Research Newsletter | Spring 2024
Announcements
10 Ways Researchers Can Help Journalists Avoid Errors When Reporting on Academic Studies
This tip sheet outlines some of the many ways researchers can help the news media cover research accurately, starting with the journalists who interview them about their work.
Nature Masterclasses
Nature Masterclasses are professional development training classes for researchers. More than twenty on-demand courses are offered that can be completed on your schedule. Access to the courses is available to anyone with a PennKey.
Data Curation & DOI Creation: New Services from Penn Libraries ScholarlyCommons
ScholarlyCommons, Penn’s open-access institutional repository, is offering two new services: Data curation for smaller datasets and a DOI request process.
Data Curation Service
The data curation service allows you to submit your dataset for review prior to depositing it into ScholarlyCommons. Expert data curators review your dataset and documentation for ways to enhance the findability, accessibility, interoperability, and reusability. Researchers can then update their dataset according to the feedback before sharing it in ScholarlyCommons. Studies have found that data curation adds value to the data-sharing process and increases researchers’ confidence in sharing their data (Marsolek, 2023). The ScholarlyCommons data curation request form and more information can be found in the ScholarlyCommons Guide in the How to Request Data Curation instructions.
DOI Request Process
ScholarlyCommons now allows submitters to request a Digital Object Identifier (DOI) for an existing deposit. The repository already provides automatically assigned persistent identifiers in the form of Handles (labeled as permalinks on a record page), but there are circumstances where a DOI is desirable. The ScholarlyCommons DOI request form and more information can be found in the ScholarlyCommons Guide in the How to Request a DOI instructions.
Questions can be directed to libraryrepository@upenn.edu.
New Author Cost Agreements with Select Publishers
The Penn Libraries have signed new open-access agreements with Springer Publishing, the Company of Biologists, the Royal Society of Chemistry, and the Institute of Physics. Through these agreements, any Penn-affiliated author—including students, faculty, researchers, staff, and clinicians—is eligible to publish their research as an open-access article without fees. The open access fee waiver will align with the corresponding author, and it is recommended that authors use their Penn email when submitting to journals associated with these agreements. To learn more about the agreement, see the public announcement on the Penn Libraries website.
The Libraries have similar agreements with SAGE publishing, Wiley, Cambridge University Press, and a retroactive agreement with Elsevier to make Penn scholarship openly accessible from 1986-2000.
Authors can find additional guidance on publishing workflows, article requirements, and the scope of these agreements in the dedicated online portal. Helpful information can also be found on the Services for Authors page. Rebecca Stuhr, associate university librarian for academic engagement & director of arts and culture libraries, is also available to provide guidance and answer questions.
Looking for Undergraduate Research Assistants?
If you are looking for an undergraduate research assistant or are open to involving an undergraduate in your work, you can post an entry in the Center for Undergraduate Research and Fellowships (CURF) Research Directory. The directory allows interested students to identify and connect with Penn faculty mentors.
ORS Staff Contact Information
The Office of Research Services (ORS) webpage has been updated to include a more robust search functionality to find ORS Staff members’ contact information.
On the ORS homepage, select the “About Us” menu, and there are two options to search for ORS staff member contact information:
- Team Directory–Area of Service
- Team Directory–Department/Org
Updated Core Facilities Finder Video Presentations
The content on the Core Facilities Finder webpage has been refreshed. The page is designed to be a go-to resource for both core facility directors and potential customers. In conjunction with this refresh, core facility video presentations are now available as a resource to share with interested users.
Please contact April Weakley (aweakley@pennmedicine.upenn.edu) if you would like to provide updates or additional content.
Join Penn Vet’s Artificial Intelligence Interest Group
Drs. Fuyu Guan and Darko Stefanovski have started a schoolwide Artificial Intelligence Interest Group. If you are interested in joining the group, please contact Dr. Guan.
FEATURED ARTICLE
Dr. Wojciech Panek: A Passion for Pigeons Led to a Career in Neuro-Oncology and Neuro-Aging
Wojciech K. Panek, DVM, DACVIM (Neurology), is an assistant professor of neurology and neurosurgery in Penn Vet’s Department of Clinical Sciences and Advanced Medicine (CSAM). Dr. Panek knew he wanted to be a veterinarian quite early in his life, but the path to neurosurgery and a career as a clinician-scientist with a primary focus on neuro-oncology and neuro-aging was something he never anticipated.
Dr. Panek became a veterinarian because of pigeon racing. In the neighborhood in Poland where he grew up, almost everyone bred and raced pigeons. At this time, there were virtually no veterinarians in Poland who knew how to manage racing pigeon health, and the community of racing pigeon breeders struggled with the lack of specialists in this area. Therefore, Dr. Panek decided that he would become a racing pigeon veterinarian to fulfill this need. His first mentor, Professor Andrzej Dubiel, wrote the only book available in Poland about pigeon diseases. Dr. Panek read the book many times and decided to go to the school where Prof. Dubiel was a faculty member. He very quickly became a part of his student scientific association, where he worked and published pigeon-related scientific projects. This is how Dr. Panek’s skills and passion for science grew. Dr. Panek received his DVM degree from Wroclaw University of Environmental and Life Sciences in 2013. While continuing his research work, Dr. Panek went on to complete a rotating and surgical internship, during which he was encouraged by his new mentor, Dr. Niedzielski, to pursue further training in neurosurgery abroad.
In 2016, Dr. Panek was accepted for a post-doctoral scholarship at one of the top NIH-funded research programs in neuro-oncology at Northwestern University’s Feinberg School of Medicine, under the guidance of the internationally renowned researcher and neurosurgeon Dr. Maciej S. Lesniak. During this time, he studied the basic mechanisms of brain cancer initiation, growth, and spread, with a focus on developing translational therapies and conducting clinical trials. Dr. Panek pursued research projects focused on gene therapy, immunotherapy, stem cell-based therapy, and nanotechnology applications for brain cancer. In collaboration with others, he has developed novel oncolytic viral vectors and studied the relationship between glioma immunology and virotherapy. His work on CCL2, CCL22, and CD40L in a murine glioma model demonstrated its importance in crosstalk between immunosuppressive regulatory T cells and tumor cells. In addition, he performed a variety of novel microsurgical studies focusing on improving delivery methods of antineoplastic treatments for efficacious control of glioma in rodent models, which made him aware of unintended difficulties generated by the blood-brain barrier preventing transport of effective anti-cancer therapies to the brain. In addition, he mentored post-doctoral scholars and undergraduate students on a broad range of animal microsurgery techniques in neuroscience and established a murine model of breast cancer brain metastases (BCBM) via intracarotid artery infusion. The establishment of this model was critical to performing in vivo experiments as a part of an NIH-funded SPORE grant for Translational Approaches to Brain Cancer (P50CA221747). This work was published in Science Translational Medicine1.
In 2018, Dr. Panek was accepted for a post-doctoral scholarship at North Carolina State University College of Veterinary Medicine (NC State) in the laboratory of internationally renowned veterinary neurologist and neurosurgeon Dr. Natasha J. Olby. Under her mentorship, he developed and led a longitudinal clinical study on the brain aging of companion dogs and was a part of a phase I clinical trial on the safety and efficacy of a novel gene-silencing treatment for canine degenerative myelopathy. He actively collaborated with scientists and clinicians at NC State and Duke University to effectively design the study and to pursue novel discoveries. His highly collaborative efforts resulted in several peer-reviewed publications (Journal of Alzheimer’s Disease2, Molecular Neurobiology3-5) as well as the ‘Best Scientific Abstract Award’ at the 32nd ECVN/ESVN Annual Symposium. These opportunities allowed him to develop a strong skill set in translational research through a combination of clinical and benchtop work.
In 2020, Dr. Panek was accepted to a neurology and neurosurgery residency program at the University of California, Davis (UC Davis). Thanks to his mentors (Drs. Peter Dickinson, Beverly Sturges, Karen Vernau, Marguerite Knipe, Christine Toedebusch, and Chai-Fei Li), he remained engaged in basic and clinical brain tumor research. He successfully secured a Dr. Terrell A. Holliday Grant Award from the American College of Veterinary Internal Medicine (ACVIM) and Center for Companion Animal Health (CCAH) at UC Davis for the proposal entitled, The Role of CCL2/CCR4 Axis in Regulatory T Cell Trafficking to Canine Glioma—A Novel Therapeutic Target in Dogs. Dr. Panek graduated from UC Davis and successfully achieved board certification from the American College of Veterinary Internal Medicine, Specialty of Neurology (ACVIM, Neurology) in July 2023. Shortly after achieving board certification, he joined Penn Vet as an assistant professor of small animal neurology and neurosurgery.
Dr. Panek is excited to be part of CSAM, Ryan Hospital, and the Penn Vet Cancer Center. He is passionate about advancing the care of canine patients with glioma, a type of devastating primary brain cancer with a grave prognosis that affects both canine and human patients at similar rates. His studies focus on uncovering pathways in the pathogenesis of these tumors to ultimately design rational therapies based on hypothesis-driven research. Part of his work is also dedicated to patients with canine cognitive dysfunction, the analog of Alzheimer’s disease in humans. This aspect of his research focuses on the discovery of novel translational biomarkers for early detection of dementia, which may lead to effective therapeutic interventions or new therapies.
Dr. Panek hopes to create a translational neuroscience program by fostering collaborations with intramural and extramural research groups to benefit canine and human patients. He is currently working on several novel strategies aimed at reprogramming immune system responses in glioma and canine cognitive dysfunction patients to fight against and prevent the progression of these devastating diseases.
Selected References:
Panek WK, Khan OF, Yu D, and Lesniak MS. Multiplexed nanomedicine for brain tumors: nanosized Hercules to tame our Lernaean Hydra inside? Nanomedicine (Lond) 2017;12:2435-2439. https://www.tandfonline.com/doi/full/10.2217/nnm-2017-0260
Kanojia D, Panek WK, Cordero A, Fares J, Xiao A, Savchuk S, Kumar K, Xiao T, Pituch KC, Miska J, Zhang P, Kam KL, Horbinski C, Balyasnikova IV, Ahmed AU, and Lesniak MS. BET inhibition increases βIII-tubulin expression and sensitizes metastatic breast cancer in the brain to vinorelbine. Sci Transl Med 2020;12. https://www.science.org/doi/10.1126/scitranslmed.aax2879
Fefer G, Panek WK, Khan MZ, Singer M, Westermeyer HD, Mowat FM, Murdoch DM, Case B, Olby NJ, and Gruen ME. Use of cognitive testing, questionnaires, and plasma biomarkers to quantify cognitive impairment in an aging pet dog population. J Alzheimers Dis 2022;87:1367-1378. https://journals.sagepub.com/doi/abs/10.3233/JAD-215562
Panek WK, Pituch KC, Miska J, Kim JW, Rashidi A, Kanojia D, Lopez-Rosas A, Han Y, Yu D, Chang CL, Kane JR, Zhang P, Cordero A, and Lesniak MS. Local application of autologous platelet-rich fibrin patch (PRF-P) suppresses regulatory T cell recruitment in a murine glioma model. Mol Neurobiol 2019;56:5032-5040. https://doi.org/10.1007/s12035-018-1430-0
Panek WK, Gruen ME, Murdoch DM, Marek RD, Stachel AF, Mowat FM, Saker KE, and Olby NJ. Plasma neurofilament light chain as a translational biomarker of aging and neurodegeneration in dogs. Mol Neurobiol 2020;57:3143-3149. https://doi.org/10.1007/s12035-020-01951-0
Panek WK, Murdoch DM, Gruen ME, Mowat FM, Marek RD, and Olby NJ. Plasma amyloid beta concentrations in aged and cognitively impaired pet dogs. Mol Neurobiol 2021;58:483-489. https://doi.org/10.1007/s12035-020-02140-9
Latest Research
Highlighted News
Penn Vet Announces mRNA Research Initiative to Advance Veterinary Vaccine Science
The University of Pennsylvania (Penn) School of Veterinary Medicine (Penn Vet) announced the launch of the School’s mRNA Research Initiative to fast-track the development of veterinary mRNA-based vaccines and host-directed…
Understanding chronic wasting disease in deer (link is external)
A new collaborative study with Penn Vet researchers analyzed fecal samples to shed light on how the fatal disease impacts the gut microbiome in deer, providing a promising tool for…
Researchers breathe new life into lung repair (link is external)
A collaborative effort from teams across Penn culminates in new techniques to repair lung tissue after damage from flu and COVID-19.
Using fMRI, new vision study finds promising model for restoring cone function (link is external)
School of Veterinary Medicine and Perelman School of Medicine researchers identified a retinal disease to evaluate the success of gene and cell replacement therapy.
Scientists at the University of Pennsylvania’s School of Veterinary Medicine Shed New Light on the Evolution of Adaptive Immunity in Cold-Blooded Vertebrates
[December 1, 2023; Philadelphia, PA] – Upon infection or immunization, all jawed vertebrate species generate proteins called antibodies that bind and neutralize pathogens. Strong and long-lasting antibody responses in warm-blooded…
Inclusive, Ambitious Research to Meet the Needs of a Changing Planet
Projects from two groups led by Penn Vet faculty are supported by the University’s Environmental Innovations Initiative.
By the Numbers: Penn Vet’s agricultural impact (link is external)
In addition to excellence in teaching and clinical care for companion animals, Penn Vet makes indispensable contributions to the state’s agriculture sector.
Penn Vet’s Student Research Day was held on Friday, March 22, 2024, in the Vernon and Shirley Hill Pavilion. Dr. Elizabeth Woodward led the organizing committee, which included faculty members Drs. Elizabeth Lennon, Michael May, Jennifer Punt, and Phillip Scott; members of the Student Research Club Erin DeNardo and Samantha Lackeyram-Owen; VMD-PhD student Katherine Morucci; and staff member Kathy Kruger.
Dean Andrew Hoffman kicked off the day’s events with an introduction on the topic of “AI vs. PI,” which was an exploration of artificial intelligence (AI) in research and the qualities that principal investigators possess that AI cannot replace. Seven students delivered oral presentations (Kayla M. Even, Sara Hernández Suárez, Shelby Monnin, Lindsay Dwyer, Philip Hicks, Emerson Hunter, and Antonina Kalkus), and 37 posters were presented. Catherine K. Brinkley, VMD, PhD, an alumna of Penn Vet’s VMD-PhD program and associate professor, Department of Human Ecology, University of California, Davis, delivered a fascinating keynote presentation entitled Planning One Health in Policy and Action.
Academic prizes were awarded for three poster presentations (Erin DeNardo, Julia Pascarella, and Tiffany C. Wu), and all seven student oral presentations. This year’s academic prizes for oral and poster presentations were named for Professor Emeritus Richard O. Davies. Faculty judges for the abstracts and posters included Drs. Charles-Antoine Assenmacher, Timour Baslan, Daniel P. Beiting, Leonardo Brito, Ali Nabavizadeh, Kyla Ortved, Wojciech K. Panek, Laurel E. Redding,and Carlo Siracusa.
Student Research Day presentations and photos are available for online viewing.
Michael J. Hogan, PhD, is an assistant professor in the Department of Pathobiology. The overarching goals of his research laboratory are to uncover the mechanisms by which T cells mediate protection from viral infections and to translate these lessons into the design of new and improved mRNA vaccines against various diseases. Previously, he received his PhD from Penn under the mentorship of Drs. Drew Weissman (recipient of the 2023 Nobel Prize in Medicine) and Jim Hoxie, where he developed vaccine candidates against Zika virus and HIV. More recently, he did his postdoctoral training at Children’s Hospital of Philadelphia in the lab of Dr. Ike Eisenlohr, where he learned the skills he is currently using to study cellular immunity to mRNA vaccines.
Nicole Marino, PhD, is an assistant professor in the Department of Pathobiology. She received her Bachelor of Arts from Rice University in Houston, Texas, with dual majors in biochemistry & cell biology and classical studies. She obtained her PhD in 2018 from Stanford University, where she studied Toxoplasma gondii pathogenesis in John Boothroyd’s laboratory. Her fascination with parasites and infectious disease led her to explore the ancient arms race between bacteria and their genetic parasites (phage) as a postdoctoral fellow in Joseph Bondy-Denomy’s lab at the University of California, San Francisco. Her lab currently investigates the molecular mechanisms that bacteria use to thwart or prevent phage infection and how phage overcome these defenses. Outside of the lab, Nicole enjoys tango dancing, cooking, live music, and comedy shows.
Joy Tomlinson, DVM, PhD, DACVIM (LAIM), is an assistant professor of large animal medicine in the Department of Clinical Studies—New Bolton Center. She received her veterinary degree from Cornell University College of Veterinary Medicine in 2010. After graduation, she completed a private practice internship at Chino Valley Equine Hospital, followed by a residency in large animal internal medicine at New Bolton Center, achieving board certification in large animal internal medicine in 2014. After her residency, she worked at Cornell University as a lecturer and senior research associate before returning to the University of Pennsylvania in her current role. Her research focuses on equine viral hepatitis, including the pathogens equine parvovirus-hepatitis (EqPV-H) and equine hepacivirus (EqHV). Her ongoing research plans include both a big-picture approach to mapping the transmission, epidemiology, and disease associations of both viruses, as well as a finer look at the role of the immune responses in liver injury and determinants of disease severity. Her work in this area was recently recognized by the American Association of Equine Practitioners (AAEP) as the recipient of the AAEP 2021 Research Award.
Honors & Achievements
Drs. Gustavo Aguirre and William Beltran Elected to the Académie Vétérinaire de France
On February 1, 2024, Gustavo D. Aguirre, VMD, PhD, and William A. Beltran, DVM, PhD, were inducted as members of the Académie Vétérinaire de France (AVF). The AVF provides guidance on scientific, technical, legal, historical, and ethical fields in which the skills of the veterinarian are employed, in particular those relating to animals, their diseases, their relations with humans and the environment, animal production, and veterinary public health. The AVF contributes to the dissemination of scientific progress and the improvement of techniques relating to veterinary activities.
Dr. Igor Brodsky Elected Fellow of the American Academy of Microbiology
Igor Brodsky, PhD, was elected a Fellow of the American Academy of Microbiology. Fellows are elected annually through a highly selective, peer-review process based on their records of scientific achievement and original contributions that have advanced microbiology. The Academy received 156 nominations for fellowship this year.
Dr. Rebecka Hess Awarded Honorary Membership to the European Society for Veterinary Endocrinology
Rebecka S. Hess, DVM, MSCE, was named an Honorary Member of the European Society of Veterinary Endocrinology (ESVE). This award recognizes individuals who have made exceptional contributions to veterinary endocrinology throughout their lifetimes.
Dr. Louise Moncla Receives Two Scialog Collaborative Innovation Awards
Louise H. Moncla, PhD, is the recipient of two 2023 Scialog Collaborative Innovation Awards through a joint awards program from the Research Corporation for Science Advancement (RCSA) and the U.S. Department of Agriculture (USDA). The awards program brings together cross-disciplinary “mitigating zoonotic threats research teams” to address diagnostic and public health components associated with emerging animal-borne infectious diseases.
Drs. Nicola Mason and Antonia Rotolo Have An Accomplishment Worth Repeating
The news of Nicola Mason, BVetMed, PhD, and Antonia Rotolo, MD, PhD, receiving the 2023 Sebastian Strong Discovery Science Award was first reported in the summer 2023 issue of the newsletter, but sometimes circumstances require revisiting an accomplishment. What are those circumstances? A photo with a giant check! Most of us never know the excitement of being presented with an oversized promissory note, but Drs. Mason and Rotolo, along with their collaborators, can now tell us what it’s like. Congratulations on the award and on joining the rarefied group of entertainingly oversized check recipients!
Dr. Julie Engiles Receives Lindback Award for Distinguished Teaching
Julie B. Engiles, VMD, DACVP, is a 2024 recipient of the Christian R. and Mary F. Lindback Foundation Award for Distinguished Teaching. The Lindback Award is given in recognition of distinguished teaching, which is defined as teaching that is intellectually demanding, unusually coherent, and permanent in its effect. The distinguished teacher has the capability of changing the way in which students view the subject they are studying. The distinguished teacher is accessible to students and open to new ideas but also expresses their own views with an articulate and informed understanding of an academic field. The distinguished teacher is fair, free from prejudice, and single-minded in the pursuit of truth.
Dr. Ellen Puré Profiled by the Cancer Research Institute for Women’s History Month
In honor of Women’s History Month, the Cancer Research Institute published a profile of Dr. Ellen Puré highlighting “Women Driving Scientific Breakthroughs.”
Clinical Sciences & Advanced Medicine Announces 2024 CARF Awardees
The Companion Animal Research Fund (CARF), an internal funding program that is administered by Penn Vet’s Department of Clinical Sciences & Advanced Medicine, is intended to support new and early-career investigators and to assist established investigators with shifts of research focus. CARF supports clinical, pre-clinical, or pedagogical studies in canine and feline medicine. Preliminary, exploratory, pilot, or hypothesis-generating studies that have the potential to serve as a foundation for future extramural funding are prioritized.
Congratulations to the 2024 CARF awardees:
Ana C. Castejón-González, DVM, PhD, DACVD: Caudal mandibular fracture in cats: Development of a location-specific absorbable plate.
Stephen D. Cole, MS, VMD and Elizabeth M. Lennon, DVM, PhD: Fecal microbiota transfer to eradicate gastrointestinal colonization of carbapenem-resistant enterobacterales in dogs.
Alexandra V. Crooks, VMD: Utility of novel biomarker galectin-3 and cardiac MRI in evaluation of Boxers with arrhythmogenic right ventricular cardiomyopathy.
Erin Gibson, DVM: Feasibility and perioperative outcomes regarding ultra-low dose indocyanine green for indirect cholangiography during laparoscopic cholecystectomy in dogs.
Jennifer Lenz, DVM: Pilot study of frunevetmab (Solensia) for palliative therapy of feline bone-invasive oral tumors.
Lauren R. Powell, PhD: An exploratory study of the social determinants of canine behavior.
Estefanía Benavides Accepted into MAF Veterinary Student Scholar Program
Estefanía Benavides, V’25, a dual-degree student who is also pursuing a Master of Science in Translational Research in the Perelman School of Medicine, was accepted into the Morris Animal Foundation (MAF) Veterinary Student Scholar Program (VSSP). The MAF VSSP provides veterinary students in good standing with a stipend of up to $5,500 to pursue a research project under the guidance of a mentor. Estefanía is being mentored by Molly Church, VMD, PhD, and Jorge I. Alvarez, PhD.
Select Publications and Grants
Read the latest scholarly publication and grant information from Penn Vet researchers.
Abreu AR, Stefanovski D, Patil SP, Siddharthan T, Chediak A, Wallace DM, and Punjabi NM. Neuromuscular electrical stimulation for obstructive sleep apnoea: comparing adherence to active and sham therapy. ERJ Open Res 2023;9. https://doi.org/10.1183/23120541.00474-2023
Aitken MR, Floriano DA, and Hopster K. Open Approach to the Transversus Abdominis Plane in Horses: A Cadaver Feasibility Study. Vet Sci 2024;11. https://www.mdpi.com/2306-7381/11/1/51
Akuma DC, Wodzanowski KA, Schwartz Wertman R, Exconde PM, Marrero VRV, Odunze CE, Grubaugh D, Shin S, Taabazuing C, and Brodsky IE. Catalytic activity and autoprocessing of murine caspase-11 mediate noncanonical inflammasome assembly in response to cytosolic LPS. eLife 2024;13. https://doi.org/10.7554/eLife.83725
Alvarez-Jarreta J, Amos B, Aurrecoechea C, Bah S, Barba M, Barreto A, Basenko EY, Belnap R, Blevins A, Böhme U, Brestelli J, Brown S, Callan D, Campbell LI, Christophides GK, Crouch K, Davison HR, DeBarry JD, Demko R, Doherty R, Duan Y, Dundore W, Dyer S, Falke D, Fischer S, Gajria B, Galdi D, Giraldo-Calderón GI, Harb OS, Harper E, Helb D, Howington C, Hu S, Humphrey J, Iodice J, Jones A, Judkins J, Kelly SA, Kissinger JC, Kittur N, Kwon DK, Lamoureux K, Li W, Lodha D, MacCallum RM, Maslen G, McDowell MA, Myers J, Nural MV, Roos DS, Rund SSC, Shanmugasundram A, Sitnik V, Spruill D, Starns D, Tomko SS, Wang H, Warrenfeltz S, Wieck R, Wilkinson PA, and Zheng J. VEuPathDB: the eukaryotic pathogen, vector and host bioinformatics resource center in 2023. Nucleic Acids Res 2024;52:D808-D816. https://academic.oup.com/nar/article/52/D1/D808/7416377
Amirhosseini MH, Yadav V, Serpell JA, Pettigrew P, and Kain P. An artificial intelligence approach to predicting personality types in dogs. Sci Rep 2024;14:2404. https://doi.org/10.1038/s41598-024-52920-9
Andrews C, Williams R, and Burneko M. Use of liposomal bupivacaine in dogs and cats undergoing gastrointestinal surgery is not associated with a higher rate of surgical site infections or multidrug-resistant infections. J Am Vet Med Assoc 2024;262:1-6. https://doi.org/10.2460/javma.23.08.0463
Araos J, Driessen B, Brandly J, Gorenberg E, Heerdt P, Bruhn A, Martin-Flores M, Adler A, and Hopster K. Optimization of lung ventilation and perfusion in anesthetized horses using a ventilation mode with flow-limited expiration. Am J Vet Res2024;85:1-8. https://doi.org/10.2460/ajvr.23.09.0200
Berlin N, Pfaff A, Rozanski EA, Chalifoux NV, Hess RS, Donnino MW, and Silverstein DC. Establishment of a reference interval for thiamine concentrations in healthy dogs and evaluation of the prevalence of absolute thiamine deficiency in critically ill dogs with and without sepsis using high-performance liquid chromatography. J Vet Emerg Crit Care 2024;34:49-56. https://onlinelibrary.wiley.com/doi/10.1111/vec.13341
Bradbury AM, Bagel J, Swain G, Miyadera K, Pesayco JP, Assenmacher CA, Brisson B, Hendricks I, Wang XH, Herbst Z, Pyne N, Odonnell P, Shelton GD, Gelb M, Hackett N, Szabolcs P, Vite CH, and Escolar M. Combination HSCT and intravenous AAV-mediated gene therapy in a canine model proves pivotal for translation of Krabbe disease therapy. Mol Ther 2024;32:44-58. https://doi.org/10.1016/j.ymthe.2023.11.014
Brown KA, Bender SJ, and Johnson AL. Clinical and histopathological features in horses with neuroaxonal degeneration: 100 cases (2017-2021). J Vet Intern Med 2024;38:431-439. https://onlinelibrary.wiley.com/doi/10.1111/jvim.16969
Cantu A, Gutierrez MC, Dong X, Leek C, Anguera M, and Lingappan K. Modulation of recovery from neonatal hyperoxic lung injury by sex as a biological variable. Redox Biol 2023;68. https://doi.org/10.1016/j.redox.2023.102933
Carlson CM, Thomas S, Keating MW, Soto P, Gibbs NM, Chang H, Wiepz JK, Austin AG, Schneider JR, Morales R, Johnson CJ, and Pedersen JA. Plants as vectors for environmental prion transmission. iScience 2023;26:108428. https://doi.org/10.1016/j.isci.2023.108428
Carlson JA, Shetye S, Sun M, Weiss SN, Birk DE, and Soslowsky LJ. Collagen V haploinsufficiency in female murine patellar tendons results in altered matrix engagement and cellular density, demonstrating decreased healing. J Orthop Res 2023. https://onlinelibrary.wiley.com/doi/10.1002/jor.25740
Castejón-González AC, and Reiter AM. Surgical treatment for cleft palate in dogs yields excellent outcomes despite high rates of oronasal fistula formation: a narrative review. J Am Vet Med Assoc 2023;261:S34-S43. https://doi.org/10.2460/javma.23.06.0330
Castejón-González AC, and Reiter AM. Use of a barrier membrane to repair congenital hard palate defects and to close oronasal fistulae remaining after cleft palate repair: seven dogs (2019-2022). J Am Vet Med Assoc 2024;262:1-10. https://doi.org/10.2460/javma.23.07.0393
Chen T, Wang Q, Wang Y, Dou Z, Yu X, Feng H, Wang M, Zhang Y, and Yin J. Using fresh vegetable waste from Chinese traditional wet markets as animal feed: Material feasibility and utilization potential. Sci Total Environ 2023;902:166105. https://doi.org/10.1016/j.scitotenv.2023.166105
Ciamillo SA, Wulster KB, Gassert TM, Richardson DW, Brown KA, Stefanovski D, and Ortved KF. Prospective, longitudinal assessment of subchondral bone morphology and pathology using standing, cone-beam computed tomography in fetlock joints of 2-year-old Thoroughbred racehorses in their first year of training. Equine Vet J 2024. https://beva.onlinelibrary.wiley.com/doi/10.1111/evj.14048
Cole SD, Dietrich J, and Rankin SC. Use of a chromogenic medium with and without selective enrichment to screen for carbapenemase-producing Enterobacterales (CPE) from canine and feline fecal specimens during an outbreak of NDM-5–producing Escherichia coli. J Vet Diagn Invest 2024;36:124-127. https://journals.sagepub.com/doi/10.1177/10406387231204560
Convey V, Huh T, Achilles EJ, Massey LK, McKaba VF, Loughran KA, Kraus MS, Gelzer AR, Crooks AV, and Oyama MA. Urine sodium concentration after intravenous furosemide in dogs with acute congestive heart failure and correlation with treatment efficacy. J Vet Intern Med 2024;38:71-80. https://onlinelibrary.wiley.com/doi/10.1111/jvim.16955
Cortellini S, DeClue AE, Giunti M, Goggs R, Hopper K, Menard JM, Rabelo RC, Rozanski EA, Sharp CR, Silverstein DC, Sinnott-Stutzman V, and Stanzani G. Defining sepsis in small animals. J Vet Emerg Crit Care 2024. https://onlinelibrary.wiley.com/doi/10.1111/vec.13359
Crofts JL, Radtke B, Chalifoux NV, and Reineke EL. Increased incidence and shift in the location of gunshot wound injuries in dogs and cats during the COVID-19 pandemic. J Am Vet Med Assoc 2023;261:1862-1866. https://doi.org/10.2460/javma.23.06.0317
Danan CH, Naughton KE, Hayer KE, Vellappan S, McMillan EA, Zhou Y, Matsuda R, Nettleford SK, Katada K, Parham LR, Ma X, Chowdhury A, Wilkins BJ, Shah P, Weitzman MD, and Hamilton KE. Intestinal transit-amplifying cells require METTL3 for growth factor signaling and cell survival. JCI Insight 2023;8. https://doi.org/10.1172/jci.insight.171657
Didier A, Bourner M, Kleks G, Zolty A, Kumar B, Nichols T, Durynski K, Bender S, Gibison M, Murphy L, Ellis JC, Dong DW,and Kashina A. Prospective fecal microbiomic biomarkers for chronic wasting disease. Microbiol Spectr 2024;12:e03750-22. https://journals.asm.org/doi/10.1128/spectrum.03750-22
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Michael Atchison
Boehringer Ingelheim Vetmedical
2024 BI Veterinary Summer Scholars Program
1/1/24—12/31/24
30,800
Michael Atchison
NIH
Short-term training: Students in health professional schools
4/1/24—3/31/25
126,776
Matthew Atherton
Penn Vet Cancer Center
PVCC pilot
1/1/24—12/31/25
75,000
Matthew Atherton
AKC Canine Health Foundation
A blueprint to develop next generation CAR T therapy for canine lymphoma
2/1/24—1/31/26
162,000
Estefanía Benavides (Church Lab)
Morris Animal Foundation
Determining neurodegenerative and neuroinflammatory biomarkers in canine meningoencephalitides of unknown origin
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5,500
Serge Fuchs
NIH
Targeting immunosuppression of intratumoral CAR T cells
2/01/24—1/31/29
364,371
De’Broski Herbert
Burroughs Wellcome Fund
27th Annual Woods Hole Immunoparasitology (WHIP) Meeting
2/01/24—6/30/24
5,000
Christopher Hunter
Incyte
Investigate the functional and molecular effect of IL-15 blockade on NK and T cell responses during chronic infection
12/22/23—12/21/24
103,645
Mary Lassaline
ACVO Vision for Animals Foundation
Comparison of needle electrodes versus gold cup skin electrodes for scotopic clinical electroretinography in the dog
2/15/24—2/14/26
3,500
Nicole Marino
NIH
Discovery of novel phage-bacterial interactions
1/04/24—12/31/26
459,693
Louise Moncla
NIH
NIAID Centers of Excellence for Influenza Research and Response
9/18/23—9/17/25
109,748
Louise Moncla
Department of Agriculture
When pigs fly: Animal movement networks to project spillovers
1/1/24—12/31/24
50,000
Louise Moncla
Department of Agriculture
To catch a virus: Decoy polymers and influenza’s evolutionary response
1/1/24—12/31/24
50,000
Lisa Murphy
CPLE
Training funds for veterinary workforce development to benefit animal agriculture
11/1/2023—11/21/2024
38,600
Cynthia Otto
AKC Canine Health Foundation
Investigating volatile organic compounds as potential markers of canine hemangiosarcoma by trained bio-detection dogs
2/1/24—1/31/26
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Cynthia Otto
Waltham Foundation
Body condition scoring in dogs: Understanding barriers to owners receiving information and improving dog health
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31,643
Cynthia Otto
Commonwealth of Pennsylvania
PEMA FY24 Penn Vet Working Dog Center
7/1/2023—6/30/2024
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Kotaro Sasaki
Open Philanthropy Project
Establishment of primate germline stem cells using pluripotent stem cell-derived spermatogonia
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University of Texas Southwestern Medical Center
Elucidating the effects of extra chromosome elimination in aneuploidy syndromes: Pallister-Killian syndrome as a model
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17,564
P. Jeremy Wang
NIH
Molecular mechanism and regulation of meiosis
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357,410