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Care for cats, dogs & other companion animals
[December 1, 2023; Philadelphia, PA] – Upon infection or immunization, all jawed vertebrate species generate proteins called antibodies that bind and neutralize pathogens. Strong and long-lasting antibody responses in warm-blooded species such as mammals are produced in secondary lymphoid microstructures (SLMs) among which germinal centers (GCs) are the centerpiece.
Two new studies led by Phillip Scott of the School of Veterinary Medicine and Elizabeth Grice of the Perelman School of Medicine demonstrate how bacteria found in leishmaniasis skin lesions and an associated immune response drive disease burden and treatment failure—and suggest new possibilities for treatment of the parasitic disease.
Researchers from the School of Veterinary Medicine and Perelman School of Medicine have shown that invariant natural killer T cells from a healthy donor can persist in MHC-mismatched canines, demonstrating a reliable platform to inform human clinical trials.
Daniel Beiting, PhD, associate director of the Institute for Infectious and Zoonotic Diseases, expanded his work this summer in the Galápagos, giving Stephanie Sila, V’25, an ideal opportunity to gain first-hand experience in identifying different mosquito species and human disease cases on the island.
The Environmental Innovations Initiative announces a third round of funded research communities to catalyze interdisciplinary research at Penn, investigating issues from regenerative agriculture to project-based learning for global climate justice.