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| Qualifications |
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- Director of Metabolic Genetic Laboratory
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| Bio |
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| Urs Giger received his veterinary degree from the University of Zürich, Switzerland, where he also pursued his initial clinical training in small animal medicine and surgery and completed a doctoral thesis and postgraduate training in experimental medicine and biology. In 1981, he moved as a postdoctoral fellow to the United States, where he subsequently completed a residency in small animal medicine at the University of Florida. He then joined the faculty of the School of Veterinary Medicine at the University of Pennsylvania in Philadelphia and has been a clinician in Medicine and Pediatrics/Genetics. He is now the Charlotte Newton Sheppard Professor of Medicine and Chief of the Section of Medical Genetics and has a secondary appointment at the Medical School and at the University of Zurich. He is a diplomate of the American and European College of the Veterinary Internal Medicine and is heading the Pediatrics and Genetics Clinic, the NIH-supported Genetic Metabolic Testing Laboratory, the Josephine Deubler Genetic Disease Testing Laboratory, and the Transfusion Medicine Program at the University of Pennsylvania. Dr. Giger's three major research areas, which by nature overlap, are hereditary disorders, hematologic diseases, and transfusion medicine in dogs and cats. |
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| Memberships |
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-American Veterinary Medical Association -American Animal Hospital Association -Phi Zeta - Honor Society (beta chapter) -American College of Veterinary Internal Medicine -European College of Veterinary Internal Medicine -European College of Veterinary Cllinical Pathology -John Morgan Society, University of Pennsylvania -International Society of Animal Genetics -American Society of Veterinary Clinical Pathology -American Society of Hematology -American Association of Blood Banks -Association of Veterinary Hematology & Transfusion Medicine -American Association of Feline Practitioners -European Society of Veterinary Clinical Pathology |
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| Clinical Interests |
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| Clinical Genetics, Pediatrics, Hematology, Transfusion Medicine |
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| Research Interests |
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| Hereditary disorders of companion animals in particular hematologic and metabolic defects; hematologic diseases and transfusion medicine |
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| Selected Publications |
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| Weingart C, Giger U, Kohn B. (2004) Whole blood transfusions in 91 cats: a clinical evaluation. J Feline Med Surg. 6(3):139-48.
Silverstein Dombrowski DC, Carmichael KP, Wang P, O'Malley TM, Haskins ME, Giger U. (2004) Mucopolysaccharidosis type VII in a German Shepherd Dog. J Am Vet Med Assoc. 224(4):553-7, 532-3. Griffin A, Callan MB, Shofer FS, Giger U. (2003) Evaluation of a canine D-dimer point-of-care test kit for use in samples obtained from dogs with disseminated intravascular coagulation, thromboembolic disease, and hemorrhage. Am J Vet Res. 64(12):1562-9. Aronson LR, Preston A, Bhalerao DP, Drobatz KJ, Giger U. (2003) Evaluation of erythropoiesis and changes in serum erythropoietin concentration in cats after renal transplantation. Am J Vet Res. 64(10):1248-54. Kohn B, Weingart C, Giger U. (2003) Haemorrhage in seven cats with suspected anticoagulant rodenticide intoxication. J Feline Med Surg. 5(5):295-304. Mazrier H, Van Hoeven M, Wang P, Knox VW, Aguirre GD, Holt E, Wiemelt SP, Sleeper MM, Hubler M, Haskins ME, Giger U. (2003) Inheritance, biochemical abnormalities, and clinical features of feline mucolipidosis II: the first animal model of human I-cell disease. J Hered. 94(5):363-73. Arikan S, Duru SY, Gurkan M, Agaoglu ZT, Giger U. (2003) Blood type A and B frequencies in Turkish Van and Angora cats in Turkey. J Vet Med A Physiol Pathol Clin Med. 50(6):303-6. Mason N, Duval D, Shofer FS, Giger U. (2003) Cyclophosphamide exerts no beneficial effect over prednisone alone in the initial treatment of acute immune-mediated hemolytic anemia in dogs: a randomized controlled clinical trial. J Vet Intern Med. 17(2):206-12. Ellinwood NM, Wang P, Skeen T, Sharp NJ, Cesta M, Decker S, Edwards NJ, Bublot I, Thompson JN, Bush W, Hardam E, Haskins ME, Giger U. (2003) A model of mucopolysaccharidosis IIIB (Sanfilippo syndrome type IIIB): N-acetyl-alpha-D-glucosaminidase deficiency in Schipperke dogs. J Inherit Metab Dis. 26(5):489-504. Callan MB, Giger U. (2002) Effect of desmopressin acetate administration on primary hemostasis in Doberman Pinschers with type-1 von Willebrand disease as assessed by a point-of-care instrument. Am J Vet Res. 63(12):1700-6. Bhalerao DP, Rajpurohit Y, Vite CH, Giger U. (2002) Detection of a genetic mutation for myotonia congenita among Miniature Schnauzers and identification of a common carrier ancestor. Foureman P, Whiteley M, Giger U. (2002) Canine leukocyte adhesion deficiency: presence of the Cys36Ser beta-2 integrin mutation in an affected US Irish Setter cross-breed dog and in US Irish Red and White Setters. J Vet Intern Med. 16(5):518-23. Gibson GR, Callan MB, Hoffman V, Giger U. (2002) Use of a hemoglobin-based oxygen-carrying solution in cats: 72 cases (1998-2000). J Am Vet Med Assoc. 221(1):96-102. Giger U, Oakley DA, Owens SD, Schantz P. (2002) Leishmania donovani transmission by packed RBC transfusion to anemic dogs in the United States. Transfusion. 42(3):381-3. No abstract available. Valentine BA, Bildfell RJ, Cooper BJ, Giger U, Fischer KA. (2002) Complex polysaccharide inclusions in skeletal muscle adjacent to sarcomas in two dogs. Vet Pathol. 39(2):278-80. Rozanski EA, Callan MB, Hughes D, Sanders N, Giger U. (2002) Comparison of platelet count recovery with use of vincristine and prednisone or prednisone alone for treatment for severe immune-mediated thrombocytopenia in dogs. J Am Vet Med Assoc. 220(4):477-81. Byrne KP, Giger U. (2002) Use of human immunoglobulin for treatment of severe erythema multiforme in a cat. J Am Vet Med Assoc. 220(2):197-201, 183-4. Haskins M, Casal M, Ellinwood NM, Melniczek J, Mazrier H, Giger U. (2002) Animal models for mucopolysaccharidoses and their clinical relevance. Acta Paediatr Suppl. 91(439):88-97. Owens SD, Oakley DA, Marryott K, Hatchett W, Walton R, Nolan TJ, Newton A, Steurer F, Schantz P, Giger U. (2001) Transmission of visceral leishmaniasis through blood transfusions from infected English foxhounds to anemic dogs. J Am Vet Med Assoc. 219(8):1076-83. Tseng LW, Hughes D, Giger U. (2001) Evaluation of a point-of-care coagulation analyzer for measurement of prothrombin time, activated partial thromboplastin time, and activated clotting time in dogs. Am J Vet Res. 62(9):1455-60. Aronovich EL, Johnston JM, Wang P, Giger U, Whitley CB. (2001) Molecular basis of mucopolysaccharidosis type IIIB in emu (Dromaius novaehollandiae): an avian model of Sanfilippo syndrome type B. Genomics. 74(3):299-305. |
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