New Bolton Center Kennett Square, PA
Emergencies & Appointments:
Ryan Hospital Philadelphia, PA

Mammalian Pathology Laboratory-New Bolton Center-PADLS

The Mammalian Pathology Laboratory Service at New Bolton Center is a constituent of the Pennsylvania Animal Diagnostic Lab System (PADLS) and provides complete autopsy and biopsy services to the patients of New Bolton and referrals from veterinarians throughout the state. Out-of-state cases are accepted for an additional fee (see PADLS fee schedule). Specialties include orthopedic pathology, infectious disease, veterinary forensics and translational animal models. Various histochemical and immunohistochemical techniques are employed to identify a variety of infectious agents and specific cell components in histology sections.

Large Animal Pathology

The combined resources and technical expertise of leading pathologists and scientists of New Bolton Center's Mammalian Pathology Laboratory Service, in conjunction with PADLS, provide state-of-the-art diagnostic technology supporting veterinarians’ efforts to advance animal and public health initiatives and support animal producers to ensure a safe, secure, and abundant food supply.

Contact Information

Business Hours:  8:00 a.m. to 5:00 p.m. Monday - Friday. For emergency consultation with a pathologist, please call (610) 444-5800.

Mammalian Pathology


New Bolton Center
382 West Street Road
Kennett Square, PA 19348

Fax:  610-925-6810

New Bolton Center's Mammalian Pathology Service is able to perform autopsies on a wide variety of species, including:

  • Horses
  • Cattle
  • Swine
  • Camelids
  • Sheep
  • Goats
  • Dogs and cats
  • Exotic (zoo) species

In addition to autopsies, the educated and experienced staff examine surgical biopsies and In addition to autopsies, the educated and experienced staff examine surgical biopsies and materials from postmortem exams performed by veterinarians in the field (“field posts”). The laboratory is also equipped to accept endometrial biopsies for evaluation. Tissues should be placed in 10% buffered formalin and submitted in containers and mailers specifically intended for formalin fixed specimens.

Immunohistochemistry (IHC) is the process of detecting antigens in cells by binding a labeled antibody to the antigen. This technique enables the identification of more than 30 infectious agents, including viruses, bacteria, and protozoa within the tissues of an animal.

  • Avian influenza
  • Bovine Viral Diarrhea – ear notches
  • Canine Distemper
  • Chronic Wasting Disease
  • Listeria monocytogenes
  • Porcine Respiratory & Reproductive Syndrome
  • Toxoplasma gondii
  • West Nile virus

The immunohistochemical technique also enables detection antigens expressed by neoplastic tissue (tumor antigens). For a detailed list of available services, fees, or the submission form, please click on the appropriate link below. To submit samples for testing, please fill out the submission form below and refer to the submission information section for information on shipping and sample preparation.


Available Testing

Submission Forms

Sample Preparation and Shipping Guidelines


  • Get directions
  • Business hours:  8:00 a.m. to 5:00 p.m. Monday - Friday. For emergency consultation with a pathologist, please call (610) 444-5800.

Research within the Mammalian Pathology Laboratory focuses on issues related to animal health and disease. Current topics of interest include:

  • Orthopedic disease (multiple species)
  • Equine and bovine laminitis
  • Equine intestinal microbiome and gastrointestinal disease

For more information regarding current research projects or to initiate a partnership for additional research, please contact the laboratory.

The expertise of the faculty and staff of the Mammalian Pathology Laboratory Service accommodates numerous opportunities for training in large animal pathology and anatomy for both veterinary students and pathology residents. Students and residents working in large animal pathology gain hands-on experience by assisting in necropsies, observing histopathology, and working one on one with a knowledgeable pathologist to learn more about specific disease processes.

In addition, the service accepts intramural and extramural externs to fulfill board certification requirements. Senior veterinary students from other schools are also welcome as externs. To learn more about the opportunities available for pathology residents and pre-veterinary and veterinary students, please contact the laboratory.

Julie Engiles
Susan Bender, VMD-PhD