Characterization and validation of animal models of disease play a crucial role in our effort to understand and cure human disorders. Recognition and proper interpretation of the clinicopathological endpoints in experimental animals are essential to achieve a better understanding of their preclinical relevance and translational potential.
The Comparative Pathology Core (CPC), an Abramson Cancer Center shared resource, was created with the specific aim of providing expert pathological characterization and validation of preclinical animal models used in biomedical research.
The CPC currently supports several major research lines within the University of Pennsylvania and closely related institutes such as the Abramson Cancer Center, the Children's Hospital of Philadelphia and the Wistar Institute. Particular emphasis is given to the comparative pathology of genetically engineered mouse models in the context of both basic and translational research.
To pursue this mission, the CPC offers the expertise of board-certified veterinary pathologists, access to a state-of-the-art histology and immunohistochemistry service, and a thorough comparative pathology pipeline that ensures accurate interpretation of pathological changes developed in a wide range of experimental settings.
Using Our Services
For more information about our services, fees, and scheduling, please contact Dr. Amy Durham (email@example.com).