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Thalamic neurons in an aged C57BL/6J mouse exhibit strong, deep purple, positive staining with phosphotungstic acid-haemotoxylin histochemical staining.
Thalamic neurons in an aged C57BL/6J mouse exhibit strong, deep purple, positive staining with phosphotungstic acid-haemotoxylin histochemical staining. Tarrant JC, Savickas P, Omodho L, Spinazzi M, Radaelli E. Spontaneous Incidental Brain Lesions in C57BL/6J Mice. Vet Pathol. 2019 Jul 4:300985819859878. doi: 10.1177/0300985819859878. [Epub ahead of print] PubMed PMID: 31272300.

CPC Publications


  1. Sorenmo KU, Durham AC, Radaelli E, Kristiansen V, Peña L, Goldschmidt MH, Stefanovski D. The estrogen effect; clinical and histopathological evidence of dichotomous influences in dogs with spontaneous mammary carcinomas. PLoS One. 2019 Oct 25;14(10):e0224504. doi: 10.1371/journal.pone.0224504. eCollection 2019. PubMed PMID: 31652293; PubMed Central PMCID: PMC6814212.

  2. Aghajanian H, Kimura T, Rurik JG, Hancock AS, Leibowitz MS, Li L, Scholler J, Monslow J, Lo A, Han W, Wang T, Bedi K, Morley MP, Linares Saldana RA, Bolar NA, McDaid K, Assenmacher CA, Smith CL, Wirth D, June CH, Margulies KB, Jain R, Puré E, Albelda SM, Epstein JA. Targeting cardiac fibrosis with engineered T cells. Nature. 2019 Sep;573(7774):430-433. doi: 10.1038/s41586-019-1546-z. Epub 2019 Sep 11. Erratum in: Nature. 2019 Nov 14;:. PubMed PMID: 31511695; PubMed Central PMCID: PMC6752964.

  3. Lawrence KM, McGovern PE, Mejaddam A, Rossidis AC, Baumgarten H, Kim AG, Grinspan JB, Licht DJ, Radaelli E, Rychik J, Peranteau WH, Davey MG, Flake AW, Gaynor JW. Prenatal hypoxemia alters microglial morphology in fetal sheep. J Thorac Cardiovasc Surg. 2019 Aug 28. pii: S0022-5223(19)31582-X. doi: 10.1016/j.jtcvs.2019.06.102. [Epub ahead of print] PubMed PMID: 31597618.

  4. Tarrant JC, Savickas P, Omodho L, Spinazzi M, Radaelli E. Spontaneous Incidental Brain Lesions in C57BL/6J Mice. Vet Pathol. 2019 Jul 4:300985819859878. doi: 10.1177/0300985819859878. [Epub ahead of print] PubMed PMID: 31272300.

  5. Larouche-Lebel É, Loughran KA, Oyama MA, Solter PF, Laughlin DS, Sánchez MD, Assenmacher CA, Fox PR, Fries RC. Plasma and tissue angiotensin-converting enzyme 2 activity and plasma equilibrium concentrations of angiotensin peptides in dogs with heart disease. J Vet Intern Med. 2019 Jul;33(4):1571-1584. doi: 10.1111/jvim.15548. Epub 2019 Jun 28. PubMed PMID: 31254308; PubMed Central PMCID: PMC6639469.

  6. Chattopadhyay M, Chowdhury AR, Feng T, Assenmacher CA, Radaelli E, Guengerich FP, Avadhani NG. Mitochondrially targeted cytochrome P450 2D6 is involved in monomethylamine-induced neuronal damage in mouse models. J Biol Chem. 2019 Jun 28;294(26):10336-10348. doi: 10.1074/jbc.RA119.008848. Epub 2019 May 20. PubMed PMID: 31113867; PubMed Central PMCID: PMC6664168.

  7. Joyeux L, Engels AC, Van Der Merwe J, Aertsen M, Patel PA, Deprez M, Khatoun A, Pranpanus S, da Cunha MGMCM, De Vleeschauwer S, Parra J, Apelt K, Laughlin MM, Van Calenbergh F, Radaelli E, Deprest J. Validation of the Fetal Lamb Model of Spina Bifida. Sci Rep. 2019 Jun 27;9(1):9327. doi: 10.1038/s41598-019-45819-3. PubMed PMID: 31249378; PubMed Central PMCID: PMC6597719.

  8. Wang S, El-Fahmawi A, Christian DA, Fang Q, Radaelli E, Chen L, Sullivan MC, Misic AM, Ellringer JA, Zhu XQ, Winter SE, Hunter CA, Beiting DP. Infection-Induced Intestinal Dysbiosis Is Mediated by Macrophage Activation and Nitrate Production. MBio. 2019 May 28;10(3). pii: e00935-19. doi:10.1128/mBio.00935-19. PubMed PMID: 31138751; PubMed Central PMCID: PMC6538788.

  9. Lawrence KM, McGovern PE, Mejaddam A, Rossidis AC, Baumgarten H, Kim A, Grinspan JB, Licht DJ, Didier RA, Vossough A, Radaelli E, Rychik J, Song L, Peranteau WH, Davey MG, Flake AW, Gaynor JW. Chronic intrauterine hypoxia alters neurodevelopment in fetal sheep. J Thorac Cardiovasc Surg. 2019 May;157(5):1982-1991. doi: 10.1016/j.jtcvs.2018.12.093. Epub 2019 Jan 11. PubMed PMID: 30745051; PubMed Central PMCID: PMC6690589.

  10. Bonvin E, Radaelli E, Bizet M, Luciani F, Calonne E, Putmans P, Nittner D, Singh NK, Santagostino SF, Petit V, Larue L, Marine JC, Fuks F. TET2-Dependent Hydroxymethylome Plasticity Reduces Melanoma Initiation and Progression. Cancer Res. 2019 Feb 1;79(3):482-494. doi: 10.1158/0008-5472.CAN-18-1214. Epub 2018 Dec 11. PubMed PMID: 30538121; PubMed Central PMCID: PMC6612266.

  11. Santagostino SF, Omodho LA, Francis A, De Vleeschauwer S, Meurrens K, Radaelli E. Pathology in Practice. Opportunistic Pseudomonas aeruginosa infection as cause of otitis media and labyrinthitis in immunocompetent mice. J Am Vet Med Assoc. 2019 Jan 15;254(2):221-224. doi: 10.2460/javma.254.2.221. PubMed PMID: 30605387.

  12. Spinazzi M, Radaelli E, Horré K, Arranz AM, Gounko NV, Agostinis P, Maia TM, Impens F, Morais VA, Lopez-Lluch G, Serneels L, Navas P, De Strooper B. PARL deficiency in mouse causes Complex III defects, coenzyme Q depletion, and Leigh-like syndrome. Proc Natl Acad Sci U S A. 2019 Jan 2;116(1):277-286. doi: 10.1073/pnas.1811938116. Epub 2018 Dec 21. PubMed PMID: 30578322; PubMed Central PMCID: PMC6320509.

  13. Radaelli E, Santagostino SF, Sellers RS, Brayton CF. Immune Relevant and Immune Deficient Mice: Options and Opportunities in Translational Research. ILAR J. 2018 Dec 31;59(3):211-246. doi: 10.1093/ilar/ily026. Review. PubMed PMID: 31197363.