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Dr. De'Broski Herbert's research on parasitic worms and the dual nature of a key immune regulator.

Follow the Worm - the dual nature of a key immune regulator

Using a naturally occurring species of mouse Cryptosporidium, a team led by researchers from Penn’s School of Veterinary Medicine has developed a model of infection that affects immunologically normal mice.

Novel Model for Studying Intestinal Parasite

A disease in dogs opens new avenues for study

Pinpointing how cancer cells turn aggressive

Research has found a way to block the Marburg virus from spreading.

Blocking viruses’ exit strategy

Vite Lab and the Krabbe team members celebrate a breakthrough in their research

Towards a Treatment for Krabbe Disease

A leaky blood-brain barrier and schizophrenia

Cytokine Storms

Turning back the clock on a severe vision disorder

Household Food Insecurity and the COVID-19 Pandemic

Stopping Cancer’s Spread

Coming Together to Solve the Mysteries of COVID-19

Gary Althouse (shown pre-pandemic) notes that the animal origins of the current Covid-19 crisis underscore the importance of veterinary expertise in sustaining both animal and human health.

Supporting Agriculture and a Safe Food Supply

Tailoring Treatment for Triple-negative Breast Cancer

Wang and colleagues have identified an enzyme that plays a crucial role in maintaining this chromosomal pairing during the pachytene stage of meiosis.

Treating Male Infertility

J. Oriol Sunyer of Penn’s School of Veterinary Medicine has made transformational scientific insights using a very different creature: rainbow trout.

Mysteries in the Gills of Rainbow Trout

Toxoplasma gondii parasites inject their host’s macrophages, a type of immune cell, with a protein that changes the activity of the macrophage itself, creating what is known as an M2 macrophage.

Towards a More Effective Immune Response

Dr. Zhengxia Dou, Professor of Agricultural Systems, Penn Vet

Pioneering Sustainable Food Systems

A new study reveals that the protein deltaNp63, which fosters the initiation and progression of triple-negative breast cancer, also helps fuel mammary gland development during puberty in mice.

A New Role for Protein deltaNp63 in Breast Cancer

Mary Robinson, director of Penn Vet’s Equine Pharmacology Laboratory

Keeping the Sport Safe

Drs. William Beltran, Susan Volk, and Gustavo Aguirre were recognized for research on suppressing breast cancer recurrence and therapies for the treatment of inherited retinal disorders.

Inventors of the Year

Researchers Ronald Harty and Bruce Freedman use a variety of laboratory tests to screen compounds that might block budding and slow down the spread of the Ebola.

Making Headway Against a Killer Virus

Predicting treatment outcome for leishmaniasis

The risk of zoonotic diseases is becoming more and more real.

Animals to People and Back Again

Dr. Christopher A. Hunter to lead International Cytokine and Interferon Society

Dr. James Serpell talks about how dog breed can affect behavior.

Genes play a role in dog breed differences in behavior

Dr. Keiko Miyadera and a team of researchers have identified a gene for canine blindness.

Identifying a Gene for Canine Blindness

An FDA-approved gene therapy for Leber congenital amaurosis, an inherited vision disorder with a childhood onset and progressive nature, has improved patients’ sight.

Treatment for Retinal Blindess Depends on Timing

The Diet-Microbiome Connection in IBD

Dr. Andrew Vaughan and his team found that transplanting a certain type of lung cell from healthy mice to those that had been injured by an infection with influenza could improve healing.

Lung Cell Transplant Boosts Healing

Pennsylvania Wildlife Futures Program

Parasites, Mosquito Guts, and Disease Transmission

Auroraceratops, a small-bodied plant-eater, is now one of the few very early horned dinosaurs known from complete skeletons. This dinosaur lived roughly 115 million years ago.

Meet Dawn's Horned Face - Auroraceratops

Working under the supervision of Penn scientists Jennifer Punt and John Wagner, these students are doing more than just honing their scientific technique; they’re advancing the field of canine immunology.

Meaningful Science With Students at the Helm

Peaches, a shelter dog benefiting from the Penn Vet Shelter Canine Mammary Tumor Program.

Better Prognosticating for Dogs With Mammary Tumors

Center for Host-Microbial Interactions, Penn Vet

Demystifying Genomic Technology

Mitochondrial damage is linked to the bone degradation seen in osteoporosis

Mitochondrial Damage and Osteoporosis

A Fascination for Nematodes

In the Office with Dr. Zhengxia Dou

Unlocking the Female Bias in Lupus

New Bolton Center's Dr. Joseph Bender, Center for Animal Health & Productivity

Helping Farms Flourish in Tough Times

In a mouse model, the FDA-approved drug resperine seemed to hamper the ability of tumors to reshape distant tissues in ways that would encourage metastasis.

Hindering Melanoma Metastasis

A single injection of gene therapy containing a normal version of the LRIT3 gene resulted in lasting restoration of night vision in dogs affected by a form of congenital stationary night blindness similar to one affecting humans.

Correcting night blindness in dogs

Bijels, or bicontinuous interfacially jammed emulsion gels, are structured emulsions of oil and water that are kept separated by a layer of nanoparticles.

From a pandemic, scientific insights poised to impact more than just COVID-19

A report led by Penn Vet's Dr. Elizabeth Lennon and colleagues has confirmed what is believed to be the first published account of the delta variant of SARS-CoV-2 in a house cat.

COVID in a Cat

Dr. Jeremy Wang and his team's work in fertility

Fertility Insights

Dr. Andrés Blanco studies cancer cells and how to change their 'identity'

Changing the Identity of Cancer Cells to Eliminate Them

A new drug target for chemically induced Parkinson’s disease

How Chemical Insults Lead to Parkinson’s Disease

The Penn Vet Comparative Pathology Core provides expert pathological characterization and validation of mouse and other animal models.

Learn About the Penn Vet Comparative Pathology Core

Isolating extracellular vesicles

Research

The primary focus of the research at Penn Vet is to understand diseases of animals to improve animal health, and to provide translational knowledge to advance human health.

Our faculty are leaders in their areas of specialty, and have made significant contributions through their research to global health. Several of our faculty are dually appointed with Penn Medicine, as well as other schools and programs at the University of Pennsylvania. Many work collaboratively with other institutions here in the United States and throughout the world.

Explore this section and learn about the groundbreaking research taking place at Penn Vet that affects animals and humans alike.