Fuyu Guan, PhD
Fuyu Guan, PhD, is Research Professor of Equine Forensic Chemistry at the University of Pennsylvania School of Veterinary Medicine. Dr. Guan has been recognized nationally and internationally for his work on establishing novel analytical methodologies for the detection and confirmation of peptide- and protein-based drugs for drug testing in horse racing, as well as novel approach to comprehensive untargeted detection of emerging doping agents in post-competition racehorse blood samples. Dr. Guan’s research interests are focused on developing new analytical methods to address challenging issues in equine drug testing to protect the integrity of horse racing, and the application of artificial intelligence in equine drug testing.
Fuyu Guan, Savannah Fay, Matthew A Adreance, Leif K McGoldrick, Rachel M Proctor, Jaclyn R Missanelli, Youwen You, and Mary A Robinson Automated identification of unknown doping agents in confiscation samples by flow-injection mass spectrometry and mass spectral library searches Drug Detection and Analysis 15: 779-786, 2023.
Fuyu Guan, Youwen You, Savannah Fay, Matthew A Adreance, Leif K McGoldrick, and Mary A Robinson Factors affecting untargeted detection of doping agents in biological samples Talanta 258: 124446, 2023.
Fuyu Guan, Youwen You, Savannah Fay, Xiaoqing Li, and Mary A. Robinson Novel Algorithms for Comprehensive Untargeted Detection of Doping Agents in Biological Samples Analytical Chemistry 93: 7746-7753, 2021.
Fuyu Guan, Savannah Fay, Xiaoqing Li, Youwen You, Mary A. Robinson Identification of exvivo catabolites of peptides with doping potential in equine plasma by HILIC-HRMS. Drug Testing and Analysis Volume 12: 771-784, 2020.
Fuyu Guan, Youwen You,Xiaoqing Li, Mary A. Robinson A comprehensive approach to detecting multitudinous bioactive peptides in equine plasma and urine using hydrophilic interaction liquid chromatography coupled to high resolution mass spectrometry. Drug Testing and Analysis 11: 1308-1325, 2019.
Guan F, You Y, Li X and Robinson MA Detection and confirmation of a-cobratoxin in equine plasma by solid-phase extraction and liquid chromatography coupled to mass spectrometry. Journal of Chromatography A 1533: 38-48, 2018.
Guan F and Robinson MA Comprehensive solid-phase extraction of multitudinous bioactive peptides from equine plasma and urine for doping detection. Analytica Chimica Acta 985: 79-90, 2017.
Guan F, Uboh CE, Soma LR, Robinson M, Maylin GA, Li X Detection, quantification and identification of dermorphin in equine plasma and urine by LC-MS/MS for doping control. Analytical and Bioanalytical Chemistry 405: 4707-4717, 2013.
Guan Fuyu, Uboh Cornelius E, Soma Lawrence R, You Youwen, Li Xiaoqing, McDonnell SueEx vivo spontaneous generation of 19-norandrostenedione and nandrolone detected in equine plasma and urine. The Journal of steroid biochemistry and molecular biology 128: 1-11, 2012.
Guan Fuyu, Uboh Cornelius E, Soma Lawrence R, Birks Eric, Chen Jinwen, You Youwen, Rudy Jeffrey, Li Xiaoqing Differentiation and identification of recombinant human erythropoietin and darbepoetin Alfa in equine plasma by LC-MS/MS for doping control. Analytical chemistry 80: 3811-7, 2008.
Guan Fuyu, Uboh Cornelius E, Soma Lawrence R, Birks Eric, Chen Jinwen, Mitchell Janis, You Youwen, Rudy Jeffrey, Xu Fran, Li Xiaoqing, Mbuy Gustave LC-MS/MS method for confirmation of recombinant human erythropoietin and darbepoetin alpha in equine plasma. Analytical chemistry 79: 4627-35, 2007.
Analytical chemistry; Drug detection; Forensic chemistry; Liquid chromatography; LC-MS; Mass spectrometry; Metabolomics; Proteomics; Peptides; Small molecule drugs
Hamamatsu University School of Medicine (1996 to 1998) Postdoctoral Fellow
Education:
PhD (Analytical Chemistry) Peking University, China, 1989 MSci (Analytical Chemistry) Peking University, 1986 BSci (Chemistry) Peking University, 1983
Contact:
University of Pennsylvania
School of Veterinary Medicine
3800 Spruce Street
Philadelphia, PA 19104