New Bolton Center Kennett Square, PA
Emergencies & Appointments:
Ryan Hospital Philadelphia, PA


Assistant Professor of Anatomic Pathology, Department of Pathobiology, University of Pennsylvania School of Veterinary Medicine

Research Areas: Diagnostic Pathology, Comparative pathogenesis of viral disease
PubMed Link
Contact Information:

Plunkard, J., Mulka, K., Zhou, R., Tarwater, P., Zhong, W., Lowman, M., Wong, A., Pekosz, A., Villano, J. SARS-CoV-2 Variant Pathogenesis Following Primary Infection and Reinfection in Syrian Hamsters mBio 14: e0007823, 2023.

Creisher, P. S., Perry, J. L., Zhong, W., Lei, J., Mulka, K. R., Ryan, H., Zhou, R., Akin, E. H., Liu, A., Mitzner, W., Burd, I., Pekosz, A., Klein, S. L. Adverse outcomes in SARS-CoV-2 infected pregnant mice are gestational age-dependent and resolve with antiviral treatment bioRxiv : , 2023.

Ruiz-Bedoya, C. A., Mota, F., Ordonez, A. A., Foss, C. A., Singh, A. K., Praharaj, M., Mahmud, F. J., Ghayoor, A., Flavahan, K., De Jesus, P., Bahr, M., Dhakal, S., Zhou, R., Solis, C. V., Mulka, K. R., Bishai, W. R., Pekosz, A., Mankowski, J. L., Villano, J., Klein, S. L., Jain, S. K. (124)I-Iodo-DPA-713 Positron Emission Tomography in a Hamster Model of SARS-CoV-2 Infection Molecular Imaging and Biology 24: 135-143, 2022.

Mulka, K. R., Beck, S. E., Solis, C. V., Johanson, A. L., Queen, S. E., McCarron, M. E., Richardson, M. R., Zhou, R., Marinho, P., Jedlicka, A., Guerrero-Martin, S., Shirk, E. N., Braxton, A. M., Brockhurst, J., Creisher, P. S., Dhakal, S., Brayton, C. F., Veenhuis, R. T., Metcalf Pate, K. A., Karakousis, P. C., Zahnow, C. A., Klein, S. L., Jain, S. K., Tarwater, P. M., Pekosz, A. S., Villano, J. S., Mankowski, J. L. Progression and resolution of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection in golden Syrian hamsters American Journal of Pathology 192: 195-207, 2022.

Jiang, L., Driedonks, T. A. P., Jong, W. S. P., Dhakal, S., Bart van den Berg van Saparoea, H., Sitaras, I., Zhou, R., Caputo, C., Littlefield, K., Lowman, M., Chen, M., Lima, G., Gololobova, O., Smith, B., Mahairaki, V., Riley Richardson, M., Mulka, K. R., Lane, A. P., Klein, S. L., Pekosz, A., Brayton, C., Mankowski, J. L., Luirink, J., Villano, J. S., Witwer, K. W. A bacterial extracellular vesicle-based intranasal vaccine against SARS-CoV-2 protects against disease and elicits neutralizing antibodies to wild-type and Delta variants J Extracell Vesicles 11: e12192, 2022.

Braxton, A. M., Creisher, P. S., Ruiz-Bedoya, C. A., Mulka, K. R., Dhakal, S., Ordonez, A. A., Beck, S. E., Jain, S. K., Villano, J. S. Hamsters as a model of Severe Acute Respiratory Syndrome Coronavirus-2 Comparative Medicine 71: 398-410, 2021.

Dhakal, S., Loube, J., Misplon, J. A., Lo, C. Y., Creisher, P. S., Mulka, K. R., Deshpande, S., Mitzner, W., Klein, S. L., Epstein, S. L. Effect of an adenovirus-vectored universal influenza virus vaccine on pulmonary pathophysiology in a mouse model Journal of Virology 95: , 2021.

Zhao, Z., Muth, D. C., Mulka, K., Liao, Z., Powell, B. H., Hancock, G. V., Metcalf Pate, K. A., Witwer, K. W. miRNA profiling of primate cervicovaginal lavage and extracellular vesicles reveals miR-186-5p as a potential antiretroviral factor in macrophages FEBS Open Bio 10: 2021-2039, 2020.

Vom Steeg, L. G., Dhakal, S., Woldetsadik, Y. A., Park, H. S., Mulka, K. R., Reilly, E. C., Topham, D. J., Klein, S. L. Androgen receptor signaling in the lungs mitigates inflammation and improves the outcome of influenza in mice PLoS Pathogens 16: e1008506, 2020.

Oei, A. L., Korangath, P., Mulka, K., Helenius, M., Coulter, J. B., Stewart, J., Velarde, E., Crezee, J., Simons, B., Stalpers, L. J. A., Kok, H. P., Gabrielson, K., Franken, N. A. P., Ivkov, R. Enhancing the abscopal effect of radiation and immune checkpoint inhibitor therapies with magnetic nanoparticle hyperthermia in a model of metastatic breast cancer International Journal of Hyperthermia 36: 47-63, 2019.

Collins, D. E., Mulka, K. R., Hoenerhoff, M. J., Taichman, R. S., Villano, J. S. Clinical assessment of urinary tract damage during sustained-release estrogen supplementation in mice Comparative Medicine 67: 11-21, 2017.