Research Area

    Diagram showing R-loop processing and R-loop dynamics parallel apoptotic progression in IRD.

    Penn Vet Researchers Uncover a Shared Cellular Stress Signal that May Drive Vision Loss in Retinitis Pigmentosa

    Study finds buildup of unusual RNA-DNA loops in degenerating photoreceptors, pointing to a shared molecular stress pathway across distinct genetic forms of inherited blindness.

    A black lab being trained to sniff for specific items.

    Sniffing out cancer: Trained dogs can detect hemangiosarcoma by scent (link is external)

    Penn Vet’s Cynthia M. Otto and Clara Wilson and colleagues show that trained dogs can identify the odor of hemangiosarcoma, a devastating canine cancer, offering the hope of a better…

    Two people standing in a lab.

    Newly Identified Gene Deletion in Standard Poodles Sheds Light on Severe Vision Disorder

    Inherited retinal diseases form a broad and complex group of genetic conditions that cause progressive vision loss and blindness. Dogs, like humans, are susceptible to many such disorders. Because of…

    An image of a website that has images of a dogs retina.

    Vision Scientists at Penn Vet Launch DogAEye, a Novel AI-Based Tool To Improve Early Diagnosis of Retinal Degeneration in Dogs

    Veterinary ophthalmologists and vision scientists at the University of Pennsylvania’s School of Veterinary Medicine (Penn Vet) have announced the release of DogAEye, an innovative artificial intelligence (AI)–based clinical decision support…

    A person standing behind a podium.

    Penn Vet’s Nicola Mason, BVetMed, PhD, DACVIM, FRCVS, Receives Penn Center for Innovation’s Inventor of the Year Award

    The University of Pennsylvania (Penn) School of Veterinary Medicine (Penn Vet) congratulates Dr. Nicky Mason, the Paul A. James and Charles A. Gilmore Endowed Chair Professor and Professor of Medicine…

    three people posing with a dog in a veterinary office

    Dogs with cancer are helping save lives—both canine and human (link is external)

    The Comparative Immunotherapy Program led by Penn Vet’s Nicola Mason is redefining how therapies are developed and tested—uniting human and veterinary medicine to move promising immunotherapies forward.

    A person is examining a dog with an electronic device

    A New Penn Vet Clinic Brings Support and Hope for Dogs with Retinal Disease

    Zoey the cockapoo greeted life with tail-wagging joy. A mass of tawny curls, she loved everyone, and they loved her back.

    a diagram showing the process of using messenger RNA to make a protein

    Researchers Advance mRNA Delivery to the Retina Using Stabilized Lipid Carriers

    Efficient delivery of synthetic mRNA to the retina remains one of the key hurdles in developing mRNA-based treatments for vision loss.

    Two people standing in a lab.

    New genetic cause of blindness in dogs (link is external)

    In collaboration with a foundation that breeds service dogs for the visually impaired, researchers at the School of Veterinary Medicine at the University of Pennsylvania and the University of Padova…

    Dog walking on a treadmill.

    Ryan Hospital Launches Canine Hydrotherapy Services

    Addition of Underwater Treadmill Expands Treatment Options for Arthritis, Rehabilitation

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