New Bolton Center Kennett Square, PA
Emergencies & Appointments:
Ryan Hospital Philadelphia, PA

Research Laboratories at Penn Vet

Penn Vet faculty are engaged in ongoing groundbreaking research. Here are examples of faculty laboratories and the projects being investigated, both at our Philadelphia campus and at New Bolton Center.

Ortved Orthopedic Regenerative Medicine Laboratory

Joint injuries are overwhelmingly common in both human and equine athletes. Chondrocytes, the sole cell type in cartilage, are responsible for producing and maintaining the extra-cellular matrix (ECM), which affords remarkable tensile and compressive strength to the joint surface. Once damaged, cartilage has little to no ability to heal itself. Therefore, post-traumatic osteoarthritis (PTOA) commonly develops following joint trauma, whether sustained during an acute injury or accumulated overtime.

Lab Mission

  • To improve cartilage repair using stem cell and gene therapy.
  • To limit the long-term effects of joint trauma through gene therapy immunomodulation of the joint.
  • To further elucidate the pathogenesis of post-traumatic osteoarthritis (PTOA).

Contact Information

Dr. Kyla Ortved, DVM, PhD, DACVS, DACVSMR 
Jacques Jenny Endowed Term Chair in Orthopedic Surgery,
University of Pennsylvania School of Veterinary Medicine