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Laminitis Research, New Bolton

Surgery Research


New Bolton Center's Surgery faculty are actively engaged in innovative research, including stem cell therapy, bone growth and regeneration, and stimulating the synthesis of cartilage components in the treatment of equine arthritis, positioning New Bolton and Penn Vet as an international leader in the field of equine musculoskeletal research.

In addition, New Bolton Center's Laminitis Research Laboratory, combining the work of Hannah Galantino-Homer, VMD-PhD, and Andrew van Eps, BVSc, PhD, DACVIM, associate professor of Equine Musculoskeletal Research, have  made significant inroads with regards to the cause of laminitis and potential preventatives.


Our Research Initiatives

New Bolton Center's Surgery faculty are actively engaged in groundbreaking research, including stem cell therapy, bone growth and regeneration, and stimulating the synthesis of cartilage components in the treatment of equine arthritis.

  • Ortved Orthopedic Regenerative Medicine Laboratory

    Joint injuries are overwhelmingly common in both human and equine athletes. Chondrocytes, the sole cell type in cartilage, are responsible for producing and maintaining the extra-cellular matrix (ECM), which affords remarkable tensile and compressive strength to the joint surface. Once damaged, cartilage has little to no ability to heal itself. Therefore, post-traumatic osteoarthritis (PTOA) commonly develops following joint trauma, whether sustained during an acute injury or accumulated overtime.

    Lab Mission

    • To improve cartilage repair using stem cell and gene therapy.
    • To limit the long-term effects of joint trauma through gene therapy immunomodulation of the joint.
    • To further elucidate the pathogenesis of post-traumatic osteoarthritis (PTOA).
        Read More About The Ortved Orthopedic Regenerative Medicine Laboratory
  • van Eps Laminitis Laboratory

    The van Eps Laminitis and Endocrinology Laboratory at New Bolton Center is focused on understanding the key events that drive laminitis under different circumstances in order to develop reliable means of prevention and treatment.  

    We take a multidisciplinary approach to the study of laminitis utilizing 

    • Advanced imaging and sensor-based techniques to evaluate structure and function of the foot in health and disease 
    • Molecular techniques to examine events at a tissue level. 
    • Biomechanical testing to study mechanical function both in vivo and ex vivo 

    We are also focused on developing and refining tests and novel biomarkers of endocrine dysfunction, the most common cause of laminitis in horses and ponies.

    More about the van Eps Lab

    Read More About The van Eps Laminitis Laboratory