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  Faculty
Paula Henthorn Ph.D.
Professor of Medical Genetics

Department of Clinical Studies -Philadelphia
3900 Delancey Street
School of Veterinary Medicine
University of Pennsylvania
Philadelphia, PA   19104-6010
Qualifications

-Ph.D. - Genetics, University of Wisconsin

Clinical Interests
-Control of genetic disease
Research Interests
-Genetic diseases of dogs and cats
Selected Publications

Suter SE, Gouthro TA, McSweeney PA, Nash RA, Haskins ME, Felsburg PJ, Henthorn PS. (2004) Isolation and characterization of pediatric canine bone marrow CD34(+) cells. Vet Immunol Immunopathol. 101(1-2):31-47.

Casal ML, Dambach DM, Meister T, Jezyk PF, Patterson DF, Henthorn PS. (2004) Familial glomerulonephropathy in the bullmastiff. Vet Pathol. 41(4):319-25.


Werner P, Raducha MG, Shin D, Ostrander EA, Kirkness E, Patterson DF, Henthorn PS. (2004) Assignment of 10 canine genes to the canine linkage and comparative maps. Anim Genet. 35(3):249-51.

He Q, Fyfe JC, Schaffer AA, Kilkenney A, Werner P, Kirkness EF, Henthorn PS. (2003) Canine Imerslund-Grasbeck syndrome maps to a region orthologous to HSA14q. Mamm Genome. 14(11):758-64.

Felsburg PJ, Hartnett BJ, Gouthro TA, Henthorn PS. (2003) Thymopoiesis and T cell development in common gamma chain-deficient dogs. Immunol Res. 27(2-3):235-46. Review.

Palmer LE, O'Shaughnessy AL, Preston RR, Santos L, Balija VS, Nascimento LU, Zutavern TL, Henthorn PS, Hannon GJ, McCombie WR. (2003) A survey of canine expressed sequence tags and a display of their annotations through a flexible web-based interface. J Hered. 94(1):15-22.

Kimmel SE, Ward CR, Henthorn PS, Hess RS. (2002) Familial insulin-dependent diabetes mellitus in Samoyed dogs. J Am Anim Hosp Assoc. 38(3):235-8.

Hartnett BJ, Yao D, Suter SE, Ellinwood NM, Henthorn PS, Moore PE, McSweeney PA, Nash RA, Brown JD, Weinberg KI, Felsburg PJ. (2002) Transplantation of X-linked severe combined immunodeficient dogs with CD34+ bone marrow cells. Biol Blood Marrow Transplant. 8(4):188-97.

Mumm S, Jones J, Finnegan P, Henthorn PS, Podgornik MN, Whyte MP. (2002) Denaturing gradient gel electrophoresis analysis of the tissue nonspecific alkaline phosphatase isoenzyme gene in hypophosphatasia. Mol Genet Metab. 75(2):143-53.

Sleeper MM, Henthorn PS, Vijayasarathy C, Dambach DM, Bowers T, Tijskens P, Armstrong CF, Lankford EB. (2002) Dilated cardiomyopathy in juvenile Portuguese Water Dogs. J Vet Intern Med. 16(1):52-62.

Sleeper MM, Henthorn PS, Lankford EB. (2001) Differing opinion regarding the etiology of juvenile cardiomyopathy in Portuguese water dogs. Am J Med Genet. 104(3):262-4.

Henthorn PS, Liu J, Gidalevich T, Fang J, Casal ML, Patterson DF, Giger U. (2000) Canine cystinuria: polymorphism in the canine SLC3A1 gene and identification of a nonsense mutation in cystinuric Newfoundland dogs. Hum Genet. 107(4):295-303.

Melniczek JR, Dambach D, Prociuk U, Jezyk PF, Henthorn PS, Patterson DF, Giger U. (1999) Sry-negative XX sex reversal in a family of Norwegian Elkhounds. J Vet Intern Med. 13(6):564-9.

Moore CA, Curry CJ, Henthorn PS, Smith JA, Smith JC, O'Lague P, Coburn SP, Weaver DD, Whyte MP. (1999) Mild autosomal dominant hypophosphatasia: in utero presentation in two families. Am J Med Genet. 86(5):410-5.

Hartnett BJ, Henthorn PS, Moore PF, Weinberg KI, Ochs HD, Felsburg PJ. (1999) Bone marrow transplantation for canine X-linked severe combined immunodeficiency. Vet Immunol Immunopathol. 69(2-4):137-44.

Felsburg PJ, Hartnett BJ, Henthorn PS, Moore PF, Krakowka S, Ochs HD. (1999) Canine X-linked severe combined immunodeficiency. Vet Immunol Immunopathol. 69(2-4):127-35.

Werner P, Raducha MG, Prociuk U, Budarf M, Henthorn PS, Patterson DF. (1999) Comparative mapping of the DiGeorge region in the dog and exclusion of linkage to inherited canine conotruncal heart defects. J Hered. 90(4):494-8.

Werner P, Mellersh CS, Raducha MG, DeRose S, Acland GM, Prociuk U, Wiegand N, Aguirre GD, Henthorn PS, Patterson DF, Ostrander EA. (1999) Anchoring of canine linkage groups with chromosome-specific markers. Mamm Genome. 10(8):814-23.

Whitwam T, Haskins ME, Henthorn PS, Bodine DM, Puck JM. (1999) Canine lymphocyte expression of retrovirally transferred human common gamma chain. Ann N Y Acad Sci. 872:387-90.

Fyfe JC, Kurzhals RL, Lassaline ME, Henthorn PS, Alur PR, Wang P, Wolfe JH, Giger U, Haskins ME, Patterson DF, Sun H, Jain S, Yuhki N. (1999) Molecular basis of feline beta-glucuronidase deficiency: an animal model of mucopolysaccharidosis VII. Genomics. 58(2):121-8.