Penn Vet | News & Events
New Bolton Center Kennett Square, PA
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Ryan Hospital Philadelphia, PA

Cancer Center News

Department Highlights

Dr. Andres Blanco, Penn Vet M. Andrés Blanco, an assistant professor at the University of Pennsylvania School of Veterinary Medicine. and his colleagues have identified a new approach to triggering differentiation in AML—one with potential to treat a much wider array of AML patients. Their study, published in the journal Cancer Discovery, identifies an enzyme that regulates the process by which AML cells differentiate. In both cell lines and an animal model, the researchers found that inhibiting this enzyme, particularly in combination with other anti-cancer therapies, prompted AML cells to lose aspects of their identity associated with aggressive growth. The cells also began to exit the cell cycle, on the path toward maturing into a new cell type. Read the rest of the story...
Dr. Nicola Mason, Associate Professor of Medicine and PathobiologyFor dogs with osteosarcoma, a cancer of the bone, the standard treatment has been amputation combined with chemotherapy, and even that rarely staves off the cancer’s spread. Dr. Nicola Mason is embarking on a new way to treat the disease, using a novel immunotherapy-based vaccine to prevent metastasis to other organs. Read about Dr. Mason's clinical trial for canine cancer patients ...

Media Coverage

Penn Vet News Stories

Stroma targeting CAR T Cells suround a tumor

Removing the barrier surrounding solid tumors clears path for T cells

Penn researchers uncover a new way to target solid tumors. Using CAR T cells to remove cancer-associated fibroblasts surrounding pancreatic tumors allows T cells to infiltrate and attack the tumor cells.

Photo of Dr. Nicola Mason interviewed by Anderson Cooper

Penn Vet’s Dr. Nicola “Nicky” Mason Appears on 60 Minutes

The interview highlighted Dr. Mason’s role in leading clinical trials that evaluated a novel Listeria-based vaccine to treat pet dogs with osteosarcoma, a common canine bone cancer.


A FLASH of radiation may lead to new cancer care for people and pets alike

Led by the Perelman School of Medicine’s Keith Cengel and the School of Veterinary Medicine’s Brian Flesner, a new study is evaluating the safety and efficacy of treating oral cancer in dogs with a palliative radiation in just two clinic visits.


NIH-funded canine immunotherapy data center charts a path toward transformative therapies

With support recently for five more years, Nicola Mason of the School of Veterinary Medicine and Qi Long of the Perelman School of Medicine hope their work leads to new insights in cancer care for people as well as pets.