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URS GIGER, DVM, PD, MS
Charlotte Newton Sheppard Chair of Medicine , University of Pennsylvania

Director, Josephine Deubler Genetic Disease Testing Laboratory, University of Pennsylvania, Department of Clinical Studies, Philadelphia School of Veterinary Medicine, University of Pennsylvania

Head of Clinical Program in Medical Genetics and Pediatrics, Department of Clinical Studies, Philadelphia School of Veterinary Medicine, University of Pennsylvania

Director of Metabolic Genetics Screening Laboratory , Department of Clinical Studies, Philadelphia School of Veterinary Medicine, University of Pennsylvania 1988-present

Secondary Appointment as (Assistant/Associate/Full) Professor of Medicine, Department of Clinical Studies, Philadelphia School of Veterinary Medicine, University of Pennsylvania

Diplomate of the European College of Veterinary Clinical Pathology

Diplomate of the European College of Veterinary Internal Medicine - Companion Animals

Diplomate of the American College of Veterinary Internal Medicine, Specialty of Small Animal Internal Medicine

FVH Spezialtierarzt für Kleintiere, Switzerland

Clinical Specialties: Genetics,
Research Areas: Genetics, Transfusion Medicine, Animal models of human diseases, Hematology,

Contact Information:
Section of Medical Genetics
University of Pennsylvania
School of Veterinary Medicine
3900 Delancey Street
 Phone 215-898-8830
 Fax 215-573-2162
 Email giger@vet.upenn.edu

Clinical Genetics, Hematology, and Transfusion Medicine in Companion Animals

Clinical Genetics, Hematology, Transfusion Medicine, Animal Models of Human Disease

Inal Gultekin G, Raj K, Lehman S, Hillström A, Giger U. Missense mutation in PFKM associated with muscle-type phosphofructokinase deficiency in the Wachtelhund dog. Molecular Cell Probes : epub, 2012.

Seth M, Jackson K,V, Winzelberg S, Giger U Comparison of gel column, card and cartridge techniques for Dog Erythrocyte Antigen Am J Vet Res 73: 213–219, 2012.

Inal Gultekin G, Raj K, Foureman P, Lehman S, Manhart K, Abdulmalik O, Giger U. Erythrocytic pyruvate kinase mutations causing hemolytic anemia, osteosclerosis, and secondary hemochromatosis in dogs. J Vet Intern Med 26: 935–944, 2012.

Jolly RD, Hopwood JJ, Marshall NR, Jenkins KS, Thompson DJ, Dittmer KE, Thompson JC, Fedele AO, Raj K, Giger U. Mucopolysaccharidosis type VI in a Miniature Poodle-type dog caused by a deletion in the arylsulphatase B gene. NZ Vet J 60: 183-188, 2012.

Seth M, Jackson KV, Giger U Comparison of 5 blood typing methods for the feline AB blood group system. Am J Vet Res 72: 203-9, 2011.

Patterson J, Rousseau A, Kessler RJ, Giger U In vitro lysis and acute transfusion reactions with hemolysis caused by inappropriate storage of canine red blood cell products J Vet Intern Med 25: 927-933, 2011.

Clavero S, Bishop DF, Giger U, Haskins ME, Desnick RJ Feline congenital erythropoietic porphyria: Two homozygous UROS missense mutations cause the enzyme deficiency and porphyrin accumulation. Mol Med 16: 381-8, 2010.

Clavero S, Bishop DF, Haskins ME, Giger U, Kauppinen R, Desnick RJ Feline acute intermittent porphyria: a phenocopy masquerading as an erythropoietic porphyria due to dominant and recessive hydroxymethylbilane synthase mutations. Hum Mol Genet 19: 584-96, 2010.

Margaritis P, Roy E, Aljamali MN, Downey HD, Giger U, Zhou S, Merricks E, Dillow A, Ezban M, Nichols TC, High KA. Successful treatment of canine hemophilia by continuous expression of canine FVIIa. Blood 113: 3682-9, 2009.

Pontius JU, Mullikin JC, Smith DR; Agencourt Sequencing Team, Lindblad-Toh K, Gnerre S, Clamp M, Chang J, Stephens R, Neelam B, Volfovsky N, Schäffer AA, Agarwala R, Narfström K, Murphy WJ, Giger U, Roca AL, Antunes A, Menotti-Raymond M, Yuhki N, Pecon-Slattery J, Johnson WE, Bourque G, Tesler G; NISC Comparative Sequencing Program, O'Brien SJ Initial sequence and comparative analysis of the cat genome Genome Res. 17: 1675-89, 2007.

DVM (Veterinary Medicine) Veterinär-Medizinische Fakultät, University of Zürich, 1977

PD (Internal Medicine) University of Zürich, Switzerland, 1989

MS (Comparative Sciences) University of Pennsylvania, Philadelphia, 1990