JOHN D. GEARHART
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New Bolton Center Kennett Square, PA
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610-444-5800
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Ryan Hospital Philadelphia, PA
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215-746-8911
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Biomedical Sciences Faculty



Historically, the Department of Biomedical Sciences is recognized as one of the premier basic science departments in veterinary medicine and research conducted here has had a major global impact on experimental biology and medicine. Biomedical Sciences anchors veterinary education within the larger context of one medicine and tightly links the School with Penn's biomedical community.

JOHN D. GEARHART, Ph.D., M.Sc., B.Sc.

Professor, Department of Biomedical Sciences, University of Pennsylvania School of Veterinary Medicine

Research Areas: Regenerative medicine, Stem Cells
PubMed Link
Contact Information:
9-121 Smilow Center for Translational Research
3400 Civic Center Blvd.

Pashai Nikta, Hao Haiping, All Angelo, Gupta Siddharth, Chaerkady Raghothama, De Los Angeles Alejandro, Gearhart John D, Kerr Candace L Genome-wide profiling of pluripotent cells reveals a unique molecular signature of human embryonic germ cells. PloS one 7: e39088, 2012.

Chaerkady Raghothama, Letzen Brian, Renuse Santosh, Sahasrabuddhe Nandini A, Kumar Praveen, All Angelo H, Thakor Nitish V, Delanghe Bernard, Gearhart John D, Pandey Akhilesh, Kerr Candace L Quantitative temporal proteomic analysis of human embryonic stem cell differentiation into oligodendrocyte progenitor cells. Proteomics 11: 4007-20, 2011.

Esteso P, Gearhart J D The use of human embryonic stem cells in drug discovery. Counterpoint. Clinical pharmacology and therapeutics 89: 641-3, 2011.

Gearhart, J. and Coutifaris, C. In vitro fertilization, the Nobel Prize, and human embryonic stem cells. Cell Stem Cell 8: , 2011.

Maragh Samantha, Miller Ronald A, Bessling Seneca L, McGaughey David M, Wessels Marja W, de Graaf Bianca, Stone Eric A, Bertoli-Avella Aida M, Gearhart John D, Fisher Shannon, McCallion Andrew S Identification of RNA binding motif proteins essential for cardiovascular development. BMC Developmental Biology 11: 62, 2011.

Addis Russell C, Hsu Fu-Chun, Wright Rebecca L, Dichter Marc A, Coulter Douglas A, Gearhart John D Efficient conversion of astrocytes to functional midbrain dopaminergic neurons using a single polycistronic vector. PloS one 6: e28719, 2011.

Hiller Marc, Liu Cyndi, Blumenthal Paul D, Gearhart John D, Kerr Candace L Bone Morphogenetic Protein 4 Mediates Human Embryonic Germ Cell Derivation. Stem cells and development 20: 351-61, 2010.

Christoforou Nicolas, Oskouei Behzad N, Esteso Paul, Hill Christine M, Zimmet Jeffrey M, Bian Weining, Bursac Nenad, Leong Kam W, Hare Joshua M, Gearhart John D Implantation of mouse embryonic stem cell-derived cardiac progenitor cells preserves function of infarcted murine hearts. PloS one 5: e11536, 2010.

Kerr Candace L, Letzen Brian S, Hill Christine M, Agrawal Gracee, Thakor Nitish V, Sterneckert Jared L, Gearhart John D, All Angelo H Efficient differentiation of human embryonic stem cells into oligodendrocyte progenitors for application in a rat contusion model of spinal cord injury. The International journal of neuroscience 120: 305-13, 2010.

Chaerkady Raghothama, Kerr Candace L, Kandasamy Kumaran, Marimuthu Arivusudar, Gearhart John D, Pandey Akhilesh Comparative proteomics of human embryonic stem cells and embryonal carcinoma cells. Proteomics 10: 1359-73, 2010.

Ph.D. (Genetics and Development) Cornell University (Ithaca), 1970

M.Sc. (Plant Gentics) University of New Hampshire, 1966

B.Sc. (Ag Biological Sciences) The Pennsylvania State University, 1964