Penn Vet | Clinical Trial Detail
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New Bolton Center Kennett Square, PA
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610-444-5800
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Ryan Hospital Philadelphia, PA
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215-746-8911
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215-746-8387
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HEMANGIOSARCOMA - Clinical evaluation of propranolol and doxorubicin for the treatment of splenic hemangiosarcoma in the dog

In this trial, we will be evaluating Propranolol’s effect on survival time and quality of life when given in combination with the standard chemotherapy treatment.

cancer center splenic HSA splenic hemangiosarcoma spleen propranolol PPL HSA hemangiosarcoma chemotherapy cancer active cancer active

OSTEOSARCOMA: Evaluation of Flash Proton RT in Dogs with Bone Cancer of the Leg

A new type of radiation therapy for dogs with appendicular osteosarcoma

cancer center radiation therapy leg tumor leg cancer large dog cancer large breed cancer bone tumor bone cancer amputation active

SARCOMA: Soft Tissue Sarcoma & Mammary Carcinoma - Photoacoustic System for Identifying Tumor Edges (PSITE)

cancer center tumor removal tumor soft tissue sarcoma mammary carcinoma cancer active

DERMATITIS - Randomized clinical trial to assess the utility of feline Interleukin-2 as an adjuvant to allergen vaccines, for the treatment of feline atopic dermatitis.

Novel Treatment for Feline Atopy

immunotherapy allergy shots allergy testing allergic dermatitis allergic dermatitis active scratching itching seasonal allergies itchy cats itchy atopy feline

CARDIO - Clinical trial for dogs with arrhythmogenic right ventricular cardiomyopathy (ARVC)

The goal of this study is to explore options for monitoring and treating arrhythmias in dogs with ARVC.

active cardiomyopathy ARVC arrhythmia

UVEITIS - Clinical & Safety Evaluation of SOCS1-KIR for the Treatment of Horses with Uveitis

This study evaluates the safety and effectiveness associated with the administration a new medication to positively impact comfort of the eye and prolong vision in horses diagnosed with unilateral or bilateral uveitis.

active vision in horses unilateral uveitis ophthalmology equine uveitis bilateral uveitis

DIABETES - Validation of the FreeStyle Libre flash glucose monitor in dogs and cats with diabetes mellitus

The primary aim of this study is to validate the FSL glucose monitoring system for the use in dogs and cats with diabetes.

blood glucose flash glucose monitoring system diabetes active

Myasthenia Gravis - Determination of pathological autoantibodies in dogs with myasthenia gravis

Blood collection to assist in development of a biomarker that predicts the severity and prognosis of myathenia gravis

active weakness Neurology myasthenia gravis muscle weakness acetylcholine receptors

IMMUNE-MEDIATED HEMOLYTIC ANEMIA OR THROMBOCYTOPENIA : Evaluating the intestinal microbiome as a possible trigger for IMHA in dogs

The purpose of this study is to investigate whether the bacterial population of the GI tract may be a contributing factor to the onset of immune-mediated hemolytic anemia or thrombocytopenia in dogs.

active immune-mediated hemolytic anemia IMHA anemia

MENINGIOMA - Study of two oral medications in treament of canine brain tumors

Evaluating safety and anti-cancer activity of oral PAC-1 used with hydroxyurea for canine meningioma

meningioma seizure brain tumor active

CARDIO - Clinical trial for dogs with atrial fibrillation

The goal of this study is to determine whether slowing down the heart rate in canine atrial fibrillation improves survival.

cardiac issue in dogs dog heart problem active canine atrial fibrilation

CANCER - Trial for Dogs with Mast Cell Tumors, B Cell Lymphoma, or Histocytic Sarcoma

Seeking dogs with specific tumors to help us further cancer research.

active tumor sarcoma Oncology mct mast cell tumor lymphoma immunotherapy immune histiocytic sarcoma canine cancer b cell

HEART MURMUR - New study evaluating a novel prescription diet for dogs with heart murmurs.

A study evaluating whether a new prescription diet will slow the progression of mitral valve disease in dogs.

bad heart dog heart failure ECG mitral valve disease heart murmur heart disease heart echocardiogram cardiology cardiac active

TRANSITIONAL CELL CARCINOMA - Clinical Trial Using Immunotherapy For Female Dogs With Bladder Cancer

A modified Listeria vaccine for female dogs with bladder cancer.

cancer active transitional cell carcinoma TCC Mason TCC carcinoma Mason Active canine carcinoma canine bladder cancer bladder cancer in dogs bladder cancer active

CRUCIATE TEAR - Clinical Trial for dogs who had a Cranial Cruciate Ligament (CCL) Rupture & TPLO Surgery

Assessing novel therapeutic that will be evaluated for its effect on the development and progression of osteoarthritis in dogs following CCL rupture and TPLO surgery

ligament ACL cruciate tear cruciate meniscal tear TPLO knee surgery CCL rupture CCL arthritis active

Coagulation in Septic Peritonitis in Dogs

We are testing a heparin derivative that is anti-inflammatory without being anticoagulant.

abdomen septic belly septic abdomen septic peritonitis active

Use of Near-infrared Imaging in Surgical Accuracy for Feline Soft-Tissue Sarcomas

Penn Vet is conducting a study to determine if near-infrared imaging can improve the surgeon’s ability to see cancer and cancer margins during surgery to remove feline soft tissue sarcomas.

cancer active ryan surgery infrared imaging feline soft tissue sarcoma david holt active

FIBROSARCOMA - Trial of ALVAC® IL-2 Treatment in Cats with Feline Fibrosarcoma

Clinical trial evaluating surgery in combination with immunotherapy for cats with fibrosarcoma

cancer active VAS vaccine tumor surgery sarcoma FSA cancer active

LYMPHOMA - Re-directed Autologous T cell Therapy for B cell lymphoma

Immune cells (known as T cells) are taken from the peripheral blood, stimulated, expanded and genetically modified in the laboratory to express a surface receptor that recognizes B cells

cancer center comprehensive cancer care Mason lymphoma Mason Cancer Studies Mason Active mason immunotherapy canine lymphoma canine cancer cancer active cancer b-cell malignancies B-cell lymphoma active

ARTHRITIS - Long term study assessing outcome of knee arthritis in dogs with cruciate ligament (CCL) rupture

A clinical trial evaluating the outcome of dogs with patellofemoral osteoarthritis due to the rupture of the Cranial Cruciate Ligament in one stifle, then stabilized with the Tibial Plateau Leveling Osteotomy (TPLO) procedure

arthritis limping stifle ACL cruciate VCIC TPLO tibial plateau leveling osteotomy osteoarthritis orthopedic ligament rupture knee joint cruciate tear cranial cruciate ligament CCL Agnello active