New Bolton Center Kennett Square, PA
Emergencies & Appointments:
Ryan Hospital Philadelphia, PA



Associate Professor of Laboratory Animal Medicine, University of Pennsylvania School of Veterinary Medicine

Clinical Specialties: Outbreak management, Immune-deficient murine models,
PubMed Link
Contact Information:
3800 Spruce Street, OVQ 177E

Clinical interests include outbreak management in immune-deficient murine models, specifically containment and eradication of bacterial infections that threaten research model integrity. I also focus on model refinement and translational medicine models.

Miedel, E. L., Ragland, N. H., Slate, A. R., Engelman, R. W. Persistent Corynebacterium bovis infectious hyperkeratotic dermatitis in immunocompetent epidermal-mutant dep/dep mice Veterinary Pathology 57: 586-589, 2020.

Ragland, N. H., Miedel, E. L., Engelman, R. W. PCR prevalence of murine opportunistic microbes and their mitigation by using vaporized hydrogen peroxide J Am Assoc Lab Anim Sci 58: 208-215, 2019.

Rodriguez, I., Philips, B. H., Miedel, E. L., Bright, L. A., LaTourette Ii, P. C., Carty, A. J., Witschey, W. R., Gorman, R. C., Gorman Iii, J. H., Marx, J. O. Hydromorphone-induced neurostimulation in a Yorkshire swine (Sus scrofa) after myocardial infarction surgery J Am Assoc Lab Anim Sci 58: 601-605, 2019.

Wallace, C. K., Bell, S. E., LaTourette, P. C., 2nd, Miedel, E. M., Carty, A. J., Philips, B. H. Suspected Anaphylactic Reaction to Ketamine in 3 Yucatan Swine (Sus scrofa) Comparative Medicine 69: 419-424, 2019.

Vedder, A. R., Miedel, E. L., Ragland, N. H., Balasis, M. E., Letson, C. T., Engelman, R. W., Padron, E. Effects of Corynebacterium bovis on engraftment of patient-derived chronic-myelomonocytic leukemia cells in NSGS mice Comparative Medicine 69: 276-282, 2019.

Misic, A. M., Miedel, E. L., Brice, A. K., Cole, S., Zhang, G. F., Dyer, C. D., Secreto, A., Smith, A. L., Danet-Desnoyers, G., Beiting, D. P. Culture-independent profiling of the fecal microbiome to identify microbial species associated with a diarrheal outbreak in immunocompromised mice Comparative Medicine 68: 261-268, 2018.

Miedel, E. L., Ragland, N. H., Engelman, R. W. Facility-wide eradication of Corynebacterium bovis by using PCR-validated vaporized hydrogen peroxide J Am Assoc Lab Anim Sci 57: 465-476, 2018.

Ragland, N. H., Miedel, E. L., Gomez, J. M., Engelman, R. W. Staphylococcus xylosus PCR-validated decontamination of murine individually ventilated cage racks and air handling units by using ''active-closed'' exposure to vaporized hydrogen peroxide J Am Assoc Lab Anim Sci 56: 742-751, 2017.

Miedel, Emily L., Hankenson, F. Claire Biology and Diseases of Hamsters [Chapter 5] Laboratory Animal Medicine : 209-245, 2015.

Miedel, E. L., Brisson, B. K., Hamilton, T., Gleason, H., Swain, G. P., Lopas, L., Dopkin, D., Perosky, J. E., Kozloff, K. M., Hankenson, K. D., Volk, S. W. Type III collagen modulates fracture callus bone formation and early remodeling Journal of Orthopaedic Research 33: 675-84, 2015.

Miedel, E., Dishowitz, M. I., Myers, M. H., Dopkin, D., Yu, Y. Y., Miclau, T. S., Marcucio, R., Ahn, J., Hankenson, K. D. Disruption of thrombospondin-2 accelerates ischemic fracture healing Journal of Orthopaedic Research 31: 935-43, 2013.

Burke, D., Dishowitz, M., Sweetwyne, M., Miedel, E., Hankenson, K. D., Kelly, D. J. The role of oxygen as a regulator of stem cell fate during fracture repair in TSP2-null mice Journal of Orthopaedic Research 31: 1585-96, 2013.

Baran, S. W., Perret-Gentil, M. I., Johnson, E. J., Miedel, E. L., Kehler, J. Rodent laparoscopy: refinement for rodent drug studies and model development, and monitoring of neoplastic, inflammatory and metabolic diseases Laboratory Animals 45: 231-9, 2011.

B.S. (Business and Economics) La Salle University, 2000

V.M.D. (Veterinary Medicine) University of Pennsylvania, 2007


University of Pennsylvania (2009 to 2012)
Residency, Laboratory Animal Medicine