1999 Ph.D. in Physiology, Bogomoletz Institute of Physiology (Kiev, Ukraine)

1999-2002 Postdoctoral training (molecular neuropharmacology), University of Pennsylvania, Philadelphia, PA

American Academy of Sleep Medicine (member since 2003
International Society for Neurochemistry (member since 2004)

My primary research interests are in the molecular and cellular mechanisms of the hypothalamic control of sleep and wakefulness, their ontogenetic development, and the mechanisms by which early developmental insults, such as prenatal exposure to alcohol disrupt neurochemical signaling involved in the regulation of sleep.

My research experience also includes:

• central regulation of normal and disordered breathing;
• postnatal development of the central pathways involved in the regulation of breathing;
• molecular and cellular mechanisms of oxygen deficiency (hypoxia);
• molecular mechanisms of metabolic disorders.

In our studies, we combine in vivo and in vitro experimental approaches and use various methods of molecular and cellular biology, neuroanatomy and electrophysiology.

Marchenko, VA, LP Voitenko, DV Volgin, VB Fenik, DA Vasilenko (1996) Pacemaker properties of respiratory neurons of the ventrolateral medullary regions in early postnatal rats. Neurophysiology 28:273-284

Volgin, DV, VA Maiskii, DA Vasilenko, MM Seredenko (2000) NADPH-diaphorase-containing neurons in the medullary structures involved in generation of the respiratory activity in neonatal rats. Neurophysiology 32:99 - 105.

Volgin, D, A Volgina, M Seredenko (2000) Involvement of nitric oxide in regulation of the medullary respiratory rhythm in neonatal rats. Acta Neurobiol Exp 60:175-186.

Volgin, DV, M Mackiewicz, L Kubin (2001) a1B receptors are the main postsynaptic mediators of adrenergic excitation in brainstem motoneurons, a single-cell RT-PCR study. J Chem Neuroanat 22:157-166.

Volgin, DV, M Saghir, L Kubin (2002) Developmental changes in the orexin 2 receptor mRNA in hypoglossal motoneurons. NeuroReport 13:433-436.

Volgin, DV, R Fay, L Kubin (2003) Postnatal development of serotonin 1B, 2A and 2C receptors in brainstem motoneurons. European J Neurosci 17:1179-1188.

Wang, L, JC Whitbeck, WC Lawrence, DV Volgin, LJ Bello (2003) Expression of the genomic form of the bovine viral diarrhea virus E2 ORF in a bovine herpesvirus-1 vector. Virus Genes 27:83-91.

Volgin, DV, J. Swan, L Kubin (2004) Single-cell RT-PCR gene expression profiling of acutely dissociated and immunocytochemically identified central neurons. J Neurosci Meth 136:229-236.

Roy, A, DV Volgin, S Baby, A Mokashi, L Kubin, S Lahiri (2004) Activation of HIF-1a mRNA by hypoxia and iron chelator in isolated rat carotid body. Neurosci Lett 363:229-232.

Volgin, DV, VB Fenik, R Fay, S. Okabe, RO Davies, L Kubin (2004) Serotonergic receptors and effects in hypoglossal and laryngeal motoneurons. Semi-quantitative studies in neonatal and adult rats. In: Postgenomic Perspectives in Modeling and Control of Breathing, ed. by J Champagnat, M Denavit-Saubie, G Fortin et al. Kluwer Academic/Plenum Publishers, 2004. P. 183-188.

Volgin, DV, L Kubin (2006) Chronic intermittent hypoxia alters hypothalamic transcription of genes involved in metabolic regulation. Auton Neurosci 126-127:93-99.

Volgin DV, L Kubin (2007) Regionally selective effects of GABA on hypothalamic GABAA receptor mRNA in vitro. Biochem Biophys Res Com 353:726-732.

Thangavel, C, RN Dhir, DV Volgin, BH Shapiro (2007) Sex-dependent expression of CYP2C11 in spleen, thymus and bone marrow regulated by growth hormone. Biochem Pharmacol 74:1476-1484.

Volgin, D.V. Perinatal alcohol exposure leads to long-lasting overexpression of GABA(A) receptors in the rat posterior hypothalamus and increases behavioral sensitivity to gaboxadol. Sleep (submitted).