Penn Vet | All Clinical Trials
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Clinical Trials at Penn Vet


Here are all of the active clinical trials taking place at Penn Vet. Browse our list, which can be filtered by animal and trial type. 

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Treatment of abnormal heart rhythms in dogs

Our trial provides an option for dogs to undergo a surgical catheter procedure that targets the abnormal heart tissue making it unable to produce abnormal rhythms.

ryan cardiology trial ARVC CSAM Trial active cardiomyopathy arrhythmogenic right ventricular cardiomyopathy

New treatment for heart failure in dogs

Clinical trial of a new oral medication using plant-based encapsulation technology, which allows oral administration of drugs that would otherwise need to be given by injection.

active ryan cardiology trial ryan cardiology Myxomatous mitral valve disease mitral valve disease heart failure

New blood-based markers of disease in dogs

Penn Vet Companion Animal Cardiology in the process of discovering new blood-based markers of heart disease.

ryan cardiology trial ryan cardiology heart disease CSAM Trial blood-based markers active

Bladder Cancer - Evaluating an immunotherapy for dogs with Transitional Cell Carcinoma/Urothelial Carcinoma

Clinical trial evaluating an immunotherapy for dogs with bladder cancer

Mason Active cancer active active urothelial carcinoma transitional cell carcinoma TCC bladder cancer

Pilot Study of xenograft chimeric antigen receptor T cell therapy for drug resistant or refractory CD20+ B cell Lymphoma

T cell therapy for drug resistant B cell Lymphoma

Mason Active lymphoma dogs canine cancer active cancer B-cell lymphoma active

Elbow Osteoarthritis - A Randomized placebo controlled pilot study to evaluate A-18 in dogs with pain due to elbow osteoarthritis

A-18 for dogs with elbow osteoarthritis

active elbow pain Elbow osteoarthritis elbow arthritis arthritis

Evaluation of Nemo Binding Domain (NBD) peptide for dogs with soft tissue sarcoma

NBD Peptide for Soft Tissue Sarcoma

Mason Active tumor soft tissue sarcoma sarcoma mass cancer center Cancer Care cancer active

Comparison of the efficacy & impact on suppressor cells of CHOP vs. LOPP chemotherapy in canine T-cell lymphoma

CHOP vs. LOPP chemotherapy for T-cell Lymphoma

cancer active active lymphoma lymph node chemotherapy cancer

Clinical evaluation of propranolol and doxorubicin for the treatment of splenic hemangiosarcoma in the dog

In this trial, we will be evaluating Propranolol’s effect on survival time and quality of life when given in combination with the standard chemotherapy treatment.

cancer center splenic HSA splenic hemangiosarcoma spleen propranolol PPL HSA hemangiosarcoma chemotherapy cancer active cancer active

Evaluation of Flash Proton RT in Dogs with Bone Cancer of the Leg

A new type of radiation therapy for dogs with appendicular osteosarcoma

cancer center radiation therapy leg tumor leg cancer large dog cancer large breed cancer bone tumor bone cancer amputation active

Soft Tissue Sarcoma & Mammary Carcinoma - Photoacoustic System for Identifying Tumor Edges (PSITE)

cancer active tumor removal tumor soft tissue sarcoma mammary carcinoma cancer center cancer active

Clinical trial for dogs with arrhythmogenic right ventricular cardiomyopathy (ARVC)

The goal of this study is to explore options for monitoring and treating arrhythmias in dogs with ARVC.

active cardiomyopathy ARVC arrhythmia

Clinical & Safety Evaluation of SOCS1-KIR for the Treatment of Horses with Uveitis

This study evaluates the safety and effectiveness associated with the administration a new medication to positively impact comfort of the eye and prolong vision in horses diagnosed with unilateral or bilateral uveitis.

active vision in horses unilateral uveitis ophthalmology equine uveitis bilateral uveitis

Myasthenia Gravis - Determination of pathological autoantibodies in dogs with myasthenia gravis

Blood collection to assist in development of a biomarker that predicts the severity and prognosis of myathenia gravis

active weakness Neurology myasthenia gravis muscle weakness acetylcholine receptors

Evaluating the intestinal microbiome as a possible trigger for IMHA in dogs

The purpose of this study is to investigate whether the bacterial population of the GI tract may be a contributing factor to the onset of immune-mediated hemolytic anemia or thrombocytopenia in dogs.

active immune-mediated hemolytic anemia IMHA anemia

Study of two oral medications in treament of canine brain tumors

Evaluating safety and anti-cancer activity of oral PAC-1 used with hydroxyurea for canine meningioma

cancer active seizure meningioma brain tumor active

Study evaluating a novel prescription diet for dogs with heart murmurs.

A study evaluating whether a new prescription diet will slow the progression of mitral valve disease in dogs.

bad heart dog heart failure ECG mitral valve disease heart murmur heart disease heart echocardiogram cardiology cardiac active

Coagulation in Septic Peritonitis in Dogs

We are testing a heparin derivative that is anti-inflammatory without being anticoagulant.

abdomen septic belly septic abdomen septic peritonitis active

Use of Near-infrared Imaging in Surgical Accuracy for Feline Soft-Tissue Sarcomas

Penn Vet is conducting a study to determine if near-infrared imaging can improve the surgeon’s ability to see cancer and cancer margins during surgery to remove feline soft tissue sarcomas.

cancer active ryan surgery infrared imaging feline soft tissue sarcoma david holt active

Trial of ALVAC® IL-2 Treatment in Cats with Feline Fibrosarcoma

Clinical trial evaluating surgery in combination with immunotherapy for cats with fibrosarcoma

cancer active VAS vaccine tumor surgery sarcoma FSA cancer active