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Research Positions



Research Associate Position Available: A Research Associate position is available to study the role of inflammasome activation in innate and adaptive immune responses to Salmonella infection. Applicants must have a PhD degree and at least 4 years of post-doctoral experience working in animal models of bacterial infection, in vitro culture models of infection, and analysis of innate immune responses.

Additionally, experience in multi-parameter flow cytometry, working with inbred and transgenic mouse lines, and the generation and screening of bacterial transposon libraries is highly desired for this position.

The specific project areas and requirements for this position will involve (but are not limited to):

  1. Understanding innate and adaptive responses to oral Salmonella immunization and challenge
  2. Utilizing bacterial genetic screening approaches to identify Salmonella genes involved in inflammasome evasion
  3. Training graduate and undergraduate students in the lab
  4. Assisting with grant applications

Please email CV, description of previous work and references (three names and phone numbers) to Sarah Hughes, University of Pennsylvania, Philadelphia, PA, (donza@vet.upenn.edu).

AA/EOE. The University of Pennsylvania is an EOE. Minorities / Women / Individuals with disabilities / Protected Veterans are encouraged to apply.

Posted: May 4, 2016



Research Associate Position ​Available: The Herbert laboratory in the Department of Pathobiology at the University of Pennsylvania School of Veterinary medicine is seeking a highly motivated and energetic individual with a keen interest in mucosal immunity to fill a full-time Research Associate position starting July 1st, 2016.

The position will involve studying Type 2 immune responses in mouse models of allergic inflammatory disease of the airways and gut. There will be a particular emphasis on studying how the interactions between myeloid cells and epithelial cells at mucosal sites impact host immunity, tissue regeneration and wound repair. Projects are flexible, but must focus on topics relevant to mucosal immunology (e.g. Trefoil factor proteins) that will ideally generate the foundation for the candidate’s future independent career. The associate will be required to independently design and execute experiments and interpret results. The associate will also prepare scientific abstracts and manuscripts for conferences and peer-reviewed journals. The associate will be encouraged to attend and present at scientific meetings.

A PhD in immunology, molecular biology or biochemistry with additional years of experience working with various conditional and transgenic mice in models of allergic inflammatory disease, cell culture, cell-based assays, flow cytometry, PCR and RT-PCR is required. Solid experience with cell sorting, microscopy, bead-based luminex assays, western blotting, and immunohistochemistry is highly desired.

Prior experience with the isolation and culture of primary lung epithelia cell lineages (mTECs and ATII) isolated from mice is advantageous. Experience with isolation and culture of cells from human blood or tissue samples is helpful. Knowledge of work-flows involved in single-cell sequencing is an added advantage. Preference will be given to candidates with prior experience in using Buxco and/or Flexivent systems for mouse lung physiology and airway hyperresponsiveness measurements.The successful candidate must have a strong scientific track record as evidenced by papers published in high-impact peer-reviewed journals. The candidate must also possess excellent written and verbal communication skills. .

The associate will join the vibrant immunology community at UPenn, which encompasses broad expertise in basic immunology, host-pathogen interactions, allergy, inflammation, and tumor immunology. Maximal support will be provided to the associate for future grant applications and developing lines of future independent research.

Posted on February 17, 2016



Research Associate Position ​Available: A Research Associate Position is available to study the role of the immune response to ​Leishmania in both mice and humans. Applicants must have a PhD degree and extensive experience working with both mice and human cells.

Specific experience working with various inbred and transgenic mice, and in basic cellular immunology, flow cytometry (including analysis and cell sorting), PCR, and analysis of large data sets derived from gene transcriptional studies is required.

Additionally, experience working with pathogens, and with human tissues (skin) is highly desired for this position.

The specific project will focus on:

  • Defining the pathologic role of CD8 T cells in cutaneous ​Leishmaniasis
  • Identifying new approaches to block chronic inflammatory responses in cutaneous Leishmaniasis

Please email CV, description of previous work and references (three names and phone numbers) to Sarah Hughes, University of Pennsylvania, Philadelphia, PA, (donza@vet.upenn.edu).

AA/EOE. The University of Pennsylvania is an EOE. Minorities / Women / Individuals with disabilities / Protected Veterans are encouraged to apply. ​

Posted on ​March 8, 2016



A Research Associate position is available to study the role of endothelial cells in resistance to Toxoplasma gondii. Applicants must have a PhD degree and experience working with infectious disease and intravital imaging.

The specific project will focus on:

  1. The role of endothelial cells in resistance to T. gondii
  2. Utilizing imaging approaches to visualize immune cell populations during infection or vaccination
  3. Aiding others with learning and applying intravital imaging

Please email CV, description of previous work and references (three names and phone numbers) to Sarah Hughes, University of Pennsylvania, Philadelphia, PA, (donza@vet.upenn.edu).

AA/EOE. The University of Pennsylvania is an EOE. Minorities / Women / Individuals with disabilities / Protected Veterans are encouraged to apply.

Posting date: 2/2/16