Antibiotic use in veterinary medicine: Antimicrobial are used extensively in animals, and their use can contribute to the development of antimicrobial resistance. Dr. Redding is interested in better understanding how antibiotics are used in veterinary settings, discerning the clinical and One Health implications of their use and developing ways to refine their use.
The animal reservoir of Clostridium difficile: Clostridium difficile is the leading cause of antibiotic-associated and nosocomial diarrhea in humans and a significant enteric pathogen in many species of animals. It is generally accepted that the administration of antibiotics is the primary risk factor for the development and recurrence of C. difficile infection. However, patients can develop infections with C. difficile outside of a healthcare facility without the prior use of antibiotics. Dr. Redding is interested in studying whether animals - particularly companion animals - can serve as a reservoir for C. difficile infections in people.
Redding L E, Cubas-Delgado F, Sammel M D, Smith G, Galligan D T, Levy M Z, Hennessy S Comparison of two methods for collecting antibiotic use data on small dairy farms. Preventive veterinary medicine 114: 213-22, 2014.Redding L E, Cubas-Delgado F, Sammel M D, Smith G, Galligan D T, Levy M Z, Hennessy S The use of antibiotics on small dairy farms in rural Peru. Preventive veterinary medicine 113: 88-95, 2014.Redding L E, Cubas-Delgado F, Sammel M D, Smith G, Galligan D T, Levy M Z, Hennessy S Antibiotic residues in milk from small dairy farms in rural Peru. Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 31: 1001-8, 2014.Redding L E, Barg F K, Smith G, Galligan D T, Levy M Z, Hennessy S The role of veterinarians and feed-store vendors in the prescription and use of antibiotics on small dairy farms in rural Peru. Journal of dairy science 96: 7349-54, 2013.Redding Laurel, Chetri Dipesh Kumar, Lamichhane Dirga Kumar, Chay Yoon, Aldinger Lauren, Ferguson James Animal production systems of small farms in the Kaski district of Nepal. Tropical animal health and production 44: 1605-13, 2012.Redding Laurel, Weiner David B DNA vaccines in veterinary use. Expert review of vaccines 8: 1251-76, 2009.Redding Laurel E, Sohn Michael D, McKone Thomas E, Chen Jein-Wen, Wang Shu-Li, Hsieh Dennis P H, Yang Raymond S H Population physiologically based pharmacokinetic modeling for the human lactational transfer of PCB-153 with consideration of worldwide human biomonitoring results. Environmental health perspectives 116: 1629-35, 2008.Lin Pinpin, Chen Jein-Wen, Chang Louis W, Wu Jui-Pin, Redding Laurel, Chang Han, Yeh Teng-Kuang, Yang Chung Shi, Tsai Ming-Hsien, Wang Hsiu-Jen, Kuo Yu-Chun, Yang Raymond S H Computational and ultrastructural toxicology of a nanoparticle, Quantum Dot 705, in mice. Environmental science & technology 42: 6264-70, 2008.
VMD (Veterinary Medicine) University of Pennsylvania School of Veterninary Medicine, 2015PhD (Epidemiology (pharmacoepidemiology)) University of Pennsylvania Perelman School of Medicine, 2015BA (Religion) Duke University, 2006