New Bolton Center Kennett Square, PA
Emergencies & Appointments:
Ryan Hospital Philadelphia, PA


Qualified, American College of Veterinary Internal Medicine (ACVIM)

Board Certified, Diplomate of the American College of Veterinary Internal Medicine (DACVIM)

Clinical Specialties: Internal Medicine,
Research Areas: Canine tick-borne diseases, Canine protein-losing nephropathy, Canine protein-losing enteropathy, inflammatory bowel disease, Addison's disease, Soft coated Wheaten Terrier Open Registry and DNA Bank
PubMed Link
Contact Information:
University of Pennsylvania
School of Veterinary Medicine
3900 Delancey Street

SCWT Open Registry and DNA Bank. See

For submission of DNA samples for the SCWT PLN-associated variant alleles, see

The Open Registry was begun in 1997, with updates every 1-2 years. Update 2011 has 1000+ dogs listed with PLE (protein-losing enteropathy), PLN (protein-losing nephropathy), combined PLE/PLN, juvenile renal disease/renal dysplasia, inflammatory bowel disease, and/or Addison's disease, the genetic diseases to which this breed is predisposed. Our SCWT DNA Bank has 600+ samples (affected and geriatric SCWT).

Littman Meryl P, Wiley Claire A, Raducha Michael G, Henthorn Paula S Glomerulopathy and mutations in NPHS1 and KIRREL2 in soft-coated Wheaten Terrier dogs. Mammalian Genome 24: 119-126, 2013.

Littman MP State-of-the-Art-Review: Lyme nephritis J Vet Emerg Crit Care 23: 163-173, 2013.

Littman MP Protein-losing Nephropathy in Small Animals Vet Clin N Am (Small Animal) 41: 31-62, 2011.

Slade Dennis J, Lees George E, Berridge Brian R, Clubb Fred J, Kuczynski Leslie A, Littman Meryl P Resolution of a proteinuric nephropathy associated with Babesia gibsoni infection in a dog. Journal of the American Animal Hospital Association 47: e138-44, 2011.

Littman MP A Matter of Opinion: Should we treat asymptomatic, nonproteinuric Lyme-seropositive dogs with antibiotics? Clinician’s Brief 9: 13-16, 2011.

Littman MP Diagnosis of infectious diseases of the urinary tract Nephrology and Urology of Small Animals : 241-252, 2011.

Littman MP, Wagner S, Hammer C Preventive Health Programs Clinical Textbook for Veterinary Technicians, 7th ed. : , 2009.

Littman MP, Goldstein RE, Labato MA, Lappin MR, Moore GE ACVIM Small Animal Consensus Statement on Lyme Disease in Dogs: Diagnosis, Treatment, and Prevention J Vet Intern Med 20: 422-434, 2006.

Littman Meryl P Canine borreliosis. The Veterinary clinics of North America. Small animal practice 33: 827-62, 2003.

Littman M P, Dambach D M, Vaden S L, Giger U Familial protein-losing enteropathy and protein-losing nephropathy in Soft Coated Wheaten Terriers: 222 cases (1983-1997). Journal of veterinary internal medicine / American College of Veterinary Internal Medicine 14: 68-80, 2000.

AB (Biology) Bryn Mawr College, 1972

VMD (Veterinary Medicine) University of Pennsylvania, 1975

Qualified, American College of Veterinary Internal Medicine (ACVIM)

Board Certified, Diplomate of the American College of Veterinary Internal Medicine (DACVIM)