| Peter J. Felsburg V.M.D., Ph.D. |
| Trustee Professor of Clinical Immunology Department of Clinical Studies -Philadelphia 3900 Delancey Street School of Veterinary Medicine University of Pennsylvania Philadelphia, PA 19104-6010 |
| Qualifications |
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-VMD, University of Pennsylvania
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| Clinical Interests |
| Clinical Immunology |
| Research Interests |
| Hereditary immunodeficiencies, SCID, gene therapy |
| Selected Publications |
| Suter SE, Gouthro TA, McSweeney PA, Nash RA, Haskins ME, Felsburg PJ, Henthorn PS. (2004) Isolation and characterization of pediatric canine bone marrow CD34(+) cells. Vet Immunol Immunopathol. 101(1-2):31-47.
Cruickshank SM, McVay LD, Baumgart DC, Felsburg PJ, Carding SR. (2004) Colonic epithelial cell mediated suppression of CD4 T c Suter SE, Gouthro TA, McSweeney PA, Nash RA, Haskins ME, Felsburg PJ, Henthorn PS. (2004) Isolation and characterization of pediatric canine bone marrow CD34(+) cells. Vet Immunol Immunopathol. 101(1-2):31-47. Cruickshank SM, McVay LD, Baumgart DC, Felsburg PJ, Carding SR. (2004) Colonic epithelial cell mediated suppression of CD4 T cell activation. Gut. 53(5):678-84. Ashcroft AJ, Cruickshank SM, Croucher PI, Perry MJ, Rollinson S, Lippitt JM, Child JA, Dunstan C, Felsburg PJ, Morgan GJ, Carding SR. (2003) Colonic dendritic cells, intestinal inflammation, and T cell-mediated bone destruction are modulated by recombinant osteoprotegerin. Immunity. 19(6):849-61. Felsburg PJ, Hartnett BJ, Gouthro TA, Henthorn PS. (2003) Thymopoiesis and T cell development in common gamma chain-deficient dogs. Immunol Res. 27(2-3):235-46. Felsburg PJ. (2002) Overview of immune system development in the dog: comparison with humans. Hum Exp Toxicol. 21(9-10):487-92. Hartnett BJ, Yao D, Suter SE, Ellinwood NM, Henthorn PS, Moore PE, McSweeney PA, Nash RA, Brown JD, Weinberg KI, Felsburg PJ. (2002) Transplantation of X-linked severe combined immunodeficient dogs with CD34+ bone marrow cells. Biol Blood Marrow Transplant. 8(4):188-97. Morris DO, Clayton DJ, Drobatz KJ, Felsburg PJ. (2002) Response to Malassezia pachydermatis by peripheral blood mononuclear cells from clinically normal and atopic dogs. Am J Vet Res. 63(3):358-62. Hartnett BJ, Somberg RL, Krakowka S, Ochs HD, HogenEsch H, Moore PF, Weinberg KI, Felsburg PJ. (2000) B-cell function in canine X-linked severe combined immunodeficiency. Vet Immunol Immunopathol. 75(1-2):121-34. Hartnett BJ, Henthorn PS, Moore PF, Weinberg KI, Ochs HD, Felsburg PJ. (1999) Bone marrow transplantation for canine X-linked severe combined immunodeficiency. Vet Immunol Immunopathol. 69(2-4):137-44. Felsburg PJ, Hartnett BJ, Henthorn PS, Moore PF, Krakowka S, Ochs HD. (1999) Canine X-linked severe combined immunodeficiency. Vet Immunol Immunopathol. 69(2-4):127-35. Felsburg PJ, Somberg RL, Hartnett BJ, Henthorn PS, Carding SR. (1998) Canine X-linked severe combined immunodeficiency. A model for investigating the requirement for the common gamma chain (gamma c) in human lymphocyte development and function. Immunol Res. 17(1-2):63-73. Pullen RP, Somberg RL, Felsburg PJ, Henthorn PS. (1997) X-linked severe combined immunodeficiency in a family of Cardigan Welsh corgis. J Am Anim Hosp Assoc. 33(6):494-9. Felsburg PJ, Somberg RL, Hartnett BJ, Suter SF, Henthorn PS, Moore PF, Weinberg KI, Ochs HD. (1997) Full immunologic reconstitution following nonconditioned bone marrow transplantation for canine X-linked severe combined immunodeficiency. Blood. 90(8):3214-21. Somberg RL, Tipold A, Hartnett BJ, Moore PF, Henthorn PS, Felsburg PJ. (1996) Postnatal development of T cells in dogs with X-linked severe combined immunodeficiency. Hogenesch H, Snyder PW, Scott-Moncrieff JC, Glickman LT, Felsburg PJ. (1995) Interleukin-6 activity in dogs with juvenile polyarteritis syndrome: effect of corticosteroids. Clin Immunol Immunopathol. 77(1):107-10. Somberg RL, Pullen RP, Casal ML, Patterson DF, Felsburg PJ, Henthorn PS. (1995) A single nucleotide insertion in the canine interleukin-2 receptor gamma chain results in X-linked severe combined immunodeficiency disease. Vet Immunol Immunopathol. 47(3-4):203-13. Snyder PW, Kazacos EA, Scott-Moncrieff JC, HogenEsch H, Carlton WW, Glickman LT, Felsburg PJ. (1995) Pathologic features of naturally occurring juvenile polyarteritis in beagle dogs. Vet Pathol. 32(4):337-45. Somberg RL, Robinson JP, Felsburg PJ. (1994) T lymphocyte development and function in dogs with X-linked severe combined immunodeficiency. J Immunol. 153(9):4006-15. Henthorn PS, Somberg RL, Fimiani VM, Puck JM, Patterson DF, Felsburg PJ. (1994) IL-2R gamma gene microdeletion demonstrates that canine X-linked severe combined immunodeficiency is a homologue of the human disease. Genomics. 23(1):69-74. Deschenes SM, Puck JM, Dutra AS, Somberg RL, Felsburg PJ, Henthorn PS. (1994) Comparative mapping of canine and human proximal Xq and genetic analysis of canine X-linked severe combined immunodeficiency. Genomics. 23(1):62-8. |