The VCIC is now enrolling twenty (20) dogs with perianal fistula(s) for a clinical trial assessing the clinical outcome of dogs with varying degrees of inflammation and irritation due to perianal fistulas. Dogs enrolled will be randomized to a new, one-time injection into the lesion(s) to help manage perianal fistulas and the corresponding symptoms.  All patients will also continue to receive standard-of-care therapy (oral cyclosporine), which will be tapered according to patient response. Patients will be require to attend eight (8) visits within 7 months to the University of Pennsylvania Veterinary Hospital.

Inclusion Criteria:

• Dogs 1-12 years of age
• Confirmed diagnosis of at least one perianal fistula
• Patient must be receiving continued oral cyclosporine for a minimum of 2 weeks prior to enrollment
• No evidence of significant clinical conditions/diseases
• No history of surgical intervention for the treatment of perianal fistula (including but not limited to: cryosurgery, anal sac resection, tail amputation)

Benefits:

• Financial coverage for scheduled study tests, medications, and all study visits
• Financial compensation for time and travel upon completion of all study visits

Contact:

If interested in enrolling your dog in this study, or would like to learn more, contact the VCIC at 215-573-0302 or vcic@vet.upenn.edu for more information about this or any of our other studies.