Links and Publications

Links & Publications

Below is a list of resource links and selected publications for Oliver Garden and other members of the Immune Regulation Laboratory.

If you are interested in a complete list of publications from Oliver and the Immune Regulation Laboratory, please see our PubMed page. For a complete list of publications from Dr. Jie Luo, please see his PubMed Bibliography.  


Selected Publications

LUO J (2018) Acetylcholine receptor-specific immunosuppressive therapy of experimental autoimmune myasthenia gravis and myasthenia gravis. Annals of the New York Academy of Sciences. doi: 10.1111/nyas.13550. PMID: 29377167

COMAZZI S, AVERY PR, GARDEN OA, RIONDATO F, RÜTGEN B and VERNAU W (2017) European canine lymphoma network consensus recommendations for reporting flow cytometry in canine hematopoietic neoplasms. Cytometry B Clinical Cytometry 92 (5): 411-419. doi: 10.1002/cyto.b.21382. PMID: 27170500

HEAPS LA, SCUDDER CJ, LIPSCOMB VJ, STEINBACH SMI, PRIESTNALL SL, MARTINEAU H, SZLADOVITS B, FOWKES RC and GARDEN OA (2017) Serum anti-Müllerian hormone concentrations before and after treatment of an ovarian granulosa cell tumour in a cat. Journal of Feline Medicine and Surgery Open Reports 3 (2): 2055116917722701. doi: 10.1177/2055116917722701. PMID: 28839946

GIBBONS N, GOULART MR, CHANG Y, EFSTATHIOU K, PURCELL R, WU Y, PETERS LM, TURMAINE M, SZLADOVITS B and GARDEN OA (2017) Phenotypic heterogeneity of peripheral monocytes in healthy dogs. Veterinary Immunology and Immunopathology 190: 26-30. doi: 10.1016/j.vetimm.2017.06.007. PMID: 28778319

LUDWIG RJ, VANHOORELBEKE K, LEYPOLDT F, KAYA Z, BIEBER K, MCLACHLAN SM, KOMOROWSKI L, LUO J, CABRAL-MARQUES O, HAMMERS CM, LINDSTROM JM, LAMPRECHT P, FISCHER A, RIEMEKASTEN G, TERSTEEG C, SONDERMANN P, RAPOPORT B, WANDINGER KP, PROBST C, EL BEIDAQ A, SCHMIDT E, VERKMAN A, MANZ RA and NIMMERJAHN F (2017) Mechanisms of Autoantibody-Induced Pathology. Frontiers in Immunology 8: 603. doi: 10.3389/fimmu.2017.00603. PMID: 28620373

LOWRIE M, HADJIVASSILIOU M, SANDERS DS and GARDEN OA (2016) A presumptive case of gluten sensitivity in a border terrier: a multisystem disorder? Veterinary Record 179 (22): 573. doi: 10.1136/vr.103910. PMID: 27784836

SINGH Y, GARDEN OA, LANG F and COBB BS (2016) Retroviral transduction of helper T cells as a genetic approach to study mechanisms controlling their differentiation and function. Journal of Visualized Experiments Nov 4 (117): doi 10.3791/54698. PMID: 27842353

LOWRIE M, HADJIVASSILIOU M, SANDERS DS and GARDEN OA (2016) A presumptive case of gluten sensitivity in a Border terrier: a multisystem disorder? Veterinary Record Oct 26: doi 10.1136/vr.103910. PMID: 27784836

GIULIANO A, SWIFT R, ARTHURS C, MAROTE G, ABRAMO F, McKAY J, THOMSON C, BELTRAN M, MILLAR M, PRIESTNALL S, DOBSON J, COSTANTINO-CASAS F, PETROU T, McGONNELL IM, DAVIES AJ, WEETMAN M, GARDEN OA, MASTERS JR, THRASIVOULOU C and AHMED A (2016) Quantitative expression and co-localization of Wnt signalling related proteins in feline squamous cell carcinoma. PLOS ONE 11 (8): e0161103. PMID: 27559731

FORTUNA L, RELF J, CHANG YM, HIBBERT A, MARTINEAU HM and GARDEN OA (2016) Prevalence of FoxP3+ cells in canine tumours and lymph nodes correlates positively with glucose transporter 1 expression. Journal of Comparative Pathology 155: 171-180. PMID: 27435834

MARCONATO L, POLTON GA, SABATTINI S, DACASTO M, GARDEN OA, GRANT I, HENDRICKX T, HENRIQUES J, LUBAS G, MORELLO E, STEFANELLO D and COMAZZI S; EUROPEAN CANINE LYMPHOMA NETWORK (2016) Conformity and controversies in the diagnosis, staging and follow-up evaluation of canine nodal lymphoma: a systematic review of the last 15 years of published literature. Veterinary and Comparative Oncology Jul 14: doi 10.1111.vco.12244. PMID: 27412493

SINGH Y, GARDEN OA, LANG F and COBB BS (2016) miRNAs regulate T cell production of IL-9 and identify hypoxia inducible factor-2α (HIF-2α) as an important regulator of Th9 and Treg differentiation. Immunology Jun 9: doi 10.1111/imm.12631. PMID: 27278750

AGUIAR J, CHANG YM and GARDEN OA (2016) Complications of percutaneous endoscopic gastrostomy in dogs and cats receiving corticosteroid treatment. Journal of Veterinary Internal Medicine May 23: doi 10.1111/jvim.13969. PMID: 27214641

COMAZZI S, AVERY PR, GARDEN OA, RIONDATO F, RUTGEN B and VERNAU,W, European Canine Lymphoma Network (2016) European canine lymphoma network consensus recommendations for reporting flow cytometry in canine hematopoietic neoplasms. Cytometry B Clinical Cytometry May 12: doi 10.1002/cyto.b.21382. PMID: 27170500

SWANN JW and GARDEN OA (2016) Novel immunotherapies for immune-mediated haemolytic anaemia in dogs and people. Veterinary Journal 207: 13-19. PMID: 27152382

CARNEY K, CHANG YM, WILSON S, CALNAN C, REDDY PS, CHAN WY, GILMARTIN T, HERNANDEZ G, SCHAFFER L, HEAD SR, MORLEY J, de MESTRE A, AFFLECK K and GARDEN, OA (2016) Regulatory T-cell-intrinsic amphiregulin is dispensable for suppressive function. Journal of Allergy and Clinical Immunology 137 (6): 1907-1909. PMID: 27040371

DENYER MP, PINHEIRO DY, GARDEN OA and SHEPHERD AJ (2016) Missed, not missing: phylogenomic evidence for the existence of avian FoxP3. PLOS ONE 11 (3): e0150988. PMID: 26938477

CHANG YM, HADOX E, SZLADOVITS B and GARDEN OA (2016) Serum biochemical phenotypes in the domestic dog . PLOS ONE 11 (2): e0149650. PMID: 26910479

PETERS LM, GLANEMANN B, GARDEN OA and SZLADOVITS B (2015) Cytological findings of 140 bile samples from dogs and cats and associated clinical pathological data. Journal of Veterinary Internal Medicine 30 (1): 123-131. PMID: 26566964

SINGH Y, GARDEN OA, LANG F and COBB BS (2015) MicroRNA-15b/16 enhances the induction of regulatory T cells by regulating the expression of Rictor and mTOR. Journal of Immunology 195 (12): 5667-5677. PMID: 26538392

LOWRIE M, GARDEN OA, HADJIVASSILOU M, HARVEY RJ, SANDERS DS, POWELL R and GAROSI L (2015) The clinical and serological effect of a gluten-free diet in Border terriers with epileptoid cramping syndrome. Journal of Veterinary Internal Medicine 29 (6): 1564-1568. PMID: 26500168

SWANN JW, PRIESTNALL SL, DAWSON C, CHANG YM and GARDEN OA (2015) Histologic and clinical features of primary and secondary vasculitis: a retrospective study of 42 dogs (2004-2011). Journal of Veterinary Diagnostic Investigation 27 (4): 489-496. PMID: 26077546

SCHMITZ S, GLANEMANN B, GARDEN OA, BROOKS H, CHANG YM, WERLING D and ALLENSPACH K (2015) A prospective, randomized, blinded, placebo-controlled pilot study on the effect of Enterococcus faecium on clinical activity and intestinal gene expression in canine food-responsive chronic enteropathy. Journal of Veterinary Internal Medicine 29 (2): 533-543. PMID: 25776251

LUO J and LINDSTROM J (2015) AChR-specific immunosuppressive therapy of myasthenia gravis. Biochemical Pharmacology. 97:609-619. doi: 10.1016/j.bcp.2015.07.011. PMID: 26215875

PINHEIRO D, CHANG YM, BRYANT H, SZLADOVITS B, DALESSANDRI T, DAVISON LJ, YALLOP E, MILLS E, LEO C, LARA A, STELL A, POLTON G and GARDEN OA (2014) Dissecting the regulatory microenvironment of a large animal model of non-Hodgkin lymphoma: evidence of a negative prognostic impact of FOXP3+ T cells in canine B cell lymphoma. PLOS ONE 9 (8): e105027. PMID: 25119018

ANFINSEN KP, PIERCY RJ, MASSEY C, SMITH KC, KENNY PJ and GARDEN OA (2014) Severe systemic calciphylaxis in a young cat. Journal of Veterinary Internal Medicine 28 (4): 1325-1330. PMID: 24903891

HARDY JI, HENDRICKS A, LOEFFLER A, CHANG YM, VERHEYEN KL, GARDEN OA and BOND R (2014) Food-specific serum IgE and IgG reactivity in dogs with and without skin disease: lack of correlation between laboratories. Veterinary Dermatology 25 (5): 447-e70. PMID: 24890097

FERREIRA C, PALMER D, BLAKE K, GARDEN OA and DYSON J (2014) Reduced regulatory T cell diversity in NOD mice is linked to early events in the thymus. Journal of Immunology 192 (9): 4145-4152. PMID: 24663675

LUO J and LINDSTROM JM (2014) Antigen-specific immunotherapeutic vaccine for experimental autoimmune myasthenia gravis. Journal of Immunology 193:5044-5055. doi: 10.4049/immunol. 1401392. PMID: 25288571

LAWRENCE J, CHANG YM, SZLADOVITS B, DAVISON LJ and GARDEN OA (2013) Breed-specific hematological phenotypes in the dog: a natural resource for the genetic dissection of hematological parameters in a mammalian species. PLOS ONE 8 (11): e81288. PMID: 24282579

WALKER D, KNUCHEL-TAKANO A, McCUTCHAN A, CHANG YM, DOWNES C, MILLER S, STEVENS K, VERHEYEN K, PHILLIPS AD, MIAH S, TURMAINE M, HIBBERT A, STEINER JM, SUCHODOLSKI JS, MOHAN K, EASTWOOD J, ALLENSPACH K, SMITH K and GARDEN OA (2013) A comprehensive pathological survey of duodenal biopsies from dogs with diet-responsive chronic enteropathy. Journal of Veterinary Internal Medicine 27 (4): 862-874. PMID: 23663231

KIDDER D, RICHARDS HE, ZILTENER HJ, GARDEN OA and CROCKER PR (2013) Sialoadhesin ligand expression identifies a subset of CD4+Foxp3- T cells with a distinct activation and glycosylation profile. Journal of Immunology 190 (6): 2593-2602. PMID: 23408841

BURR SP, DAZZI F and GARDEN OA (2013) Mesenchymal stromal cells and regulatory T cells: the Yin and Yang of peripheral tolerance? Immunology and Cell Biology 91 (1): 12-18. PMID: 23146942

SOOND DR, SLACK EC, GARDEN OA, PATTON DT and OKKENHAUG K (2012) Does the PI3K pathway promote or antagonize regulatory T cell development and function? Frontiers in Immunology 3: 244. PMID: 22912633

SOOND DR, GARCON F, PATTON DT, ROLF J, TURNER M, SCUDAMORE C, GARDEN OA and OKKENHAUG K (2012) Pten loss in CD4+ T cells enhances their helper function but does not lead to autoimmunity or lymphoma. Journal of Immunology 188 (12): 5935-5943. PMID: 22611241

LEWIS DH, CHAN DL, PINHEIRO D, ARMITAGE-CHAN E and GARDEN OA (2012) The immunopathology of sepsis: pathogen recognition, systemic inflammation, the compensatory anti-inflammatory response and regulatory T cells. Journal of Veterinary Internal Medicine 26 (3): 457-482. PMID: 22428780

SCHMITZ S, GARDEN OA, WERLING D and ALLENSPACH K (2012) Gene expression of selected signature cytokines of T cell subsets in duodenal tissues of dogs with and without inflammatory bowel disease. Veterinary Immunology and Immunopathology 146 (1): 87-91. PMID: 22333286

LUO J and LINDSTROM J (2012) Myasthenogenicity of the main immunogenic region and endogenous muscle nicotinic acetylcholine receptors. Autoimmunity. 45:245-252. doi: 10.3109/08916934.2011.622015. PMID: 21950318

SINGH Y, DYSON J and GARDEN OA (2011) Use of SNARF-1 to measure murine T cell proliferation in vitro and its application in a novel regulatory T cell suppression assay. Immunology Letters 140 (1-2): 21-29. PMID: 21664378

KATHRANI A, SCHMITZ S, PRIESTNALL SL, SMITH KC, WERLING D, GARDEN OA and ALLENSPAC K (2011) CD11c+ cells are significantly decreased in the duodenum, ileum and colon of dogs with inflammatory bowel disease. Journal of Comparative Pathology 145 (4): 359-366. PMID: 21592490

GARDEN OA, PINHEIRO DY and CUNNINGHAM F (2011) All creatures great and small: regulatory T cells in mice, humans, dogs and other domestic animal species. International Immunopharmacology 11 (5): 576-588. PMID: 21093606

PINHEIRO D, SINGH Y, GRANT C, APPLETON RC, SACCHINI F, WALKER KRL, CHADBOURNE AH, PALMER CA, ARMITAGE-CHAN E, THOMPSON I, WILLIAMSON L, CUNNINGHAM F and GARDEN OA (2011) Phenotypic and functional characterisation of a CD4+CD25highFOXP3high regulatory T cell population in the dog. Immunology 132 (1): 111-122. PMID: 20880379

BAILEY S, BENIGNI L, EASTWOOD J, GARDEN OA, McMAHON L, SMITH K, STEINER JM, SUCHODOLSKI JS and ALLENSPACH K (2010) Comparisons between cats with normal and increased fPLI concentrations in cats diagnosed with inflammatory bowel disease. Journal of Small Animal Practice 51 (9): 484-489. PMID: 21050218

SINGH Y, FERREIRA C, CHAN AC, DYSON J and GARDEN OA (2010) Restricted TCR-alpha CDR3 diversity disadvantages natural regulatory T cell development in the B6.2.16 beta chain transgenic mouse. Journal of Immunology 185 (6): 3408-3416. PMID: 20713881

GAJANAYAKE I, PRIESTNALL SL, BENIGNI L, ENGLISH K, SUMMERS B and GARDEN OA (2010) Paraneoplastic hypercalcemia in a dog with benign renal angiomyxoma. Journal of Veterinary Diagnostic Investigation 22 (5): 775-780. PMID: 20807942

ALLENSPACH K, HOUSE A, SMITH K, MNNEILL FM, HENDRICKS A, ELSON-RIGGINS J, RIDDLE A, STEINER JM, WERLING D, GARDEN OA, CATCHPOLE B and SUCHODOLSKI JS (2010) Evaluation of mucosal bacteria and histopathology, clinical disease activity and expression of Toll-like receptors in German shepherd dogs with chronic enteropathies. Veterinary Microbiology 146 (3-4): 326-335. PMID: 20615633

CARLUCCI F, FOSSATI-JIMACK L, DUMITRIU IE, HEIDARI Y, WALPORT MJ, SZAJNA M, BARUAH P, GARDEN OA, COOK HT and BOTTO M (2010) Identification and characterization of a lupus suppressor 129 locus on chromosome 3. Journal of Immunology 184 (11): 6256-6265. PMID: 20435933

LUO J, KURYATOV A and LINDSTROM JM (2010) Specific immunotherapy of experimental myasthenia gravis by a novel mechanism. Annals of Neurology 67:441-451. doi: 10.1002/ana.21901. PMID: 20437579

FERREIRA C, SINGH Y, FURMANSKI AL, WONG FS, GARDEN OA and DYSON J (2009) Non-obese diabetic mice select a low-diversity repertoire of natural regulatory T cells. Proceedings of the National Academy of Sciences (USA) 106 (20): 8320-8325. PMID: 19359477

KATHRANI A, STEINER JM, SUCHODOLSKI J, EASTWOOD J, SYME H, GARDEN OA and ALLENSPACH K (2009) Elevated canine pancreatic lipase immunoreactivity concentration in dogs with inflammatory bowel disease is associated with a negative outcome. Journal of Small Animal Practice 50 (3): 126-132. PMID: 19261082

KOHLHAAS S, GARDEN OA, SCUDAMORE C, TURNER M, OKKENHAUG K and VIGORITO E (2009) Cutting Edge: the Foxp3 target miR-155 contributes to the development of regulatory T cells. Journal of Immunology 182 (5): 2578-2582 (dual first authorship). PMID: 19234151

LUO J, TAYLOR P, LOSEN M, DE BAETS MH, SHELTON GD and LINDSTROM J (2009) Main immunogenic region structure promotes binding of conformation-dependent myasthenia gravis autoantibodies, nicotinic acetylcholine receptor conformation maturation, and agonist sensitivity. Journal of Neuroscience 29:13898-13908. doi: 10.1523/JNEUROSCI.2833-09.2009. PMID: 19890000

HASLAM SM, JULIEN S, BURCHELL JM, MONK CR, CERONI A, GARDEN OA and DELL A (2008) Characterizing the glycome of the mammalian immune system. Immunology and Cell Biology 86 (7): 564-573. PMID: 18725885

ISAACS JD, GARDEN OA, KAUR G, COLLINGE J, JACKSON GS and ALTMANN DM (2008) The cellular prion protein is preferentially expressed by CD4+ CD25+ Foxp3+ regulatory T cells. Immunology 125 (3): 313-319. PMID: 18462346

YATES J, ROVIS F, MITCHELL P, AFZALI B, TSANG JY, GARIN M, LECHLER RI, LOMBARDI G and GARDEN OA (2007) The maintenance of human CD4+ CD25+ regulatory T cell function: IL-2, IL-4, IL-7 and IL-15 preserve optimal suppressive potency in vitro. International Immunology 19: 785-799. PMID: 17545278

LINDSTROM J, LUO J and KURYATOV A (2007) MG and the tops and bottoms of AChRs: antigenic structure of the MIR and specific immunosuppression of EAMG using AChR cytoplasmic domains. Annals of the New York Academy of Sciences 1132:29-41. doi: 10.1196/annals.1405.007. PMID: 18567851

GARDEN OA, REYNOLDS PR, YATES J, LARKMAN DJ, MARELLI-BERG FM, HASKARD DO, EDWARDS AD and GEORGE AJT (2006) A rapid method for labelling CD4+ T cells with ultrasmall paramagnetic iron oxide nanoparticles for magnetic resonance imaging that preserves proliferative, regulatory and migratory behaviour in vitro. Journal of Immunological Methods 314 (1-2): 123-133. PMID: 16860821

PATTON DT, GARDEN OA, PEARCE WP, CLOUGH LE, MONK CR, LEUNG E, ROWAN WC, SANCHO S, WALKER LS, VANHAESEBROECK B and OKKENHAUG K (2006) Cutting edge: the phosphoinositide 3-kinase p110 delta is critical for the function of CD4+CD25+Foxp3+ regulatory T cells. Journal of Immunology 177: 6598-6602. PMID: 17082571

MONK CR, SUTTON-SMITH M, DELL A and GARDEN OA (2006) Preparation of CD25+ and CD25- CD4+ T cells for glycomic analysis--a cautionary tale of serum glycoprotein sequestration. Glycobiology 16: 11G-13G. PMID: 16770844

GARDEN OA, REYNOLDS PR, YATES J, LARKMAN DJ, MARELLI-BERG FM, HASKARD DO, EDWARDS AD and GEORGE AJ (2006) A rapid method for labelling CD4+ T cells with ultrasmall paramagnetic iron oxide nanoparticles for magnetic resonance imaging that preserves proliferative, regulatory and migratory behaviour in vitro. Journal of Immunological Methods 314: 123-133. PMID: 16860821

MONK CR, SPACHIDOU M, ROVIS F, LEUNG E, BOTTO M, LECHLER RI and GARDEN OA (2005) MRL/Mp CD4+,CD25- T cells show reduced sensitivity to suppression by CD4+,CD25+ regulatory T cells in vitro: a novel defect of T cell regulation in systemic lupus erythematosus. Arthritis and Rheumatism 52: 1180-1184. PMID: 15818683

ROVIS F, WAIT R, LEE BBC, MONK CR, LECHLER RI and GARDEN OA (2004) Proteomic characterization of murine CD4+CD25+ regulatory T cells. Immunology 2004. Vol. ISBN 88-7587-069-1, pp. 79-84. Bologna: Medimond Srl.

LECHLER RI, GARDEN OA and TURKA LA (2003) The complementary roles of deletion and regulation in transplantation tolerance. Nature Reviews in Immunology 3: 147-158. PMID: 12563298

GARDEN OA (2001) Genetic modelling of intestinal disease: the paradigm of gluten-sensitive enteropathy in the Irish setter dog – a model for human coeliac disease? The European Journal of Comparative Gastroenterology 10: 2-12.

RICH IN, WORTHINGTON-WHITE D, GARDEN OA and MUSK P (2000) Apoptosis of leukemic cells accompanies reduction in intracellular pH after targeted inhibition of the Na+/H+ exchanger. Blood 95: 1427-1434. PMID: 10666221

GARDEN OA, PIDDUCK H, LAKHANI KH, WALKER D, WOOD JL and BATT RM (2000) Inheritance of gluten-sensitive enteropathy in Irish Setters. American Journal of Veterinary Research 61: 462-468. PMID: 10772115

GARDEN OA, MUSK P, WORTHINGTON-WHITE DA, DEWEY MJ and RICH IN (2000) Silent polymorphisms within the coding region of human sodium/hydrogen exchanger isoform-1 cDNA in peripheral blood mononuclear cells of leukemia patients: A comparison with healthy controls. Cancer Genetics and Cytogenetics 120: 37-43. PMID: 10913675