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SYDNEY M. EVANS, BS, VMD, MS
Vice Chair, Faculty Affairs, University of Pennsylvania, School of Medicine, Department of Radiation Oncology

Education Officer, University of Pennsylvania School of Medicine Department of Radiation Oncology

American College of Veterinary Radiology


Contact Information:
187 John Morgan Building 3620 Hamilton Walk
 Phone 215-898-0074
 Email sydevans@mail.med.upenn.edu

Measuring hypoxia and predicting treatment response in brain tumors
Measuring hypoxia and predicting treatment responsein cervix cancer
Measuring hypoxia and predicting treatment responsein head and neck squamous cell carcinoma
Measuring hypoxia and predicting treatment responsein carcinomatosis and sarcomatosis
Measuring hypoxia and predicting treatment responsein pleural cancers
Measuring hypoxia and predicting treatment response in soft tissue sarcomas

Measuring hypoxia in vivo
Animal Models of human disease
Cancer physiology, proliferation
Cancer physiology, tumor vasculature

Sood, N Jenkins, WT Yang, X-Y Shah, NN Katz, JS Koch, CJ Frail, PR Therein, MJ Hammer, DA Evans, SM Biodegradable polymersomes for the delivery of Gemcitabine to Panc-1 cells Journal of Pharmaceutics (on line) 2013: , 2013.

Koch CJ, Jenkins WT, Jenkins KW, Yang XY, Shuman AL, Pickup S, Riehl1 CR, Paudya R, Poptani H, Evans SM Mechanisms of Blood Flow and Hypoxia Production in Rat 9L Epigastric Tumors Tumor Microenvironment and Therapy 1: 1-13, 2012.

Lilie L Lin, LL Antti Silvoniemi James B Stubbs Ramesh Rengan Sami Suilamo Olof Solin Chaitanya Divgi Olli Eskola Jonathan M. Sorger Michael G. Stabin Alexander Kachur Stephen M. Hahn Tove Grönroos Sarita Forsback Sydney M Evans Cameron J. Koch Heikki Minn Radiation Dosimetry and Biodistribution of the Hypoxia Tracer 18F-EF5 in Oncologic Patients. Cancer Biotherapy & Radiopharmaceuticals 27: 412-9, 2012.

Marotta D, Karar J, Jenkins WT, Kumanova M, Tobias JW, Baldwin D, Hadjigeorgiou A, Alexiou P, Evans SM, Alarcon R, Maity A, Koch CJ, Koumenis C In vivo profiling of hypoxic gene expression in gliomas using the hypoxia marker EF5 and laser-capture microdissection. Cancer Research 71: 779-89, 2011 .

Evans SM, Jenkins KW, Chen HI, Jenkins WT, Judy KD, Hwang W-T, Lustig RA, Judkins AR, Grady MS, Hahn SM, Koch CJ The Relationship among Hypoxia, Proliferation, and Outcome in Patients with De Novo Glioblastoma: A Pilot Study. Translational Oncology 3: 160–9, 2010 .

Koch CJ, Scheuermann JS, Divgi C, Judy KD, Kachur A, Freifelder R, Saffer J, Karp J, Stubbs JM, Hahn SM, Driesbaugh J, Smith D, Prendergast S, Evans SM Biodistribution and dosimetry of 18F-EF5 in cancer patients with preliminary comparison of 18F-EF5 uptake versus EF5 binding in human glioblastoma. European Journal of Nuclear medicine and Molecular Imaging 37: 2048-59, 2010.

Koch CJ, Shuman AL, Jenkins WT, Kachur AV, Karp JS, Freifelder R, Dolbier WR, Evans SM The radiation response of cells from 9L gliosarcoma tumors is correlated with [F18]-EF5 uptake. International Journal of Radiation Biology 85: 1137-47, 2009 .

Cerniglia G, Pore N, Tsai JH, Schultz S, Mick R, Regine C, Xiaoman X, Durduran T, Yodh AG, Evans SM, Koch CJ, Hahn SM, Quon H, Sehgal CM, Lee W M-F, Maity A Epidermal growth factor inhibition modulates the microenvironment by vascular normalization to improve chemotherapy and radiotherapy efficacy. PloS one 4: e6539, 2009.

Komar G, Seppänen M, Eskola O, Lindholm Paula, Grönroos T, Forsback S, Sipilä H, Evans SM, Solin O, Minn H 18F-EF5: A new PET tracer for imaging hypoxia in head and neck cancer. Journal of Nuclear Medicine 49: 1944-51, 2008.

Evans, SM, Jenkins KW, Jenkins WT, Dilling T, Judy KD, Schrlau A, Judkins A, Hahn SM, Koch CJ Imaging and analytical methods as applied to the evaluation of vasculature and hypoxia in human brain tumors. Radiation Research 170: 677-90, 2008.

BS (Pre-Veterinary Medicine) Rutgers University, Douglas College, 1973

VMD (Veterinary Medicine) University of Pennsylvania, School of Veterinary Medicine , 1977

MS (Comparative Medical Sciences) University of Pennsylvania, School of Veterinary Medicine , 1986