Kyla Ortved and friend

Welcome to the Ortved Lab

The Ortved Laboratory at New Bolton Center is focused on understanding the pathophysiology of post-traumatic osteoarthritis (PTOA) and developing gene and cell-based therapies to help regenerate cartilage and prevent the development of PTOA following joint injury.

Due to the many similarities in joint biomechanics and propensity for PTOA, our lab uses the horse as a large animal model for human joint disease. Our goal is to develop translational regenerative therapies that would benefit both the equine and human patient.

Lab Mission

  • To improve cartilage repair using stem cell and gene therapy.
  • To limit the long-term effects of joint trauma through gene therapy immunomodulation of the joint.
  • To further elucidate the pathogenesis of post-traumatic osteoarthritis (PTOA). 

Interested in Working With Us?

We are always seeking highly motivated students and post-doctoral fellows with an interest in:

  • Orthopedic research
  • Joint disease
  • Stem cell therapy
  • Gene therapy
  • Regenerative medicine
  • Cartilage biology

Contact: Dr. Kyla Ortved at

Dr. Kyla Ortved, New Bolton Center 


New Bolton Center
382 W. Street Road
Kennett Square, PA