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Cryptosporidium and Childhood Illness

Symposium – Intestinal Infection & Immunity

New Science to tackle Diarrheal Disease in Small Children

Diarrheal diseases are responsible for ten percent of all mortality in children under-five world-wide and even milder forms of intestinal infection have a long lasting impact on the nutritional state, disease susceptibility and growth of children. These relationships are complex and the underlying mechanisms are not fully understood.

Significant advances have been made in protecting children from some of these infections through vaccination. Targeting emerging challenges, such as the protozoan parasite Cryptosporidium, is at the forefront of this effort.

This symposium will explore how recent scientific advances in microbiology, immunology, and medicine can be used to understand and ultimately solve this important global problem.

When & Where

  • Date: Monday, March 12, 2018
  • Time: 8:00 am - 1:30 pm
  • Location: Hill Pavillion, Rm. 131
    School of Veterinary Medicine
    University of Pennsylvania
    380 S. University Ave, Philadelphia, PA 19104

Featured Speakers

Yasmine Belkaid, NIH IRPYasmine Belkaid, National Institute of Health
"Nutritional and microbiota control of immunity to GI pathogens"
Carol Gilchrist
Carol Gilchrist, University of Virginia
"Genetic diversity of Cryptosporidium hominis in a Bangladeshi community"
Maayan Levy, PhD, Penn Medicine
Maayan Levy, Penn Medicine
"Intestinal cell function in host microbiome interactions"
paul-offit
Paul Offit, Children's Hospital of Philadelphia (CHOP) 
"The Rotavirus vaccine: From bench to bedside"
WPetriJr
William Petri, University of Virginia
"Cryptosporidiosis in infants in Bangladesh"
luning-prak.eline
Eline Luning Prak, Penn Medicine
"Antibody repertoire analysis in the human gastrointestinal tract"
Boris Striepen
Boris Striepen, Penn Vet
"Biology of Cryptosporidium-host interaction and immunity"
john-wherry
John Wherry, Penn Medicine
"Deep profiling of human vaccine and pathogen induced immunity"
Symposium Agenda, March 12, 2018
8:00am  -- Coffee --
8:30am "The Rotavirus Vaccine: From Bench to Bedside" 

Dr. Paul Offit 

  • Maurice R. Hilleman Chair of Vaccinology
  • Division of  Infectious Diseases
  • Children’s Hospital of Philadelphia
9:10am "Cryptosporidiosis in infants in Bangladesh: impact on growth, development and individual differences in susceptibility" 

Dr. Bill Petri

  • Wade Hampton Frost Professor of Medicine
  • Chief, Division of Infectious Diseases  
  • University of Virginia, School of Medicine
9:50am "Genetic diversity of Cryptosporidium hominis in a Bangladeshi community as revealed by whole genome sequencing" 

Dr. Carol Gilchrist 

  • Associate Professor
  • Infectious Diseases and International Health
  • University of Virginia, School of Medicine
10:10am "Intestinal cell function in host microbe interaction"

Dr. Maayan Levy

  • Assistant Professor, Department of Microbiology
  • University of Pennsylvania, Perelman School of Medicine
10:30am -- Break -- 
11:00am "Deep and specific immune profiling of human vaccine and pathogen induced immunity"

Dr. John Wherry

  • Richard and Barbara Schiffrin President’s Distinguished Professor of Microbiology  
  • Director, Institute for Immunology
  • University of Pennsylvania, Perelman School of Medicine
11:40am "Antibody repertoire analysis in the human gastrointestinal tract"

Dr. Eline Luning Prak 

  • Associate Professor, Department of Pathology and Laboratory Medicine 
  • University of Pennsylvania, Perelman School of Medicine
12:00pm "Biology of Cryptosporidium-host interaction and immunity"

Dr. Boris Striepen

  • Professor, Department of Pathobiology
  • University of Pennsylvania, School of Veterinary Medicine
12:40pm "Nutritional and microbiota control of immunity to GI pathogens"

Dr. Yasmine Belkaid

  • Chief Mucosal Immunology Section, Laboratory of Parasitic Diseases
  • National Institutes of Health

Sponsored Jointly:

  • Department of Pathobiology, Penn Vet
  • Center for Host-Microbial Interactions, Penn Vet
  • Institute for Translational Medicine and Therapeutics, Penn Medicine
  • Center for Global Health
  • Institute for Immunology