News Articles

    Removing the barrier surrounding solid tumors clears path for T cells

    Penn researchers uncover a new way to target solid tumors. Using CAR T cells to remove cancer-associated fibroblasts surrounding pancreatic tumors allows T cells to infiltrate and attack the tumor…

    Genetic switch turns tumor suppressor into oncogene in colorectal cancer

    Researchers from the School of Veterinary Medicine have shown that an enzyme that suppresses early-stage colorectal cancer switches to become an oncogene as the cancer progresses.

    Dipti Pitta with a cow.

    Could we breed cows that emit less methane?

    In a new study, researchers from the School of Veterinary Medicine identified attributes of low-methane-emitting dairy cows that could be used as targets for selective breeding.

    Harnessing an innate protection against Ebola

    In their evolutionary battle for survival, viruses have developed strategies to spark and perpetuate infection. Once inside a host cell, the Ebola virus, for example, hijacks molecular pathways to replicate…

    How sex differences may influence lung injury

    Comparing lung cells from male and female mice, Penn Vet scientists found gene expression differences that may explain why older males are at a higher risk than females for worse…

    NIH-funded canine immunotherapy data center charts a path toward transformative therapies

    With support recently for five more years, Nicola Mason of the School of Veterinary Medicine and Qi Long of the Perelman School of Medicine hope their work leads to new…

    Progress toward a stem cell–based therapy for blindness

    A multi-institutional effort led by researchers at Penn Vet is taking steps to develop an effective technique to regenerate photoreceptors cells and restore sight in people with vision disorders.

    A newly identified stem cell regulator enables lifelong sperm production

    Research led by Dr. Jeremy Wang has discovered that the enzyme DOT1L, a stem cell renewal factor, is essential for mice to produce sperm throughout their adult lives.

    Frozen testicular tissue still viable after 20 years

    A new study in rats has shown that male testis tissue that is cryopreserved can be reimplanted after more than 20 years and will go on to make viable sperm.

    Regulating the regulators of the immune system

    Research led by Penn Vet scientists reveals a new layer of complexity with which the immune system finds a balance between controlling pathogens and protecting healthy tissue.

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