Our current research focuses on the role of regulatory cells of lymphoid and myeloid origin in the pathogenesis of cancer and autoimmune disease.
We love dogs, not only because they are wonderful companions and members of our own families, but also because natural canine diseases offer insightful models for a plethora of human diseases -- and studying canine disease can help both dogs and humans, embracing our over-arching ethos of One Health, One Medicine.
It is something that we at Penn Vet take very seriously!
We have ongoing research on canine regulatory T cells and myeloid-derived suppressor cells in various canine cancers, including diffuse large B cell lymphoma, and autoimmune diseases, including immune-mediated haemolytic anaemia.
One of our exciting new areas of research is the influence of the intestinal microbiome, a key component of the exposome, on the pathogenesis of autoimmune disease and cancer in dogs. Stay tuned for more in due course!
We collaborate widely, within both the veterinary and biomedical research communities, and would be keen to hear from you if you would like to reach out with a proposal for a collaboration, or just for a chat about your complementary research activities over a coffee.
The following figure summarises our current research themes. We very much hope that you enjoy reading a little about what we do on the pages of this site, but do get in touch if you would like to learn more about our latest research: it is evolving month by month!