The IAP antagonist birinapant enhances chimeric antigen receptor T cell therapy for glioblastoma by overcoming antigen heterogeneity. Song EZ, Wang X, Philipson BI, Zhang Q, Thokala R, Zhang L, Assenmacher CA, Binder ZA, Ming GL, O'Rourke DM, Song H, Milone MC. Molecular Therapy: Oncolytics. 2022 Nov 15;27:288-304. doi: 10.1016/j.omto.2022.11.004.
Postmortem Study on the Effects of Routine Handling and Manipulation of Laboratory Mice. Assenmacher CA, Lanza M, Tarrant JC, Gardiner KL, Blankemeyer E, Radaelli E. Animals (Basel). 2022 Nov 22;12(23):3234. doi: 10.3390/ani12233234.
Chimeric antigen receptor T cells as adjuvant therapy for unresectable adenocarcinoma. Uslu U, Da T, Assenmacher CA, Scholler J, Young RM, Tchou J, June CH. Science Advances. 2023 Jan 13;9(2):eade2526. doi: 10.1126/sciadv.ade2526.
Tumor-Suppressive and Immune-Stimulating Roles of Cholesterol 25-hydroxylase in Pancreatic Cancer Cells. McBrearty N, Cho C, Chen J, Zahedi F, Peck AR, Radaelli E, Assenmacher CA, Pavlak C, Devine A, Yu P, Lu Z, Zhang H, Li J, Pitarresi JR, Astsaturov I, Cukierman E, Rustgi AK, Stanger BZ, Rui H, Fuchs SY. Molecular Cancer Research. 2023 Mar;21(3):228-239.
Inflammatory monocytes promote granuloma control of Yersinia infection. Sorobetea D, Matsuda R, Peterson ST, Grayczyk JP, Rao I, Krespan E, Lanza M, Assenmacher CA, Mack M, Beiting DP, Radaelli E, Brodsky IE. Nature Microbiology. 2023 Apr;8(4):666-678.
Spontaneous early-onset neurodegeneration in the brainstem and spinal cord of NSG, NOG, and NXG mice. Finesso G, Willis E, Tarrant JC, Lanza M, Sprengers J, Verrelle J, Banerjee E, Hermans E, Assenmacher CA, Radaelli E. Veterinary Pathology. 2023 May;60(3):374-383.
Advanced precision modeling reveals divergent responses of hepatocellular carcinoma to combinatorial immunotherapy. Liu J, Cheng L, El-Mekkoussi H, Assenmacher CA, Lee MYY, Jaffe DR, Garvin-Darby K, Morgan A, Manduchi E, Schug J, Kaestner KH. Cancer Communications. 2023 Jun;43(6):706-710. doi: 10.1002/cac2.12421.
Mitochondrial defects leading to arrested spermatogenesis and ferroptosis in the PARL deficient mouse model of Leigh Syndrome. Radaelli E, Assenmacher CA, Verrelle J, Banerjee E, Manero F, Khiati S, Girona A, Lopez-Lluch G, Navas P, Spinazzi M. Elife. 2023 Jul 28;12:e84710. doi: 10.7554/eLife.84710.
Desmoplastic stroma restricts T cell extravasation and mediates immune exclusion and immunosuppression in solid tumors. Xiao Z, Todd L, Huang L, Noguera-Ortega E, Lu Z, Huang L, Kopp M, Li Y, Pattada N, Zhong W, Guo W, Scholler J, Liousia M, Assenmacher CA, June CH, Albelda SM, Puré E. Nature Communications. 2023 Aug 22;14(1):5110. doi: 10.1038/s41467-023-40850-5.