SCWT Open Registry and DNA Bank. See www.scwtca.org.
For submission of DNA samples for the SCWT PLN-associated variant alleles, see www.scwtca.org/health/dnatest.htm
The Open Registry was begun in 1997, with updates every 1-2 years. Update 2011 has 1000+ dogs listed with PLE (protein-losing enteropathy), PLN (protein-losing nephropathy), combined PLE/PLN, juvenile renal disease/renal dysplasia, inflammatory bowel disease, and/or Addison's disease, the genetic diseases to which this breed is predisposed. Our SCWT DNA Bank has 600+ samples (affected and geriatric SCWT).
Littman Meryl P, Wiley Claire A, Raducha Michael G, Henthorn Paula S Glomerulopathy and mutations in NPHS1 and KIRREL2 in soft-coated Wheaten Terrier dogs. Mammalian Genome 24: 119-126, 2013.Littman MP State-of-the-Art-Review: Lyme nephritis J Vet Emerg Crit Care 23: 163-173, 2013.Littman MP Protein-losing Nephropathy in Small Animals Vet Clin N Am (Small Animal) 41: 31-62, 2011.Slade Dennis J, Lees George E, Berridge Brian R, Clubb Fred J, Kuczynski Leslie A, Littman Meryl P Resolution of a proteinuric nephropathy associated with Babesia gibsoni infection in a dog. Journal of the American Animal Hospital Association 47: e138-44, 2011.Littman MP A Matter of Opinion: Should we treat asymptomatic, nonproteinuric Lyme-seropositive dogs with antibiotics? Clinician’s Brief 9: 13-16, 2011.Littman MP Diagnosis of infectious diseases of the urinary tract Nephrology and Urology of Small Animals : 241-252, 2011.Littman MP, Wagner S, Hammer C Preventive Health Programs Clinical Textbook for Veterinary Technicians, 7th ed. : , 2009.Littman MP, Goldstein RE, Labato MA, Lappin MR, Moore GE ACVIM Small Animal Consensus Statement on Lyme Disease in Dogs: Diagnosis, Treatment, and Prevention J Vet Intern Med 20: 422-434, 2006.Littman Meryl P Canine borreliosis. The Veterinary clinics of North America. Small animal practice 33: 827-62, 2003.Littman M P, Dambach D M, Vaden S L, Giger U Familial protein-losing enteropathy and protein-losing nephropathy in Soft Coated Wheaten Terriers: 222 cases (1983-1997). Journal of veterinary internal medicine / American College of Veterinary Internal Medicine 14: 68-80, 2000.
AB (Biology) Bryn Mawr College, 1972VMD (Veterinary Medicine) University of Pennsylvania, 1975Qualified, American College of Veterinary Internal Medicine (ACVIM)
Board Certified, Diplomate of the American College of Veterinary Internal Medicine (DACVIM)