MARK A. OYAMA
Contact
New Bolton Center Kennett Square, PA
Emergencies & Appointments:
610-444-5800
Directions
Ryan Hospital Philadelphia, PA
Emergencies:
215-746-8911
Appointments:
215-746-8387
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MARK A. OYAMA, DVM, MSCE

Diplomate, American College of Veterinary Internal Medicine, Cardiology

Chair, Department of Clinical Sciences & Advanced Medicine, University of Pennsylvania School of Veterinary Medicine

Charlotte Newton Sheppard Endowed Chair of Medicine, University of Pennsylvania School of Veterinary Medicine

Professor, Department of Clinical Sciences & Advanced Medicine, University of Pennsylvania School of Veterinary Medicine

Associate Scholar, Center for Clinical Epidemiology and Biostatistics, Perelman School of Medicine, University of Pennsylvania

Clinical Specialties: Cardiology, Cardiac Examinations, Echocardiograms, ECG, Non-invasive & Invasive Surgeries,
Research Areas: Animal models of heart disease Heart Disease Myxomatous mitral valve disease Cardiac biomarkers Clinical trials Epidemiology Biostatistics Diuretic resistance
PubMed Link
Contact Information:
Department of Clinical Studies-Philadelphia
Ryan Veterinary Hospital of the University of Pennsylvania
School of Veterinary Medicine
University of Pennsylvania
3900 Spruce St.




Cardiac biomarkers (troponin, natriuretic peptides [BNP, ANP])
Diuretic resistance
Clinical trials
Serotonin signaling and myxomatous valve disease
Animal models of heart disease and heart failure
Epidemiology and biostatistics

Canine and feline models of heart disease
Molecular mechanisms of myxomatous mitral valve disease
Diuretic resistance
Epidemiology and biostatistics

Tinsley AT, Oyama MA, Reineke EL. Animal Trauma Triage Score, Modified Glasgow Coma Scale, age, and weight were associated with outcome in feline bite wounds (1,065 cases): a VetCOT registry study J Am Vet Med Assoc 261: 881-887, 2023.

Castillero E, Fitzpatrick E, Keeney SJ, D'Angelo AM, Pressly BB, Simpson MT, Kurade M, Erwin WC, Moreno V, Camillo C, Shukla HJ, Inamdar VV, Aghali A, Grau JB, Salvati E, Nissim I, Rauova L, Oyama MA, Stachelek SJ, Brown C, Krieger AM, Levy RJ, Ferrari G. Decreased serotonin transporter activity in the mitral valve contributes to progression of degenerative mitral regurgitation Sci Transl Med 15: eadc9606, 2023.

Pedro B, Mavropoulou A, Oyama MA, Linney C, Neves J, Dukes-McEwan J, Fontes-Sousa AP, Gelzer AR. Optimal rate control in dogs with atrial fibrillation-ORCA study-Multicenter prospective observational study: Prognostic impact and predictors of rate control J Vet Intern Med : , 2023.

Oyama MA, Adin D. Toward quantification of loop diuretic responsiveness for congestive heart failure J Vet Intern Med : , 2023.

Li Q, Larouche-Lebel É, Loughran KA, Huh TP, Suchodolski JS, Oyama MA. Metabolomics Analysis Reveals Deranged Energy Metabolism and Amino Acid Metabolic Reprogramming in Dogs With Myxomatous Mitral Valve Disease J Am Heart Assoc 10: e018923, 2021.

Li Q, Larouche-Lebel É, Loughran KA, Huh TP, Suchodolski JS, Oyama MA. Gut Dysbiosis and Its Associations with Gut Microbiota-Derived Metabolites in Dogs with Myxomatous Mitral Valve Disease mSystems 6: e00111-21, 2021.

Crooks AV, Gelzer AR, Oyama MA, Kraus MS. Quiet timer blanking in a dog with sick sinus syndrome and a permanent transvenous pacemaker J Vet Cardiol : , 2021.

Wilshaw J, Rosenthal SL, Wess G, Dickson D, Bevilacqua L, Dutton E, Deinert M, Abrantes R, Schneider I, Oyama MA, Gordon SG, Elliott J, Xia D, Boswood A. Accuracy of history, physical examination, cardiac biomarkers, and biochemical variables in identifying dogs with stage B2 degenerative mitral valve disease J Vet Intern Med : , 2021.

Oyama MA, Gelzer AR, Kraus MS. Letter regarding "Efficacy of adding ramipril (VAsotop) to the combination of furosemide (Lasix) and pimobendan (VEtmedin) in dogs with mitral valve degeneration: The VALVE trial" J Vet Intern Med : , 2021.

Larouche-Lebel É, Loughran KA, Huh T, Oyama MA. Effect of angiotensin receptor blockers and angiotensin converting enzyme 2 on plasma equilibrium angiotensin peptide concentrations in dogs with heart disease J Vet Intern Med : , 2021.

DVM (Doctor Veterinary Medicine) University of Illinois, 1994

MSCE (Masters of Science in Clinical Epidemiology) University of Pennslyvania, 2015

Diplomate, American College of Veterinary Internal Medicine, Cardiology

Animal Medical Center New York, NY (1994 to 1995)
Small Animal Internship

University of California Davis, CA (1995 to 1997)
Cardiology Residency