Welcome to PennGen Laboratories


PennGen Holiday Schedule

Please read the following carefully. The lab will be closed from December 24, 2021 until January 4, 2022 in accordance with University Winter holidays.

  • Urine and/or serum samples for Metabolic Screening, Fanconi Testing, Urine Nitroprusside Testing, and enzyme testing should be frozen and submitted after the holidays.
  • Samples for DNA testing (EDTA blood or cheek brushes/swabs) can be refrigerated and submitted after the holidays.
  • Due to the high volume of holiday packages for the US Postal Service combined with delays caused by the University’s Winter holiday schedule, we strongly encourage you to use a commercial carrier such as DHL, UPS or FedEx to avoid delays in the delivery of your samples.

Hereditary diseases of companion animals are an important problem for clinicians, breeders and owners. More than 900 inherited disorders have been identified in the dog and over 200 in the cat. At PennGen, we offer our customers the option of choosing from either DNA tests or Metabolic tests to better identify inherited and metabolic disorders.


Ready to Order Your Test?

When to choose a DNA test

Choose “DNA Tests” if you would like testing for a specific DNA variant in a specific breed.

  • These tests will require either cheek brushes or EDTA blood samples as a source of DNA for the test.
  • These tests are possible when a causative variant/mutation or a linked marker is known in a breed.
  • These tests are breed-specific. 
When to choose a metabolic test

If you suspect a metabolic defect, a storage disease including mucopolysaccharidosis or Fanconi  Syndrome in a patient, please choose “Metabolic Tests”. If you would like to assess the presence of cystine in the urine, please choose “Metabolic Tests”. These tests will require some combination of urine, serum, and/or blood smears for analysis of various metabolites, depending on the suspected disease.


Additional Services

Genetic Counseling 

  • If you would like to get genetic counseling, a confidential Medical Record will be made for you through PennGen at Penn Vet's Ryan Veterinary Hospital. Detailed written counseling reports are available for a fee of $150. Counseling regarding test results received from PennGen are free of charge.
  • Learn about genetics for breeders...
  • Sign up for genetic counseling...

Electron Microscopy 

  • If you are suspicious of a collagen defect or ciliary dyskinesia, please contact the lab for further information.
  • Why Use PennGen

    Hereditary diseases of companion animals are an important problem for clinicians, breeders and owners. More than 900 inherited disorders have been identified in the dog and over 200 in the cat.

    We at PennGen have been at the forefront of identifying and characterizing hereditary diseases in companion animals for more than 40 years, including research to uncover the molecular basis and developing DNA tests for canine and feline genetic diseases.

    We are a genetic testing facility operated through the Section of Clinical Genetics and Advanced Therapies (CGAT) as a group of laboratories offering testing for a variety of genetic diseases, metabolic screening for inborn errors of metabolism, and other diagnostic services.

Couldn't Find the Test You Need at PennGen?WSAVA

Use our WSAVA-supported database of worldwide laboratories to search for available canine and feline DNA-based genetic tests. The database search tool allows you to search by breed, disease, or laboratory.