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    Penn Today

    Harnessing an innate protection against Ebola

    In their evolutionary battle for survival, viruses have developed strategies to spark and perpetuate infection. Once inside a host cell, the Ebola virus, for example, hijacks molecular pathways to replicate…

    How sex differences may influence lung injury

    Comparing lung cells from male and female mice, Penn Vet scientists found gene expression differences that may explain why older males are at a higher risk than females for worse…

    NIH-funded canine immunotherapy data center charts a path toward transformative therapies

    With support recently for five more years, Nicola Mason of the School of Veterinary Medicine and Qi Long of the Perelman School of Medicine hope their work leads to new…

    Progress toward a stem cell–based therapy for blindness

    A multi-institutional effort led by researchers at Penn Vet is taking steps to develop an effective technique to regenerate photoreceptors cells and restore sight in people with vision disorders.

    A newly identified stem cell regulator enables lifelong sperm production

    Research led by Dr. Jeremy Wang has discovered that the enzyme DOT1L, a stem cell renewal factor, is essential for mice to produce sperm throughout their adult lives.

    Frozen testicular tissue still viable after 20 years

    A new study in rats has shown that male testis tissue that is cryopreserved can be reimplanted after more than 20 years and will go on to make viable sperm.

    From a pandemic, scientific insights poised to impact more than just COVID-19

    Pivoting to study SARS-CoV-2, many scientists on campus have launched new research projects that address the challenges of the pandemic but also prepare us to confront future challenges.

    COVID in a cat

    A report led by Penn Vet’s Dr. Elizabeth Lennon and colleagues has confirmed what is believed to be the first published account of the delta variant of SARS-CoV-2 in a house…

    Revealing the mysterious biology of a fundamental process: reproduction

    New findings from the lab of Dr. P. Jeremy Wang shed light on the cell division process that creates eggs and sperm, recurrent pregnancy loss, and the mechanism by which…

    Pinpointing how cancer cells turn aggressive

    Penn scientists have developed a new method for tracing the lineage and gene expression patterns of metastatic cancer at the single-cell level.

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