Anal Chem: in print 19.Guan F, Uboh C, Soma L, Luo Y, Jahr JS, Driessen B (2004) Confirmation and quantification of Oxyglobin®, Hemopure® and Hemolink™ in equine and human plasma by hyphenated liquid chromatography tandem mass spectrometry. Anal Chem: in print 20.Cheung ATW, Driessen B, Jahr JS, Duong PL, Ramanujam S, Chen PCY, Gunther RA (2004) Blood substitute resuscitation as a treatment modality for moderate hypovolemia. Art Cells, Blood Subs And Immob Biotech 32: 189-207 21.Osgood SL Jahr JS, Desai P, Tsukamoto J, Driessen B (2004) Does Methemoglobin from oxidized HBOC (Hemoglobin glutamer-200) interfere with lactate measurement (YSI 2700 biochemistry analyzer)? Anesth Analg: in print 22.Jahr JS, Osgood SL, Rothenberg SJ, Steien E, Li QL, Bezdikian V, Butch ATW, Gunther RA, Cheung AT, Driessen B. (2004) Lactate measurement interference by hemoglobin-based oxygen carriers (Oxyglobin®, Hemopure®, and Hemolink™). Anesth Analg: in print 23.Burns PA, Driessen B, Boston R, Gunther RA (2004) Accuracy of a third (Dolphin Voyager) versus first generation pulse oximeter (Nellcor N-180) in predicting arterial oxygen saturation and pulse rate in the anesthetized dog. Vet Anesth Analg: submitted 24.Driessen B, Nann L, Benton R, Boston R (2004) Sevoflurane anesthetized horses are likely to require less hemodynamic support with dobutamine than isoflurane anesthetized horses. Vet Anesth Analg: submitted 25.Driessen B, Lurie F, Jahr JS, Gunther RA (2004) Effects of isovolemic resuscitation with hemoglobin-based oxygen carrier Hemoglobin glutamer-200 (bovine) on mesenteric perfusion and oxygenation in a canine model of hemorrhagic shock: a comparison with 6% hetastarch solution and shed blood: Vet Anesth Analg: submitted 26.Jahr JS, Lurie F, Bezdikian V, Driessen B, Gunther RA (2004) Measuring circulating blood volume using infused hemoglobin-based oxygen carrier (HBOC, Oxyglobin®) as an indicator: Verification in a canine hypovolemia model. Anesth Analg: submitted |
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