New Bolton Center Kennett Square, PA
Emergencies & Appointments:
Ryan Hospital Philadelphia, PA


American College of Veterinary Internal Medicine Specialty of Large Animal Internal Medicine

Professor Emeritus of Medicine, University of Pennsylvania School of Veterinary Medicine

Clinical Specialties: Large Animal Internal Medicine
Research Areas: Paratuberculosis (Johne's Disease), Pharmacokinetics of antimicrobial drugs, Botulism

Contact Information:
University of Pennsylvania
School of Veterinary Medicine
Dept of Clinical Studies
New Bolton Center
382 West Street Road

Paratuberculosis (Johne's Disease)
-Immune Response
-Experimental Infection Models

Pharmacokinetics of antimicrobial drugs

Large Animal Internal Medicine

Beaver, A, Sweeney, R.W., Hovingh, E., Wolfgang, D.R., Gröhn, Y.T., Schukken, Y.H. Longitudinal relationship between fecal culture, fecal quantitative PCR, and milk ELISA in Mycobacterium avium ssp. paratuberculosis-infected cows from low-prevalence dairy herds J Dairy Science 100: 7507, 2017.

Fecteau M-E, Pitta DW, Vecchiarellis B, Indugu N, Kumar S, Gallagher SC, Fyock TL, Sweeney RW Dysbiosis of the fecal microbiota in cattle infected with Mycobacterium avium subsp. paratuberculosis PLoS ONE 11: , 2016.

Sweeney RW, Whitlock RH, Bowersock TL, Cleary DL, Meinert TR, Habecker PL, Pruitt GW Effect of subcutaneous administration of a killed Mycobacterium avium subsp. paratuberculosis vaccine on colonization of tissues following oral exposure to the organism in calves. Am J Vet Res 70: 493-498, 2009.

Fecteau ME, Whitlock RH, Fyock TL, McAdams SC, Boston RC, Sweeney RW Antimicrobial activity of gallium nitrate against Mycobacterium avium subsp. paratuberculosis in neonatal calves J Vet Int Med 25: 1152-1155, 2011.

Sweeney RW, Collins MT, Koets AP, McGuirk SM, Roussel AJ ACVIM Consensus Statement: Paratuberculosis (Johne’s Disease) in cattle and other susceptible species Journal of Vet Int Med 26: 1239, 2012.

Sweeney RW., Uzonna J., Whitlock RH., Habecker PL., Chilton P., Scott P. Tissue predilection sites and effect of dose on Mycobacterium avium subs. paratuberculosis organism recovery in a short-term bovine experimental oral infection model Research in Veterinary Science 80: 253-9, 2006.

Uzonna JE., Chilton P., Whitlock RH., Habecker PL., Scott P., Sweeney RW. Efficacy of commercial and field-strain Mycobacterium paratuberculosis vaccinations with recombinant IL-12 in a bovine experimental infection model Vaccine 21: 3101-9, 2003.

Sweeney RW, Whitlock RH, McAdams S Comparison of three DNA preparation methods for real-time PCR confirmation of Mycobacterium avium subsp. paratuberculosis growth in an automated broth culture system Journal Veterinary Diagnostic Investigation 18: 587-590, 2006.

Sweeney RW., Jones DE., Habecker P., Scott P. Interferon-gamma and interleukin 4 gene expression in cows infected with Mycobacterium paratuberculosis American Journal of Veterinary Research 59: 842-7, 1998.

Sweeney RW., Whitlock RH., Rosenberger AE. Mycobacterium paratuberculosis cultured from milk and supramammary lymph nodes of infected asymptomatic cows Journal of Clinical Microbiology 30: 166-71, 1992.

Sweeney RW., Whitlock RH., Buckley CL., Spencer P., Rosenberger AE., Hutchinson LJ. Diagnosis of paratuberculosis in dairy cattle, using enzyme-linked immunosorbent assay for detection of antibodies against Mycobacterium paratuberculosis in milk American Journal of Veterinary Research 55: 905-9, 1994.

Johnson AL, McAdams-Gallagher SC, Sweeney RW Quantitative real-time PCR for detection of neurotoxin genes of Clostridium botulinum types A, B, and C in equine samples Veterinary Journal 199: 157, 2014.

Sielman ES., Sweeney RW., Whitlock RH., Reams RY. Hypokalemia syndrome in dairy cows: 10 cases (1992-1996) Journal of the American Veterinary Medical Association 210: 240-3, 1997.

A.B. (Chemistry) Dartmouth College, 1978

V.M.D. (Veterinary Medicine) University of Pennsylvania School of Veterinary Medicine, 1982

American College of Veterinary Internal Medicine Specialty of Large Animal Internal Medicine

University of Pennsylvania School of Veterinary Medicine- New Bolton Center (1982 to 1983)
Intern, Medicine and Surgery

University of Pennsylvania School of Veterinary Medicine- New Bolton Center (1983 to 1985)
Resident, Large Animal Internal Medicine