The protein actin is ubiquitous and essential for life. In mammals, every cell expresses two of its forms, beta-actin and gamma-nonmuscle-actin. Despite having distinct roles, the two forms are nearly…
The canine disease granulomatous meningoencephalomyelitis (GME), the most common neuroinflammatory disease that affects dogs, shares key features of its pathology and immunology with multiple sclerosis (MS), according to a new…
Penn scientists have developed a new method for tracing the lineage and gene expression patterns of metastatic cancer at the single-cell level.
The Marburg virus, a relative of the Ebola virus, causes a serious, often-fatal hemorrhagic fever. Transmitted by the African fruit bat and by direct human-to-human contact, Marburg virus disease currently…
Timothy Manzi was the son of horse people. His father raced horses for a living, and his mother also worked with horses. “It was a little like second nature to me,”…
The blood-brain barrier keeps out anything that could lead to disease and dangerous inflammation—at least when all is functioning normally.
Many long for a return to a post-pandemic “normal,” which, for some, may entail concerts, travel, and large gatherings. But how to keep safe amid these potential public health risks?
Gustavo Aguirre and William Beltran, veterinary ophthalmologists and vision scientists at the University of Pennsylvania School of Veterinary Medicine, have studied a wide range of different retinal blinding disorders. But the one caused by…
Last month, it was gorillas. Before that, it was mink. And earlier still, tigers and lions. All of these species have been confirmed to have had a diagnosis of COVID-19,…
In today’s climate change narrative, animal-based agriculture often endures criticism for its alleged contributions to the global problem. With some naysayers ranking the industry second only to the population explosion…