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WILFRIED MAI, Dr Méd Vét, MSc, PhD
Associate Professor of Radiology/Clinician Educator, University of Pennsylvania School of Veterinary Medicine

Chief, Section of Radiology, Department of Clinical Studies, University of Pennsylvania School of Veterinary Medicine

Diplomate of the American College of Veterinary Radiology

Diplomate of the European College of Veterinary Diagnostic Imaging

Clinical Specialties: CT-MRI
Research Areas: Diagnostic imaging, Radiology, Ultrasonography, Vascular Imaging,

Contact Information:
School of Veterinary Medicine
Section of Radiology
University of Pennsylvania
Rosenthal Imaging And Treatment Center (Room 1218)
3900 Delancey Street
215-898-3304 (phone)
215-573-6263 (fax)
wmai@vet.upenn.edu
 Phone (1) 215 898 3304
 Fax (1) 215 573 6263
 Email wmai@vet.upenn.edu

Canine and Feline Diagnostic Imaging, with focus on computed tomography and magnetic resonance imaging.

1. Clinical Research involving small animal diagnostic imaging - Evidence-based imaging
2. Vascular imaging: Computed Tomographic Angiography and Magnetic Resonance Angiography, as it applies to the diagnosis of vascular anatomical abnormalities and also functional (perfusion) evaluation of spontaneous lesions, especially neoplastic.
3. Laboratory rodent high resolution diagnostic imaging / non invasive phenotyping using diagnostic imaging. Dr Mai has completed a PhD in biomedical engineering, during which he studied the implementation and role of high-resolution diagnostic imaging to image in vivo laboratory rodents. Techniques involved were high-resolution digital radiography, high-resolution ultrasound, high field MRI and high resolution CT. Dr Mai completed part of his PhD at the Center for In Vivo Microscopy (Durham, NC), a leader in the field of high resolution MRI.

Reetz J.A., Cáceres A., Suran J.N., Oura T., Zwingenberger A., Mai W. Sensitivity, positive predictive value and interobserver variability of computed tomography in the diagnosis of bullae and blebs in dogs with spontaneous pneumothorax: 19 cases (2003-2012). Journal of the American Veterinary Medical Association 243: 244-251, 2013.

Mai W., Suran J., Caceres A.V., Reetz J. Comparison between bolus tracking and timing-bolus techniques for renal CT angiography in normal cats. Veterinary Radiology and Ultrasound 54: 343-350, 2013.

Guillem Gallach R., Mai W. Cardiac MRI findings in a dog with a diffuse pericardial mesothelioma and pericardial effusion. Journal of the American Animal Hospital Association 49: 398-402, 2013.

Schlicksup M.D., Holt D.E., Mai W., Holmes E.S., Agnello K.A. The effect of abaxial retraction on pelvic geometry following pelvic symphysiotomy. Veterinary Surgery 42: 958-962, 2013.

Paek M., Engiles J.B., Mai W. Prevalence, association with other stifle conditions, and histopathologic characteristics of tibial tuberosity radiolucencies in dogs. Veterinary Radiology and Ultrasound 54: 453-458, 2013.

Amory J., Reetz J.A., Sanchez M.D., Bradley C.W., Lewis J.R., Reiter A.M., Mai W. Computed tomographic imaging characteristics of odontogenic neoplasms in dogs. Veterinary Radiology and Ultrasound 55: 147-158, 2014.

Mendoza P., d’Anjou M.A., Carmel E.N., Fournier E., Mai W, Alexander K., Winter M., Zwingenberger A., Thrall D., Théoret C. Simulating radiographs using Computed Tomography for the purpose of teaching radiographic anatomy in veterinary medicine. Veterinary Radiology and Ultrasound 55: 251-261, 2014.

Ryan C.T., Glass E.N., Seiler G., Zwingenberger A.L., Mai W. Magnetic resonance imaging findings associated with lateral cerebral ventriculomegaly in English Bulldogs. Veterinary Radiology and Ultrasound 55: 292-299, 2014.

Lamb C.R., Mai W. Acceptance rate and reasons for rejection of manuscripts submitted to Veterinary Radiology and Ultrasound during 2012. Veterinary Radiology and Ultrasound : , 2014.

Eshar D., Briscoe J.A., Mai W. Radiographic kidney measurements in North American pet ferrets (Mustela furo) Journal of Small Animal Practice 54: 15-19, 2013.

Seiler G., Robertson I., Mai W., Widmer W., Suran J., Nemanic S., Lamb C., Lang J., Johnson J., Thrall D. Usefulness of a Half-Fourier acquisition Single-Shot Turbo Spin-Echo pulse sequence in identifying arachnoid diverticula in dogs. Veterinary Radiology and Ultrasound 53: 157-161, 2012.

Kuczynski L.A., Schwartz P., Peddle G., Huang S., Mai W., Giger U. Goiter with Vascular Anomalies in a Litter of Polish Lowland Sheepdogs. J Am Anim Hosp Assoc. 48: 278-283, 2012.

Kurosaka S., Leu N.A., Pavlov I., Han X., Bretanha-Ribeiro P.A., Xu T., Bunte R., Saha S., Mai W., Yates J.R., Rassier D.E., Kashina A. Arginylation in cardiomyocytes regulates myofibril properties to maintain heart function and prevent dilated cardiomyopathy. J Mol Cell Cardiol. 53: 333-341, 2012.

Mai W., Weisse C., Sleeper M.M. Cardiac MRI in normal dogs and two dogs with heart base tumors. Veterinary Radiology and Ultrasound 51: 428-435, 2011.

Mai W, Sutherland-Smith J. Academic radiology careers: what is academia all about? Veterinary Radiology and Ultrasound 51: 239-45, 2010.

Suran J., Durham A., Mai W., Seiler G. Contrast enhancement of extradural compressive material on magnetic resonance imaging Veterinary Radiology and Ultrasound 52: 10-16, 2011.

Cervera V., Mai W., Vite C.H., Johnson V., Dayrell-Hart B., Seiler G.S. Comparative magnetic resonance imaging findings between gliomas and presumed cerebrovascular accidents in dogs. Veterinary Radiology and Ultrasound 52: 33-40, 2011.

Mai W., Weisse C. Contrast-enhanced portal MRA in dogs with suspected congenital portal vascular anomalies. Veterinary Radiology and Ultrasound 52: 284-288, 2011.

Guillem Gallach R., Suran J., Cáceres A.V., Reetz J.A., Brown D.C., Mai W. Reliability of T2-weighted sagittal MR images for determining the location of compressive disc herniation in dogs. Veterinary Radiology and Ultrasound 52: 479-486, 2011.

Cavrenne R, Mai W Time-resolved renal contrast-enhanced MRA in normal dogs Veterinary Radiology and Ultrasound 50: 58-64, 2009.

Mai W Multi-phase time-resolved contrast-enhanced portal MRA in normal dogs Veterinary Radiology and Ultrasound 50: 52-57, 2009.

Mai W Pseudo-layering artifact on post-contrast magnetic resonance images of the bladders of 18 dogs and three cats. The Veterinary Record 163: 116-119, 2008.

Ivancic M., Mai W. Qualitative and quantitative comparison of renal vs. hepatic ultrasonographic intensity in healthy dogs. Veterinary Radiology and Ultrasound 49: 368-373, 2008.

Mai W., Caceres A.V. Dual-phase computed tomographic angiography in three dogs with pancreatic insulinoma Veterinary Radiology and Ultrasound 49: 141-148, 2008.

Cáceres A.V., Zwingenberger A.L., Aronson L.R., Mai W Characterization of normal feline renal vascular anatomy with dual-phase CT angiography Veterinary Radiology and Ultrasound 49: 350-356, 2008.

Valdés-Martínez A., Seiler G., Mai W., Bolt D.M., Mudge M., Dukti S.A., Hubert J.D. Quantitative analysis of scintigraphic findings in tibial stress fractures in Thoroughbred racehorses American Journal of Veterinary Research 69: 886-890, 2008.

Valdés-Martínez A., Cianciolo R., Mai W. Association between renal hypoechoic subcapsular thickening and lymphosarcoma in cats Veterinary Radiology and Ultrasound 48: 357-360, 2007.

Chuzel T., Couturier L., Nicolier A., Bublot I., Mai W., Cadore J.L. Persistent truncus arteriosus in a cat Journal of Veterinary Cardiology 9: 43-46, 2007.

Kinns J., Mai W. Association between malignancy and sonographic heterogeneity in canine and feline abdominal lymph nodes Veterinary Radiology and Ultrasound 48: 565-569, 2007.

Spriet M., Mai W., McKnight A. Asymmetric signal intensity in normal collateral ligaments of the distal interphalangeal joint in horses with a low-field MRI system due to the magic angle effect Veterinary Radiology & Ultrasound 48: 95-100, 2007.

Kinns J., Mai W., Seiler G., Zwingenberger A., Johnson V., Caceres A., Valdes-Martinez A., Schwarz T. Radiographic sensitivity and negative predictive value for acute canine spinal trauma Veterinary Radiology & Ultrasound 47: 563-70, 2006.

Wiart M., Carme S., Mai W., Larsson HB., Neyran B., Canet-Soulas E. In vivo quantification of regional myocardial blood flow: validity of the fast-exchange approximation for intravascular T1 contrast agent and long inversion time Magnetic Resonance in Medicine 56: 340-7, 2006.

Mai W. The hilar perivenous hyperechoic triangle as a sign of acute splenic torsion in dogs Veterinary Radiology & Ultrasound 47: 487-91, 2006.

Reetz JA., Mai W., Muravnick KB., Goldschmidt MH., Schwarz T. Computed tomographic evaluation of anatomic and pathologic variations in the feline nasal septum and paranasal sinuses Veterinary Radiology & Ultrasound 47: 321-7, 2006.

Carme S., Mai W., Mazzadi A., Janier M., Revel D., Magnin I., Wiart M., Neyran B., Canet-Soulas E. Importance of parametric mapping and deconvolution in analyzing magnetic resonance myocardial perfusion images Investigative Radiology 41: 374-83, 2006.

Mai W., Badea CT., Wheeler CT., Hedlund LW., Johnson GA. Effects of breathing and cardiac motion on spatial resolution in the microscopic imaging of rodents Magnetic Resonance in Medicine 53: 858-65, 2005.

Chuzel T., Bublot I., Mai W. What is your diagnosis? Primary hyperparathyroidism in a dog Journal of the American Veterinary Medical Association 226: 203-4, 2005.

Brown S.D.M., Chambon P., Hrabe de Angelis M. & The EUMORPHIA Consortium EMPReSS: standardized phenotype screens for functional annotation of the mouse genome Nature Genetics 37: 1155, 2005.

Mai W., Le Floc'h J., Vray D., Samarut J., Barthez P., Janier M. Evaluation of cardiovascular flow characteristics in the 129Sv mouse fetus using color-Doppler-guided spectral Doppler ultrasound Veterinary Radiology & Ultrasound 45: 568-73, 2004.

Mai W., Barraud L., Lefrancois L., Scoazec JY., Guerret S., Vray D., Merle P., Vitvitski-Trepo L., Trepo C., Janier MF. Ultrasound detection of spontaneous hepato-cellular carcinomas in X/myc bitransgenic mice Liver International 24: 651-7, 2004.

Mai W., Janier MF., Allioli N., Quignodon L., Chuzel T., Flamant F., Samarut J. Thyroid hormone receptor alpha is a molecular switch of cardiac function between fetal and postnatal life Proceedings of the National Academy of Sciences of the United States of America 101: 10332-7, 2004.

Chuzel TA., Mai W., Ponce FM. What is your diagnosis? Abdominal distension with loss of intra-abdominal contrast and decreased visibility of serosal surfaces of the small and large intestines Journal of the American Veterinary Medical Association 224: 1921-2, 2004.

Sappey-Marinier D., Beuf O., Billotey C., Chereul E., Dupuy J., Jeandey M., Grenier D., Hasserodt J., Langlois J.B., Lartizien C., Mai W., Odet C., Samarut J., Vray D., Zimmer L., Janier M. The ANIMAGE project: a multimodal imaging platform for small animal research. Nucl Instr Meth Phys Res A. 527: 117-123, 2004.

Mai W Chapter 7 – The Heart and Major Vessels (Contribution: Congenital Cardiac Diseases) BSAVA Manual of Canine and Feline Thoracic Imaging : 110-134, 2008.

Mai W Chapter 12 – The Lung Parenchyma (Contribution: Normal Radiographic Aspect of the Lungs) BSAVA Manual of Canine and Feline Thoracic Imaging : 242-248, 2008.

Mai W. Chapter 9 - The Stomach (Contribution: Gastric Radiology) BSAVA Manual of Canine and Feline Abdominal Radiography : 87-109, 2009.

Mai W., Ledieu D., Venturini L., Fournel C., Fau D., Palazzi X., Magnol JP. Ultrasonographic appearance of intra-abdominal granuloma secondary to retained surgical sponge Veterinary Radiology & Ultrasound 42: 157-60, 2001.

Pouchelon JL., Chetboul V., Devauchelle P., Delisle F., Mai W., Vial V. Diagnosis of pulmonary thromboembolism in a cat using echocardiography and pulmonary scintigraphy Journal of Small Animal Practice 38: 306-10, 1997.

Mai W. Chapter 12 - Magnetic resonance imaging and computed tomography features of canine and feline spinal cord disease. Textbook of Veterinary Diagnostic Radiology, 6th edition, 847 pp. : 194-221, 2013.

Dr Méd Vét (Veterinary Medicine) Ecole Vétérinaire de Maisons-Alfort, France, 1998

MSc (Biomedical engineering) University Joseph Fourier, Grenoble, France, 2000

PhD (Biomedical engineering, Core Medical Imaging) University Claude Bernard (France) and Duke University (Durham, NC, USA), 2004