New Bolton Center Kennett Square, PA
Emergencies & Appointments:
Ryan Hospital Philadelphia, PA

Large Animal Pathology Laboratory-PADLS

The Large Animal Pathology Service provides complete necropsy and biopsy services to the patients of New Bolton and referrals from veterinarians throughout the state.

Immunohistochemistry adds a special dimension to Widener Hospital’s diagnostic service and to the work of Penn researchers. This special staining technique uses color-labeled antibodies to identify infectious agents and special cell compLarge Animal Pathologyonents in histology sections. 

As part of PADLS, the Large Animal Pathology Service supports PADLS’ program objectives and mission.

The combined resources and technical expertise of leading scientists at PADLS laboratories provide state-of-the-art diagnostic technology supporting veterinarians’ efforts to advance animal and public health initiatives and support producers in assuring a safe, secure, and abundant food supply.

Contact Information

Business Hours:  8:00 a.m. to 5:00 p.m. Monday - Friday. For emergency consultation with a pathologist, please call (610) 444-5800.

Mammalian Pathology


New Bolton Center
382 West Street Road
Kennett Square, PA 19348

Fax:  610-925-6810


Relevant Links


The large animal pathology service is able to perform necropsies on a wide variety of mammals including:

  • Horses
  • Cattle
  • Swine
  • Camelids
  • Sheep
  • Goats
  • Exotic species

In addition to necropsies, the educated and experienced staff examine surgical biopsies and field necropsy material. The laboratory is also equipped to accept endometrial biopsies for evaluation. Tissues should be placed in 10% buffered formalin and submitted in containers and mailers specifically intended for formalin fixed specimens.

Immunohistochemistry (IHC) is the process of detecting antigens in cells by binding a labeled antibody to the antigen. This technique enables the identification of viruses, bacteria, and protozoa within the tissues of an animal. The large animal pathology service can perform IHC on over 30 different infectious agents including:

  • Avian influenza
  • Bovine Viral Diarrhea – ear notches
  • Canine Distemper
  • Listeria monocytogenes
  • Porcine Respiratory & Reproductive Syndrome
  • Toxoplasma gondii
  • West Nile virus

For a detailed list of available services, fees, or the submission form, please click on the appropriate link below. To submit samples for testing, please fill out the form below and refer to the submission information section for information on shipping and sample preparation.


Available Testing

Submission Forms

Sample Preparation and Shipping Guidelines


  • Get directions
  • Business hours:  8:00 a.m. to 5:00 p.m. Monday - Friday. For emergency consultation with a pathologist, please call (610) 444-5800.

Research within the Pathology Laboratory focuses on issues related to animal health and disease. Current topics of interest include:

  • Orthopedic disease (multiple species)
  • Equine and bovine laminitis
  • Equine intestinal microbiome and gastrointestinal disease

For more information regarding current research projects or to initiate a partnership for additional research, please contact the laboratory.

The expertise of the faculty and staff of the Large Animal Pathology Service accommodates numerous opportunities for training in large animal pathology and anatomy for both veterinary students and pathology residents. Students and residents working in large animal pathology gain hands-on experience by assisting in necropsies, observing histopathology, and working one on one with a knowledgeable pathologist to learn more about specific disease processes.

In addition, the service accepts intramural and extramural externs to fulfill board certification requirements. Senior veterinary students from other schools are also welcome as externs. To learn more about the opportunities available for pathology residents and pre-veterinary and veterinary students, please contact the laboratory.

Julie Engiles
Susan Bender, VMD-PhD