Clinical Support Services

Cancer Clinical Trials

Many diseases that occur in humans are also recognized in non-human species, and cancer is one of these diseases. At Penn Vet, the Veterinary Clinical Investigations Center (VCIC) provides the infrastructure to facilitate the translation of novel interventions from basic scientists to high quality investigations with naturally occurring diseases that parallel human conditions.

At the Penn Vet Cancer Center, we are uniquely positioned to study the impact of cancer research breakthroughs through this approach, not with laboratory animals, but with patients themselves. Conventionally, new medical advancements move from experiments with laboratory animals directly to human clinical trials. In clinical trials at Penn Vet, our patients present with spontaneous diseases in the same way humans do. By studying the impact of research models through clinical trials in client-owned animals whose day-to-day lives more closely resemble our own, scientists and doctors can better understand the outcome of therapeutics in patients.

In addition, our patients can more immediately benefit from breakthrough research conducted in strict protocols and controlled settings.

 


Clinical Trials

CANCER - Trial for Dogs with Mast Cell Tumors, B Cell Lymphoma, or Histocytic Sarcoma

Seeking dogs with specific tumors to help us further cancer research.

active tumor sarcoma Oncology mct mast cell tumor lymphoma immunotherapy immune histiocytic sarcoma canine cancer b cell

OSTEOSARCOMA - Use of a Novel Immunotherapy for Dogs with Bone Cancer of the Leg

Further evaluation of the Listeria vaccine in dogs with osteosarcoma.

bacteria OSA vaccine osteosarcoma Mason Osteosarcoma mason Listeria cancer active cancer bone cancer active

TRANSITIONAL CELL CARCINOMA - Clinical Trial Using Immunotherapy For Female Dogs With Bladder Cancer

A modified Listeria vaccine for female dogs with bladder cancer.

cancer active transitional cell carcinoma TCC Mason TCC carcinoma Mason Active canine carcinoma canine bladder cancer bladder cancer in dogs bladder cancer active

Safety And Effectiveness Of Antibody Therapy For Dogs With Splenic Hemangiosarcoma

This trial evaluates the safety and effectiveness of an antibody therapy designed to inhibit VEGF and delay or prevent spread of hemangioscarcoma after surgery

cancer active Mason hemangiosarcoma Mason Cancer Studies Mason Active immunotherapy hemangiosarcoma canine hemangiosarcoma canine cancer cancer active

Use of Near-infrared Imaging in Surgical Accuracy for Feline Soft-Tissue Sarcomas

Penn Vet is conducting a study to determine if near-infrared imaging can improve the surgeon’s ability to see cancer and cancer margins during surgery to remove feline soft tissue sarcomas.

cancer active ryan surgery infrared imaging feline soft tissue sarcoma david holt active

FIBROSARCOMA - Trial of ALVAC® IL-2 Treatment in Cats with Feline Fibrosarcoma

Clinical trial evaluating surgery in combination with immunotherapy for cats with fibrosarcoma

cancer active VAS vaccine tumor surgery sarcoma FSA cancer active

Re-directed Autologous T cell Therapy for drug resistant or refractory CD20+ B cell lymphoma

Immune cells (known as T cells) are taken from the peripheral blood, stimulated, expanded and genetically modified in the laboratory to express a surface receptor that recognizes B cells

cancer active Mason lymphoma Mason Cancer Studies Mason Active mason immunotherapy canine lymphoma canine cancer cancer b-cell malignancies B-cell lymphoma active

RNA-transfected CD40-B Cell Vaccines for Dogs With Newly Diagnosed Lymphoma

Determine whether a cell based vaccine can prevent the return of lymphoma after standard chemotherapy treatment.

inactive Mason lymphoma Mason Cancer Studies Mason Active lymphoma immunotherapy canine lymphoma canine cancer cancer active cancer

HEMANGIOSARCOMA - Supplement for Dogs with Cancer of the Spleen

In this trial, we will be comparing I’m-Yunity’s® effect on survival time and quality of life to the standard chemotherapy treatment.

cancer active VCIC turkey tail mushroom splenic HSA spleen mushroom I’m-Yunity HSA hemangiosarcoma cancer alternative medicine active