Penn Vet | Cancer Clinical Trials
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New Bolton Center Kennett Square, PA
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610-444-5800
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Ryan Hospital Philadelphia, PA
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215-746-8911
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215-746-8387
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Clinical Support Services

Cancer Clinical Trials


Many diseases that occur in humans are also recognized in non-human species, and cancer is one of these diseases. At Penn Vet, the Veterinary Clinical Investigations Center (VCIC) provides the infrastructure to facilitate the translation of novel interventions from basic scientists to high quality investigations with naturally occurring diseases that parallel human conditions.

At the Penn Vet Cancer Center, we are uniquely positioned to study the impact of cancer research breakthroughs through this approach, not with laboratory animals, but with patients themselves. Conventionally, new medical advancements move from experiments with laboratory animals directly to human clinical trials. In clinical trials at Penn Vet, our patients present with spontaneous diseases in the same way humans do. By studying the impact of research models through clinical trials in client-owned animals whose day-to-day lives more closely resemble our own, scientists and doctors can better understand the outcome of therapeutics in patients.

In addition, our patients can more immediately benefit from breakthrough research conducted in strict protocols and controlled settings.


The Role of Pathology in Clinical Trials

Pathology plays an integral role in patient focused research by providing the necessary diagnostic and biocorrelative data.  The Comparative Pathology Core supports clinical trials at Penn Vet by providing expertise in tissue evaluation and state-of-the-art molecular and digital pathology techniques.


Clinical Trials

Evaluation of Flash Proton RT in Dogs with Bone Cancer of the Leg

A new type of radiation therapy for dogs with appendicular osteosarcoma

radiation therapy leg tumor leg cancer large dog cancer large breed cancer center cancer bone tumor bone cancer amputation

Clinical evaluation of propranolol and doxorubicin for the treatment of splenic hemangiosarcoma in the dog

In this trial, we will be evaluating Propranolol’s effect on survival time and quality of life when given in combination with the standard chemotherapy treatment.

inactive splenic HSA splenic hemangiosarcoma spleen propranolol PPL HSA hemangiosarcoma Dr. Pascal Salah Dr. Jennifer Mahoney doxorubicin chemotherapy cancer center cancer active cancer

Immunotherapy Clinical Trial for Dogs with Solid Tumors

New clinical trial using a sting agonist for various solid tumor types with a moderate to high risk of metastasis

inactive tumor surgery tumor surgery sting agonist squamous cell carcinoma soft tissue sarcoma osteosarcoma mass mammary carcinoma malignant melanoma immunotherapy growth dog cancer dog cancer active cancer

Intraoperative Detection and Resection of Tumors in Canines Using an Integrated Spectroscopy and Imaging System

A clinical trial to determine if near-infrared imaging can improve the surgeon’s ability to see cancer and cancer margins during surgery to remove primary lung tumors in dogs.

cancer active tumor surgery primary lung tumor Oncology metastasis mass margins lung tumor lung mass lung infrared Imaging Dr. David Holt diagnostic imaging comprehensive cancer care canine tumor canine lung tumor canine cancer cancer center cancer advanced imaging active

Comparison of the efficacy & impact on suppressor cells of CHOP vs. LOPP chemotherapy in canine T-cell lymphoma

CHOP vs. LOPP chemotherapy for T-cell Lymphoma

cancer active active lymphoma lymph node chemotherapy cancer

Soft Tissue Sarcoma & Mammary Carcinoma - Photoacoustic System for Identifying Tumor Edges (PSITE)

inactive tumor removal tumor soft tissue sarcoma mammary carcinoma cancer center cancer active cancer

Use of Near-infrared Imaging in Surgical Accuracy for Feline Soft-Tissue Sarcomas

Penn Vet is conducting a study to determine if near-infrared imaging can improve the surgeon’s ability to see cancer and cancer margins during surgery to remove feline soft tissue sarcomas.

inactive ryan surgery infrared imaging feline soft tissue sarcoma david holt cancer active